Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Luca A Finelli"'
Publikováno v:
PLoS Computational Biology, Vol 4, Iss 4, p e1000062 (2008)
Neural circuits exploit numerous strategies for encoding information. Although the functional significance of individual coding mechanisms has been investigated, ways in which multiple mechanisms interact and integrate are not well understood. The lo
Externí odkaz:
https://doaj.org/article/69e2572dc6b24dfa84b04be50b0e1e8e
Autor:
Vas Narasimhan, Luca A. Finelli
Publikováno v:
Clinical Pharmacology and Therapeutics
We are experiencing seminal times in computing that seem to define a fourth industrial revolution. This may fundamentally change the way we live, work, and relate to one another. Embracing data and digital information is a top priority for most indus
Publikováno v:
IEEE BigData
COVID-19 clinical trial design is a critical task in developing therapeutics for the prevention and treatment of COVID-19. In this study, we apply a deep learning approach to extract eligibility criteria variables from COVID-19 trials to enable quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a549578c445252d27530749c8a7d05
http://arxiv.org/abs/2012.10063
http://arxiv.org/abs/2012.10063
Autor:
Luca A. Finelli, Donald R. Stanski, Thomas Dimke, Steven E. Kern, Gabriel Helmlinger, Andreas Kuttler
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics
We introduce how biophysical modeling in pharmaceutical research and development, combining physiological observations at the tissue, organ and system level with selected drug physiochemical properties, may contribute to a greater and non-intuitive u
Publikováno v:
European Journal of Neuroscience. 13:2282-2290
The sleep EEG of healthy young men was recorded during baseline and recovery sleep after 40 h of waking. To analyse the EEG topography, power spectra were computed from 27 derivations. Mean power maps of the nonREM sleep EEG were calculated for 1-Hz
Publikováno v:
Neuroscience. 101:523-529
To investigate the relationship between markers of sleep homeostasis during waking and sleep, the electroencephalogram of eight young males was recorded intermittently during a 40-h waking episode, as well as during baseline and recovery sleep. In th
Autor:
Alexander A. Borbély, Corinne Roth, Peter Achermann, Alfred Buck, Luca A. Finelli, Hans-Peter Landolt
Publikováno v:
Journal of Sleep Research. 9:175-183
To study the role of GABA-ergic mechanisms in sleep regulation, the combined action of 40 h sleep deprivation and either 20 mg zolpidem or placebo on the sleep electroencephalogram (EEG) were investigated by quantitative EEG analysis in eight young m
Autor:
Peter Achermann, Corinne Roth, Alfred Buck, Alexander A. Borbély, Hans-Peter Landolt, Luca A. Finelli, Thomas Berthold
Publikováno v:
Journal of Sleep Research. 9:161-173
Changes in the functional organization of the brain during the course of sleep and waking are reflected by different patterns of regional cerebral blood flow (rCBF). To investigate the effect of the hypnotic zolpidem, a benzodiazepine receptor agonis
Autor:
Luca A. Finelli, Jacqueline Ros, Jessie Moreau, Niels Andreasen, Georges Imbert, Marie-Emmanuelle Riviere, Peter Quarg, Ana Graf, Angelika Caputo, Jeffrey Sevigny, Bengt Winblad
Publikováno v:
Alzheimer's & Dementia. 6
Publikováno v:
Alzheimer's & Dementia. 5