Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Luc Vander Elst"'
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/5fb876a1da9e47f08a0fd9bc363d9a5a
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Autoreactive CD4+ T cells recognizing islet-derived antigens play a primary role in type 1 diabetes. Specific suppression of such cells therefore represents a strategic target for the cure of the disease. We have developed a methodology by which CD4+
Externí odkaz:
https://doaj.org/article/33678bf5935c483ca04a8d40e543ce5e
Autor:
Philipp Starkl, Luc Vander Elst, Caroline Stremnitzer, Jean-Marie Saint-Remy, Tamara Kopp, Julia Wallmann, Isabella Pali-Schöll, Krisztina Szalai, Erika Jensen-Jarolim, Anna Lukschal
Publikováno v:
Experimental Dermatology
The major house dust mite allergens Der p 1 and Der p 2 are prevalent inducers of eczema. Der p 1 is a cysteine protease disrupting epithelial barriers, whereas Der p 2 functionally mimics the LPS-binding compound MD-2 within the TLR4 complex. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbcf879507f534f0e25aef1c813eff36
https://doi.org/10.1111/exd.12015
https://doi.org/10.1111/exd.12015
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 7 (2016)
Frontiers in Immunology, Vol. 7, p. 67 [1-10] (2016)
Frontiers in Immunology, Vol 7 (2016)
Frontiers in Immunology, Vol. 7, p. 67 [1-10] (2016)
Autoreactive CD4(+) T cells recognizing islet-derived antigens play a primary role in type 1 diabetes. Specific suppression of such cells therefore represents a strategic target for the cure of the disease. We have developed a methodology by which CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30511c1b4e785bd918530490ca47668b
https://pubmed.ncbi.nlm.nih.gov/30034402
https://pubmed.ncbi.nlm.nih.gov/30034402
Publikováno v:
Frontiers in Immunology, Vol. 6, no.0, p. 449 (2015)
Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology
Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology
Abrogating an unwanted immune response toward a specific antigen without compromising the entire immune system is a hoped-for goal in immunotherapy. Instead of manipulating dendritic cells and suppressive regulatory T cells, depleting effector T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a208edb70e0d7cf4e41ab9de87c46788
https://hdl.handle.net/2078.1/165445
https://hdl.handle.net/2078.1/165445
Publikováno v:
The Journal of Immunology. 169:2430-2435
The use of T cell epitope-containing peptides for the induction of anergy in allergen sensitization is limited by genetic restriction that could be circumvented by using universally immunogenic epitopes. We attempted to identify such epitopes on Derm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efbbe016d3f3a6617c494bc7de0e580
https://doi.org/10.4049/jimmunol.169.5.2430
https://doi.org/10.4049/jimmunol.169.5.2430
Publikováno v:
European Journal of Immunology. 30:291-299
Peptides containing major T cell epitopes have the capacity to induce T cell anergy and have therefore been proposed for the treatment of allergic and autoimmune diseases. Such peptides should not be immunogenic, i. e. should not contain a B cell rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fbe41dd4acb1ec82bd860dedc239d37
https://doi.org/10.1002/1521-4141(200001)30:1<291::aid-immu291>3.0.co
https://doi.org/10.1002/1521-4141(200001)30:1<291::aid-immu291>3.0.co
Autor:
Jos Vermylen, Marc Hoylaerts, Kathelijne Peerlinck, Marleen Bakkus, Abdellah Benhida, Kris Thielemans, Marc Jacquemin, Luc Vander Elst, B Desqueper, Jean-Marie Saint-Remy, Jean Guy G. Gilles, Jef Arnout
Publikováno v:
Blood. 92:496-506
The development of an immune response towards factor VIII (fVIII) remains a major complication for hemophilia A patients receiving fVIII infusions. The design of a specific therapy to restore unresponsiveness to fVIII has been hampered by the diversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b4d828442c087f9f980d3e27ec6bb41
https://doi.org/10.1182/blood.v92.2.496
https://doi.org/10.1182/blood.v92.2.496
Autor:
Marc G. Jacquemin, Benoı̂t G. Desqueper, Abdellah Benhida, Luc Vander Elst, Marc F. Hoylaerts, Marleen Bakkus, Kris Thielemans, Jef Arnout, Kathelijne Peerlinck, Jean Guy G. Gilles, Jos Vermylen, Jean-Marie R. Saint-Remy
Publikováno v:
Blood. 92:496-506
The development of an immune response towards factor VIII (fVIII) remains a major complication for hemophilia A patients receiving fVIII infusions. The design of a specific therapy to restore unresponsiveness to fVIII has been hampered by the diversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbbf52c3292f75ee12567976590ea86c
https://doi.org/10.1182/blood.v92.2.496.414k16_496_506
https://doi.org/10.1182/blood.v92.2.496.414k16_496_506
Publikováno v:
International Archives of Allergy and Immunology. 124:383-385
Background: Major allergens could represent a ‘port of entry’ to allergen polysensitization. The immunogenic properties of Der p 2 T cell epitopes were evaluated to test this hypothesis. Material and Methods: T cells were obtained from regional l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf240717edcb852838d9e6ed3370cab5
https://doi.org/10.1159/000053764
https://doi.org/10.1159/000053764