Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Luca Azzolin"'
Autor:
Giorgio Luongo, MSc, Luca Azzolin, MSc, Steffen Schuler, MSc, Massimo W. Rivolta, PhD, Tiago P. Almeida, PhD, Juan P. Martínez, PhD, Diogo C. Soriano, PhD, Armin Luik, MD, Björn Müller-Edenborn, MD, Amir Jadidi, MD, Olaf Dössel, PhD, Roberto Sassi, PhD, Pablo Laguna, PhD, Axel Loewe, PhD
Publikováno v:
Cardiovascular Digital Health Journal, Vol 2, Iss 2, Pp 126-136 (2021)
Background: Atrial fibrillation (AF) is the most common supraventricular arrhythmia, characterized by disorganized atrial electrical activity, maintained by localized arrhythmogenic atrial drivers. Pulmonary vein isolation (PVI) allows to exclude PV-
Externí odkaz:
https://doaj.org/article/946de344e92d48cfb0257024a32dae0f
Autor:
Giulia Della Chiara, Federica Gervasoni, Michaela Fakiola, Chiara Godano, Claudia D’Oria, Luca Azzolin, Raoul Jean Pierre Bonnal, Giulia Moreni, Lorenzo Drufuca, Grazisa Rossetti, Valeria Ranzani, Ramona Bason, Marco De Simone, Francesco Panariello, Ivan Ferrari, Tanya Fabbris, Francesca Zanconato, Mattia Forcato, Oriana Romano, Jimmy Caroli, Paola Gruarin, Maria Lucia Sarnicola, Michelangelo Cordenonsi, Alberto Bardelli, Nicola Zucchini, Andrea Pisani Ceretti, Nicolò Maria Mariani, Andrea Cassingena, Andrea Sartore-Bianchi, Giuseppe Testa, Luca Gianotti, Enrico Opocher, Federica Pisati, Claudio Tripodo, Giuseppe Macino, Salvatore Siena, Silvio Bicciato, Stefano Piccolo, Massimiliano Pagani
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The role of epigenetic deregulation in colorectal cancer (CRC) is not fully understood yet. Here the authors use patient-derived organoids, epigenomics and single-cell RNA-seq to reveal that YAP/TAZ are key regulators that bind to active enhancers in
Externí odkaz:
https://doaj.org/article/d24dcbd0a4754b4e8fdf6d5dd0925565
Publikováno v:
Mathematics in Engineering, Vol 2, Iss 4, Pp 614-638 (2020)
This work concerns the mathematical and numerical modeling of the heart. The aim is to enhance the understanding of the cardiac function in both physiological and pathological conditions. Along this road, a challenge arises from the multi-scale and m
Externí odkaz:
https://doaj.org/article/aebb365c2bb641ed8b6829d499db37e3
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
In both clinical and computational studies, different pacing protocols are used to induce arrhythmia and non-inducibility is often considered as the endpoint of treatment. The need for a standardized methodology is urgent since the choice of the prot
Externí odkaz:
https://doaj.org/article/76c9cefef07144f691ee88e89138f064
Autor:
Antonio Totaro, Martina Castellan, Giusy Battilana, Francesca Zanconato, Luca Azzolin, Stefano Giulitti, Michelangelo Cordenonsi, Stefano Piccolo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Notch signalling is a fundamental negative regulator of epidermal stemness. Here, the authors show that cell mechanics through YAP/TAZ activity prevent primary human keratinocytes from differentiating by inhibiting cell-autonomous Notch signals.
Externí odkaz:
https://doaj.org/article/594670e97aba451c8912bf09316bfecd
Autor:
Luca Azzolin, Nicola Antolini, Andrea Calderan, Paolo Ruzza, Marco Sciacovelli, Oriano Marin, Stefano Mammi, Paolo Bernardi, Andrea Rasola
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16280 (2011)
Antamanide is a cyclic decapeptide derived from the fungus Amanita phalloides. Here we show that antamanide inhibits the mitochondrial permeability transition pore, a central effector of cell death induction, by targeting the pore regulator cyclophil
Externí odkaz:
https://doaj.org/article/509d01af1c4041609345b444af119fba
Autor:
Vincenzo Bronte, Peter J. Murray, Silvio Bicciato, Emilio Bria, Luisa Carbognin, Aldo Scarpa, Rita Lawlor, Stefano Piccolo, Luca Azzolin, Nir Hacohen, David Lieb, Siranush Sarkizova, Thomas Eisenhaure, Giulia Borile, Federico Boschi, Massimo Rugge, Matteo Fassan, Manuela Iezzi, Alessia Lamolinara, Anna Simonelli, Stefania Canè, Stefano Ugel, Francesco De Sanctis, Vincenzo Ingangi, Francesca Hofer, Rosalinda Trovato, Ilaria Marigo
Tumor-associated macrophages (TAM) are regulators of extracellular matrix (ECM) remodeling and metastatic progression, the main cause of cancer-associated death. We found that disabled homolog 2 mitogen-responsive phosphoprotein (DAB2) is highly expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c952050333b46b1b7c684b390757b60e
https://doi.org/10.1158/2159-8290.c.6547787.v1
https://doi.org/10.1158/2159-8290.c.6547787.v1
Autor:
Vincenzo Bronte, Peter J. Murray, Silvio Bicciato, Emilio Bria, Luisa Carbognin, Aldo Scarpa, Rita Lawlor, Stefano Piccolo, Luca Azzolin, Nir Hacohen, David Lieb, Siranush Sarkizova, Thomas Eisenhaure, Giulia Borile, Federico Boschi, Massimo Rugge, Matteo Fassan, Manuela Iezzi, Alessia Lamolinara, Anna Simonelli, Stefania Canè, Stefano Ugel, Francesco De Sanctis, Vincenzo Ingangi, Francesca Hofer, Rosalinda Trovato, Ilaria Marigo
Supplementary Figures, Tables, Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a214a6f2439b7d663c90e03d1246aeb
https://doi.org/10.1158/2159-8290.22535201
https://doi.org/10.1158/2159-8290.22535201
Autor:
Vincenzo Bronte, Peter J. Murray, Silvio Bicciato, Emilio Bria, Luisa Carbognin, Aldo Scarpa, Rita Lawlor, Stefano Piccolo, Luca Azzolin, Nir Hacohen, David Lieb, Siranush Sarkizova, Thomas Eisenhaure, Giulia Borile, Federico Boschi, Massimo Rugge, Matteo Fassan, Manuela Iezzi, Alessia Lamolinara, Anna Simonelli, Stefania Canè, Stefano Ugel, Francesco De Sanctis, Vincenzo Ingangi, Francesca Hofer, Rosalinda Trovato, Ilaria Marigo
Marker genes for each cell type identified in tumor-infiltrating myeloid cells.Related to Fig.1A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436a07667db2edfb83bc552bd33586f8
https://doi.org/10.1158/2159-8290.22535213
https://doi.org/10.1158/2159-8290.22535213
Publikováno v:
Current Directions in Biomedical Engineering, Vol 7, Iss 2, Pp 136-139 (2021)
Current Directions in Biomedical Engineering, 7 (2), 136-139
Current Directions in Biomedical Engineering, 7 (2), 136-139
Modeling the 'digital twin' of a patient's heart has gained traction in the last years and helps to understand the pathogenic mechanisms of cardiovascular disease to pave the way for personalized therapies. Although a 3D patient-specific model (PSM)