Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Luca Bagnasco"'
1
Selection and Characterization of Single Stranded DNA Aptamers for the Hormone Abscisic Acid
Autor: Tiziana Vigliarolo, Annalisa Salis, Víctor M. González, Enrico Millo, Cristina D'Arrigo, Elena Zocchi, Lucrezia Guida, Luca Bagnasco, Elena M. Martin, Marta Bellotti, Antonio De Flora, Laura Sturla, Alessia Grozio
Publikováno v: Nucleic acid therapeutics
23 (2013): 322–331. doi:10.1089/nat.2013.0418
info:cnr-pdr/source/autori:Grozio A.; Gonzalez VM.; Millo E.; Sturla L.; Vigliarolo T.; Bagnasco L.; Guida L.; D'Arrigo C.; De Flora A.; Salis A.; Martin EM.; Bellotti M.; Zocchi E./titolo:Selection and characterization of single stranded DNA aptamers for the hormone abscisic acid/doi:10.1089%2Fnat.2013.0418/rivista:Nucleic acid therapeutics (Print)/anno:2013/pagina_da:322/pagina_a:331/intervallo_pagine:322–331/volume:23
The hormone abscisic acid (ABA) is a small molecule involved in pivotal physiological functions in higher plants. Recently, ABA has been also identified as an endogenous hormone in mammals, regulating different cell functions including inflammatory p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b059fc51e5b4b14998e843a6a8c3403e
https://doi.org/10.1089/nat.2013.0418
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2
Role of Angiogenesis Inhibitors in Colorectal Cancer: Sensitive and Insensitive Tumors
Autor: Gabriele Zoppoli, Alberto Ballestrero, Franco Patrone, Daniela Piras, Luca Bagnasco, Inga Bauer, Silvio Parodi
Publikováno v: Current Cancer Drug Targets. 12:303-315
Angiogenesis is a key factor in the carcinogenesis process. In oncological practice, angiogenesis inhibition, mainly through the blockade of the VEGF family and its receptors, has been robustly demonstrated to produce clinical benefits and, in specif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73567e3d8512ec171884ca62b16ede0e
https://doi.org/10.2174/156800912800190929
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3
Functional characterization of a synthetic abscisic acid analog with anti-inflammatory activity on human granulocytes and monocytes
Autor: Chiara Fresia, Andrea Galatini, Alessia Grozio, Annalisa Salis, Laura Sturla, Elena Zocchi, Luca Bagnasco, Gianluca Damonte, Marta Bellotti, Antonio De Flora, Mirko Magnone, Tiziana Vigliarolo, Enrico Millo, Santina Bruzzone, Lucrezia Guida
Publikováno v: Biochemical and Biophysical Research Communications. 415:696-701
The phytohormone abscisic acid (ABA), in addition to regulating several important physiological functions in plants, is also produced and released by human granulocytes and monocytes where it stimulates cell activities involved in the innate immune r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc476d5c7050d57b8a8af5e27bfddc1
https://doi.org/10.1016/j.bbrc.2011.10.143
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4
Ras-Induced Resistance to Lapatinib is Overcome by MEK Inhibition
Autor: Gabriele Zoppoli, Silvio Parodi, Filippo Ansaldi, Michele Cea, Eva Moran, Debora Soncini, Alessio Nencioni, Alberto Ballestrero, Gabriella Cirmena, Valentina Grillo, Franco Patrone, Luca Bagnasco, Anna Garuti, Giancarlo Icardi, Ilaria Rocco
Publikováno v: Current Cancer Drug Targets. 10:168-175
Lapatinib, a dual HER2 and EGFR tyrosine kinase inhibitor is highly active in HER2+ breast cancer. However, its efficacy is limited by either primary or acquired resistance. Although mutations in ras genes are rarely found in breast cancer, H-ras ove
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c015fd3ab32e67181b27d8d038d17d20
https://doi.org/10.2174/156800910791054211
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5
Proteomic analysis of the nuclear matrix in the early stages of rat liver carcinogenesis: Identification of differentially expressed and MAR-binding proteins
Autor: Cecilia Balbi, Paola Barboro, Erica Repaci, Cristina D'Arrigo, Luca Bagnasco, Paola Orecchia, Barbara Carnemolla, Eligio Patrone
Publikováno v: Experimental cell research 315 (2009): 226–239. doi:10.1016/j.yexcr.2008.10.017
