Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Luca, Sardo"'
Autor:
Guoxin Wu, Samuel H. Keller, Luca Sardo, Brian Magliaro, Paul Zuck, Carl J. Balibar, Claire Williams, Liuliu Pan, Mark Gregory, Kathy Ton, Jill Maxwell, Carol Cheney, Tom Rush, Bonnie J. Howell
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Background Latency remains a major obstacle to finding a cure for HIV despite the availability of antiretroviral therapy. Due to virus dormancy, limited biomarkers are available to identify latent HIV-infected cells. Profiling of individual
Externí odkaz:
https://doaj.org/article/01fa0f698e854c8984b8df83b5423713
Autor:
Aidan McGraw, Grace Hillmer, Stefania M. Medehincu, Yuta Hikichi, Sophia Gagliardi, Kedhar Narayan, Hasset Tibebe, Dacia Marquez, Lilia Mei Bose, Adleigh Keating, Coco Izumi, Kevin Peese, Samit Joshi, Mark Krystal, Kathleen L. DeCicco-Skinner, Eric O. Freed, Luca Sardo, Taisuke Izumi
Publikováno v:
Viruses, Vol 16, Iss 9, p 1423 (2024)
HIV-1 virion maturation is an essential step in the viral replication cycle to produce infectious virus particles. Gag and Gag-Pol polyproteins are assembled at the plasma membrane of the virus-producer cells and bud from it to the extracellular comp
Externí odkaz:
https://doaj.org/article/80d24a174b6e4afea42006719a85adfb
Autor:
Tram M. Ta, Sajjaf Malik, Elizabeth M. Anderson, Amber D. Jones, Jocelyn Perchik, Maryann Freylikh, Luca Sardo, Zackary A. Klase, Taisuke Izumi
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Although HIV-1 replication can be efficiently suppressed to undetectable levels in peripheral blood by combination antiretroviral therapy (cART), lifelong medication is still required in people living with HIV (PLWH). Life expectancies have been exte
Externí odkaz:
https://doaj.org/article/956b1fe292e64bb48ec61e1e07280e61
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b24e83c0a3e74ebba40ad3a263ca0d9c
Autor:
Anamaria D. Sarca, Luca Sardo, Hirofumi Fukuda, Hiroyuki Matsui, Kotaro Shirakawa, Kazuki Horikawa, Akifumi Takaori-Kondo, Taisuke Izumi
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
HIV-1 infectivity is achieved through virion maturation. Virus particles undergo structural changes via cleavage of the Gag polyprotein mediated by the viral protease, causing the transition from an uninfectious to an infectious status. The majority
Externí odkaz:
https://doaj.org/article/385ded9ba1f14fd0ad1999b8cb4ba1a1
Autor:
Kenneth Chen, Thienlong Phan, Angel Lin, Luca Sardo, Anthony R Mele, Michael R Nonnemacher, Zachary Klase
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230563 (2020)
Despite antiretroviral therapy human immunodeficiency virus type-1 (HIV-1) infection results in neuroinflammation of the central nervous system that can cause HIV-associated neurocognitive disorders (HAND). The molecular mechanisms involved in the de
Externí odkaz:
https://doaj.org/article/ab94f14817b34edc8db989ab72fd19aa
Autor:
Hirofumi Fukuda, Songling Li, Luca Sardo, Jessica L. Smith, Kazuo Yamashita, Anamaria D. Sarca, Kotaro Shirakawa, Daron M. Standley, Akifumi Takaori-Kondo, Taisuke Izumi
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
APOBEC3G (A3G) is a cellular protein that inhibits HIV-1 infection through virion incorporation. The interaction of the A3G N-terminal domain (NTD) with RNA is essential for A3G incorporation in the HIV-1 virion. The interaction between A3G-NTD and R
Externí odkaz:
https://doaj.org/article/88d0bc551ed843f195c8f8cf7c43014d
Autor:
Weam Elbezanti, Angel Lin, Alexis Schirling, Alexandria Jackson, Matthew Marshall, Rachel Van Duyne, Frank Maldarelli, Luca Sardo, Zachary Klase
Publikováno v:
Viruses, Vol 12, Iss 2, p 191 (2020)
Antiretroviral therapy (ART) lowers human immunodeficiency virus type 1 (HIV-1) viral load to undetectable levels, but does not eliminate the latent reservoir. One of the factors controlling the latent reservoir is transcriptional silencing of the in
Externí odkaz:
https://doaj.org/article/4c9ea35137d24e1e9f48884d828e0155
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89951 (2014)
Tomato yellow leaf curl Sardinia virus (TYLCSV), a DNA virus belonging to the genus Begomovirus, causes severe losses in tomato crops. It infects only a limited number of cells in the vascular tissues, making difficult to detect changes in host gene
Externí odkaz:
https://doaj.org/article/a518d9e953984c058285a9a05c930f6d
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2175
Modifications in chromatin structure are traditionally monitored by biochemical assays that provide average measurements of static events in a population of cells. Microscopy provides a method by which single cells or nuclei can be observed. Traditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45fdc5eaaebd206c6475f1be252d7435
https://pubmed.ncbi.nlm.nih.gov/32681481
https://pubmed.ncbi.nlm.nih.gov/32681481