Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Luca Agnetta"'
Autor:
Jose Manuel Sánchez-Sánchez, Fabio Riefolo, Almudena Barbero-Castillo, Rosalba Sortino, Luca Agnetta, Marta Forcella, Miquel Bosch, Michael Decker, Pau Gorostiza, Maria Sanchez-Vives
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 392-393 (2023)
Externí odkaz:
https://doaj.org/article/baad84490dab41f08a0b0077ea33c29d
Autor:
Simon Schramm, Matthias Irmen, Christian Tränkle, Michael Decker, Timo Littmann, Hubert Gerwe, Gerhard Wolber, Luca Agnetta, Marcel Bermudez, Janine Holze
Publikováno v:
ChemMedChem. 14:1349-1358
Recently, investigations of the complex mechanisms of allostery have led to a deeper understanding of G protein-coupled receptor (GPCR) activation and signaling processes. In this context, muscarinic acetylcholine receptors (mAChRs) are highly releva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a2e20d3265aa2902aa274db5a4008b
https://doi.org/10.1002/cmdc.201900283
https://doi.org/10.1002/cmdc.201900283
Autor:
Timo Littmann, Enrique Claro, Marcel Bermudez, Ulrike Holzgrabe, Gerhard Wolber, Luca Agnetta, Regina Messerer, Michael Decker, Carlo Matera, Fabio Riefolo
Publikováno v:
Journal of Medicinal Chemistry. 62:3009-3020
Red-shifted azobenzene scaffolds have emerged as useful molecular photoswitches to expand potential applications of photopharmacological tool compounds. As one of them, tetra- ortho-fluoro azobenzene is well compatible for the design of visible-light
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d61e30c3a6e2073b68538c1b0b983f
https://doi.org/10.1021/acs.jmedchem.8b01822
https://doi.org/10.1021/acs.jmedchem.8b01822
Autor:
Regina Messerer, Luca Agnetta, Carsten Hoffmann, Ulrike Holzgrabe, Maria Consuelo Alonso Canizal, Michael Decker, Michael Kauk
Publikováno v:
Angewandte Chemie. 129:7388-7393
Uber die Art und den zeitlichen Verlauf der Aktivierung von G-Protein-gekoppelten Rezeptoren (GPCRs), insbesondere der muskarinischen Acetylcholinrezeptoren (mACh- oder M-Rezeptoren), ist trotz der enormen therapeutischen Relevanz von M-Rezeptoren un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19f194052521672abd354863ac22c57e
https://doi.org/10.1002/ange.201701524
https://doi.org/10.1002/ange.201701524
Autor:
Carlo Matera, Alexandre M. J. Gomila, Ulrike Holzgrabe, Enrique Claro, Eduard Guasch, Fabio Riefolo, Pau Gorostiza, Michael Decker, Aida Garrido-Charles, Montserrat Batlle, Roser Masgrau, Luca Agnetta
Remote control of physiological functions with light offers the promise of unveiling their complex spatiotemporal dynamics in vivo, and enabling highly focalized therapeutic interventions with reduced systemic toxicity. Optogenetic methods have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5187e88e61803e404ffc09684150966
https://doi.org/10.26434/chemrxiv.7472174.v1
https://doi.org/10.26434/chemrxiv.7472174.v1
Autor:
Michael Decker, Michael Kauk, Luca Agnetta, Maria Consuelo Alonso Canizal, Ulrike Holzgrabe, Carsten Hoffmann, Regina Messerer
Publikováno v:
Angewandte Chemie (International ed. in English). 56(25)
The investigation of the mode and time course of the activation of G-protein-coupled receptors (GPCRs), in particular muscarinic acetylcholine (mACh or M) receptors, is still in its infancy despite the tremendous therapeutic relevance of M receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222c47c73ee2f19333b0df1150eb2930
https://pubmed.ncbi.nlm.nih.gov/28510314
https://pubmed.ncbi.nlm.nih.gov/28510314
Autor:
Luca Agnetta, Maria Laura Bolognesi, Salvatore Bongarzone, Giovanni Bottegoni, María do Carmo Carreiras, Andrea Cavalli, Kelly Chibale, Michael Decker, Dominik Dolles, John F. Gilmer, Liu He, Guozheng Huang, Lhassane Ismaili, José Marco-Contelles, Diego Muñoz-Torrero, Peter Mbugua Njogu, John Okombo, Federica Prati, Alejandro Romero, John M. Saathoff, Elisa Uliassi, Shijun Zhang, Qingjie Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5677f55d1c838fea5d9b976a5938be20
https://doi.org/10.1016/b978-0-08-101011-2.00016-7
https://doi.org/10.1016/b978-0-08-101011-2.00016-7
Autor:
Michael Decker, Luca Agnetta
Photoresponsive hybrid compounds allow adjusting drug activity and selectivity in a reversible fashion using light as a specific regulator and therefore providing high spatiotemporal resolution. This field, also called photopharmacology, has reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::708c4b2cbb5ead15e41d93000484d268
https://doi.org/10.1016/b978-0-08-101011-2.00011-8
https://doi.org/10.1016/b978-0-08-101011-2.00011-8
Autor:
Carlo Matera, Luca Agnetta, Fabio Riefolo, Pau Gorostiza, Enrique Claro, Michael Decker, Aida Garrido-Charles, Eduard Guasch, Ulrike Holzgrabe, R. Sortino, Montserrat Batlle, Alexandre M. J. Gomila, Roser Masgrau
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Light-triggered reversible modulation of physiological functions offers the promise of enabling on-demand spatiotemporally controlled therapeutic interventions. Optogenetics has been successfully implemented in the heart, but significant barriers to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c2712d0923af3b5678debc1e77a322
http://hdl.handle.net/2445/147236
http://hdl.handle.net/2445/147236