Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Luc Van Der Steen"'
Autor:
Ronald K. Russell, Yongzheng Zhang, Marc Verbeek, Michael Reuman, Zhihua Sui, Hilde Vanbaelen, Christopher A. Teleha, Shawn Branum, James C. Lanter, Fawzy Nagy E, Fu-An Kang, Luc Van Der Steen, Michael Kolpak, Michael P. Winters, Derek A. Beauchamp, Gregory C. Leo
Publikováno v:
Organic Process Research & Development. 18:1630-1640
The preparation of a chemokine receptor type 2 (CCR-2) antagonist bearing a cyclopenta[b]furan core is described on a 600 g scale. Compared to our previously reported synthesis of the all-carbon core CCR-2 antagonist with a similar peripheral 3-metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6e2ea61a6b3e2fe6f4999868e3c1c57
https://doi.org/10.1021/op500266w
https://doi.org/10.1021/op500266w
Autor:
Shawn Branum, Fawzy Nagy E, Christopher A. Teleha, Luc Van Der Steen, Mark J. Wall, Derek A. Beauchamp, Michael Reuman, Marc Verbeek, Michael Kolpak, Zhihua Sui, Chaozhong Cai, Gregory C. Leo, Ronald K. Russell, Yongzheng Zhang, Fu-An Kang, Hilde Vanbaelen
Publikováno v:
Organic Process Research & Development. 18:1622-1629
The preparation of a novel chemokine receptor type 2 (CCR-2) antagonist is described on a 135 g scale. The synthesis of an all-carbon bicyclic core was accomplished using a radical cyclization strategy using chiral precursors, wherein elaboration led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30ed40727f516d73f0e1e4e53e8301d9
https://doi.org/10.1021/op500265z
https://doi.org/10.1021/op500265z