Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Luca Baumer"'
Autor:
Mario Varasi, Carla Caccia, Enzo Brambilla, Luca Baumer, Robert A. McArthur, Sergio Mantegani, M. G. Fornaretto
Publikováno v:
European Journal of Medicinal Chemistry. 33:279-292
The synthesis and the structure-affinity relationship (S.A.F.I.R.) study for the 5-HT 1A receptor sites of a novel series of 5(10→9) abeo -ergoline derivatives are presented. Most derivatives showed moderate to high affinity and selectivity for 5-H
Publikováno v:
Biopolymers. 41:731-749
The 64 amino acid hirudin-like peptide HM2 (Hirudinaria manillensis) is one of the agents known to specifically block the blood-clotting enzyme thrombin, and therefore is used as a potential pharmacological tool for the treatment of arterial and veno
Publikováno v:
Tetrahedron. 49:3367-3386
The location and evaluation of interfering functionalities are aspects of great importance in the synthesis planning, because the success of a synthesis often depends on the correct management of functionalities involved both in the formation of the
Publikováno v:
ChemInform. 22
A first section involved in reactivity prediction has been introduced in a program for computer-aided organic synthesis planning. The concepts of native polarity, induced polarity, and effective polarity have been used to determine the best electroni
Publikováno v:
ChemInform. 22
The general basis of the LILITH program is outlined. The size of the possible solution space is reduced by enhancing convergence, simplification and ordering. Complexity distance, relevant bond sets and ordering for bond-forming sequences are describ
Autor:
Sergio Mantegani, Mario Varasi, Robert A. McArthur, Luca Baumer, Enzo Brambilla, M. G. Fornaretto, Carla Caccia
Publikováno v:
ChemInform. 29
The synthesis and the structure-affinity relationship (S.A.F.I.R.) study for the 5-HT 1A receptor sites of a novel series of 5(10→9) abeo -ergoline derivatives are presented. Most derivatives showed moderate to high affinity and selectivity for 5-H
Autor:
Luca Baumer, Guido Sello
Publikováno v:
Journal of Chemical Information and Computer Sciences. 32:125-130
Autor:
Nicoletta Crespi Perellino, Marzia Ballabio, Franco Francesco Vincieri, Luca Baumer, Anacleto Minghetti, E. Arlandini, Daniela Borghi
Publikováno v:
Journal of Natural Products. 54:1503-1508
Publikováno v:
Journal of the American Chemical Society. 113:2494-2500
A first section involved in reactivity prediction has been introduced in a program for computer-aided organic synthesis planning. The concepts of native polarity, induced polarity, and effective polarity have been used to determine the best electroni
Publikováno v:
Computers & Chemistry. 15:293-299
An original algorithm for ring perception in organic chemical structures is presented. It divides rings into two classes to be separately investigated, simplifies the molecular graph and, without finding all possible cycles, efficiently identifies on