Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Luc Van Hijfte"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 160-176 (2019)
Targeting the “undruggable” proteome remains one of the big challenges in drug discovery. Recent innovations in the field of targeted protein degradation and manipulation of the ubiquitin-proteasome system open up new therapeutic approaches for d
Externí odkaz:
https://doaj.org/article/db4f8ae381d842e897739ae21a36e599
Publikováno v:
ARKIVOC, Vol 2010, Iss 8, Pp 126-159 (2010)
Externí odkaz:
https://doaj.org/article/54bb7ffbc5a5437e8973519e7113201d
Publikováno v:
ARKIVOC, Vol 2010, Iss 8, Pp 27-40 (2010)
Externí odkaz:
https://doaj.org/article/1c077824e33b4982871061a6a77c72ac
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 160-176 (2019)
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 160-176 (2019)
Targeting the “undruggable” proteome remains one of the big challenges in drug discovery. Recent innovations in the field of targeted protein degradation and manipulation of the ubiquitin-proteasome system open up new therapeutic approaches for d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55f14af58eb8c9f473abe858d099813
https://doi.org/10.1016/j.csbj.2019.01.006
https://doi.org/10.1016/j.csbj.2019.01.006
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2017, 12 (12), pp.862-871. ⟨10.1002/cmdc.201700336⟩
ChemMedChem, Wiley-VCH Verlag, 2017, 12 (12), pp.862-871. ⟨10.1002/cmdc.201700336⟩
Outstanding Medchem in France: Guest editors Janos Sapi, Luc Van Hjfte, and Patrick Dallemagne look back at the 52nd International Conference on Medicinal Chemistry (RICT 2016) held in Caen, France. They discuss the history of the French Medicinal Ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0572956a6811ed877305f8f903363499
https://hal.archives-ouvertes.fr/hal-02043722
https://hal.archives-ouvertes.fr/hal-02043722
Autor:
Rufine Akué-Gédu, Daniel Couturier, Luc Van Hijfte, Anne Bourry, Gerard Charles Sanz, Jean-Pierre Hénichart, Benoît Rigo
Publikováno v:
Tetrahedron. 68:5644-5654
The synthesis of new condensed indolizinediones derived from pyroglutamic acid is described. The Semmler–Wolff transposition of the oxime of these ketones leads to fused dihydro-1,5-naphthyridinones. Easy introduction of side amino chains indicates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::614fa5ead0aa5eceeade3c944ab5736c
https://doi.org/10.1016/j.tet.2012.04.056
https://doi.org/10.1016/j.tet.2012.04.056
Autor:
Anne Bourry, Rufine Akué-Gédu, Luc Van Hijfte, Jean-Pierre Hénichart, Gerard Charles Sanz, Benoît Rigo, Daniel Couturier
Publikováno v:
Tetrahedron. 68:1117-1127
The synthesis of some condensed indolizinediones derived from pyroglutamic acid is described. Treatment of these ketones in HCl, HBr or MeONa/MeOH furnished aryl propionic acid derivatives. During the ketone transformations, two sequential processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5dad8e6df33e251199272edd3b45b28
https://doi.org/10.1016/j.tet.2011.11.071
https://doi.org/10.1016/j.tet.2011.11.071
Publikováno v:
ARKIVOC, Vol 2010, Iss 8, Pp 126-159 (2010)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a473f02530ab0f163adad34790908cf5
https://doi.org/10.3998/ark.5550190.0011.812
https://doi.org/10.3998/ark.5550190.0011.812
Autor:
Luc Van Hijfte, Thomas Hameury, Janine Cossy, Véronique Bellosta, Jérôme Emile Georges Guillemont
Publikováno v:
European Journal of Organic Chemistry. 2010:607-610
The α-ketol rearrangement of tertiary α-hydroxy esters induced by LiAlH 4 /acid treatment provides α-hydroxy ketones in good yields and high diastereoselectivity. A mechanism is proposed for this reaction as well as a model to explain the diastere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::613ce6870757a74d57d04f4e8a07c64f
https://doi.org/10.1002/ejoc.200901202
https://doi.org/10.1002/ejoc.200901202
Autor:
Thomas Hameury, Luc Van Hijfte, Jérôme Emile Georges Guillemont, Véronique Bellosta, Janine Cossy
Publikováno v:
Organic Letters. 11:2397-2400
A diastereodivergent addition of allenylzincs to aryl glyoxylates was observed depending on the method used for the preparation of the allenylzinc reagent. The allenylzincs were prepared from propargylic benzoates in the presence of a palladium catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377a75adc838314c7da924e2e7b3538d
https://doi.org/10.1021/ol900494g
https://doi.org/10.1021/ol900494g