info:cnr-pdr/source/autori:Barboro P.; D'Arrigo C.; Repaci E.; Bagnasco L.; Orecchia P.; Carnemolla B.; Patrone E.; Balbi C./titolo:Proteomic analysis of the nuclear matrix in the early stages of rat liver carcinogenesis: identification of differentially expressed and MAR-binding proteins/doi:10.1016%2Fj.yexcr.2008.10.017/rivista:Experimental cell research/anno:2009/pagina_da:226/pagina_a:239/intervallo_pagine:226–239/volume:315
Tumor progression is characterized by definite changes in the protein composition of the nuclear matrix (NM). The interactions of chromatin with the NM Occur via specific DNA sequences called MARS (matrix attachment regions). In the present study, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5785bd9b51a4f46b5af2d8534da359d9
https://doi.org/10.1016/j.yexcr.2008.10.017
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6
Internalization via Antennapedia protein transduction domain of an scFv antibody toward c‐Myc protein
Autor: Laura Chiossone, C. Avignolo, Valeria Tomati, Inga Bauer, Annalisa Salis, Paola Orecchia, Luca Bagnasco, Silvio Parodi, Barbara Carnemolla, Melchiori A, M. C. Mingari, L. Zardi, B. Biasotti, Dario Neri
Publikováno v: The FASEB Journal. 22:1237-1245
We constructed a single-chain variable fragment miniantibody (G11-scFv) directed toward the transactivation domain of c-Myc, which is fused with the internalization domain Int of Antennapedia at its carboxyl terminus (a cargo-carrier construct). In E
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bea5607d15c57b099884479ead07a34
https://doi.org/10.1096/fj.07-8865com
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8
A transgenic mouse model for the detection of cellular stress induced by toxic inorganic compounds
Autor: Cinzia Parolini, Libero Clerici, Romeo Roncucci, Luigi Zecca, Luca Bagnasco, Enrica Mira Catò, Giulia Chiesa, Peter Bromley, Paolo Vezzoni, Maria Grazia Sacco
Publikováno v: Nature Biotechnology. 15:1392-1397
Transgenic mice for genotoxicity testing have been developed, although no such models have been produced for the evaluation of toxic, nongenotoxic chemical compounds. We have developed a transgenic mouse model for the analysis of toxic inorganic comp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a58504dc8e81cb534173a0ae3c8a3a
https://doi.org/10.1038/nbt1297-1392
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9
Dynamic Simulations of Pathways Downstream of TGFβ, Wnt and EGF-Family Growth Factors, in Colorectal Cancer, including Mutations and Treatments with Onco-Protein Inhibitors
Autor: Franco Patrone, Annalisa Barla, Alberto Ballestrero, Silvio Parodi, Luca Bagnasco, Daniela Piras, Nicoletta Castagnino, Alessandro Verri, Gabriele Zoppoli, Lorenzo Tortolina, Cristina De Ambrosi
Publikováno v: New Challenges for Cancer Systems Biomedicine ISBN: 9788847025707
With reference to colorectal cancer, we have reconstructed a Molecular Interaction Map downstream of TGFβ, Wnt and EGF-family. Based on an extensive and systematic direct/indirect data extrapolation from several dozens of published experimental pape
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::650a98a1c030860fb101e048ade83cdb
https://doi.org/10.1007/978-88-470-2571-4_7
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10
Binding of abscisic acid to human LANCL2
Autor: Luca Bagnasco, Laura Sturla, Enrico Millo, Santina Bruzzone, Antonio De Flora, Elena Mannino, Chiara Fresia, Alessia Grozio, Elena Zocchi, Tiziana Vigliarolo, Lucrezia Guida
Publikováno v: Biochemical and biophysical research communications. 415(2)
The phytohormone abscisic acid (ABA) is the central regulator of abiotic stress in plants and plays important roles during plant growth and development. In animal cells, ABA was shown to be an endogenous hormone, acting as a stress signal and stimula
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc82afb0933f17cd3524ab76e5aacd78
https://pubmed.ncbi.nlm.nih.gov/22037458
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