Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Luc VAN Gaal"'
Autor:
Evelien Van Dijck, Sara Diels, Erik Fransen, Tycho Canter Cremers, An Verrijken, Eveline Dirinck, Alexander Hoischen, Geert Vandeweyer, Wim Vanden Berghe, Luc Van Gaal, Sven Francque, Wim Van Hul
Publikováno v:
Antioxidants, Vol 13, Iss 9, p 1051 (2024)
The paraoxonase (PON) gene family (including PON1, PON2, and PON3), is known for its anti-oxidative and anti-inflammatory properties, protecting against metabolic diseases such as obesity and metabolic dysfunction-associated steatotic liver disease (
Externí odkaz:
https://doaj.org/article/3610f4d5206345fe9f8499759c900757
Autor:
Ning Liang, Anastasius Damdimopoulos, Saioa Goñi, Zhiqiang Huang, Lise-Lotte Vedin, Tomas Jakobsson, Marco Giudici, Osman Ahmed, Matteo Pedrelli, Serena Barilla, Fawaz Alzaid, Arturo Mendoza, Tarja Schröder, Raoul Kuiper, Paolo Parini, Anthony Hollenberg, Philippe Lefebvre, Sven Francque, Luc Van Gaal, Bart Staels, Nicolas Venteclef, Eckardt Treuter, Rongrong Fan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Dysregulation of PPARα dependent fatty acid oxidation promotes hepatic steatosis. Here the authors show that GPS2 inhibits PPARα activity and that ablation of GPS2 ameliorates hepatic steatosis in mice.
Externí odkaz:
https://doaj.org/article/90508a91d07f4ebf99f099ffd68ebc8f
Autor:
Guillaume Grzych, Oscar Chávez-Talavera, Amandine Descat, Dorothée Thuillier, An Verrijken, Mostafa Kouach, Vanessa Legry, Hélène Verkindt, Violeta Raverdy, Benjamin Legendre, Robert Caiazzo, Luc Van Gaal, Jean-Francois Goossens, Réjane Paumelle, Sven Francque, François Pattou, Joel T. Haas, Anne Tailleux, Bart Staels
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100222- (2021)
Background & Aims: Plasma bile acids (BAs) have been extensively studied as pathophysiological actors in non-alcoholic steatohepatitis (NASH). However, results from clinical studies are often complicated by the association of NASH with type 2 diabete
Externí odkaz:
https://doaj.org/article/86f4e08dfca4419c8dc1e4b25ab23c55
Autor:
Nina Hermans, Anastasia Van der Auwera, Annelies Breynaert, Annelies Verlaet, Tess De Bruyne, Luc Van Gaal, Luc Pieters, Veronique Verhoeven
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background Metabolic syndrome (MetS) refers to clustered cardiovascular risk factors (abdominal obesity, pre-diabetes, high blood pressure, dyslipidaemia). Therapies targeting oxidative stress may delay progression to atherosclerosis and dia
Externí odkaz:
https://doaj.org/article/a1703d0ea42c449286463fbeb4d9d1ac
Autor:
Wim Verlinden, Eugénie Van Mieghem, Laura Depauw, Thomas Vanwolleghem, Luisa Vonghia, Jonas Weyler, Ann Driessen, Dirk Callens, Laurence Roosens, Eveline Dirinck, An Verrijken, Luc Van Gaal, Sven Francque
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 546 (2020)
The incidence of non-alcoholic fatty liver disease (NAFLD) is rising across the globe, with the presence of steatohepatitis leading to a more aggressive clinical course. Currently, the diagnosis of non-alcoholic steatohepatitis (NASH) is based on his
Externí odkaz:
https://doaj.org/article/05ac3ce96c48437f99bd6ec6e195f348
Autor:
Kaat Kehoe, Heidi Noels, Wendy Theelen, Emilie De Hert, Shenguan Xu, An Verrijken, Thierry Arnould, Erik Fransen, Nina Hermans, Anne-Marie Lambeir, Per Venge, Luc Van Gaal, Ingrid De Meester
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197603 (2018)
BACKGROUND:Prolyl carboxypeptidase (PRCP) is involved in the regulation of body weight, likely by hydrolysing alpha-melanocyte-stimulating hormone and apelin in the hypothalamus and in the periphery. A link between PRCP protein concentrations in plas
Externí odkaz:
https://doaj.org/article/2dd0dc721c3b40a0b8ef9ddacedea1a4
Autor:
Katrien Clotman, MD, Marcel Twickler, MD, PhD, Eveline Dirinck, MD, PhD, Jan Van Den Brande, MD, Martin Lammens, MD, PhD, Ann Verhaegen, MD, Christophe De Block, MD, PhD, Luc Van Gaal, MD, PhD
Publikováno v:
AACE Clinical Case Reports, Vol 3, Iss 3, Pp e278-e283 (2017)
ABSTRACT: Objective: To describe a unique case of a 61-year-old patient presenting with ectopic Cushing syndrome as a paraneoplastic phenomenon due to adrenocorticotropic hormone (ACTH)-secreting bone metastasis of an olfactory neuroblastoma (ON).Met
Externí odkaz:
https://doaj.org/article/563ee452f7304bed9b7b53b63b519210
Autor:
Eva Philipse, Ester Philipse, Theodorus Twickler, Amaryllis Van Craenenbroeck, Marie Madeleine Couttenye, Luc Van Gaal
Publikováno v:
Case Reports in Nephrology, Vol 2017 (2017)
A female hemodialysis patient with galactorrhea due to hyperprolactinemia was treated with different dialysis modalities to assess the effect on prolactin levels. A single session of both high-flux hemodialysis and hemodiafiltration resulted in decre
Externí odkaz:
https://doaj.org/article/944c3ffabb504ba1a2b71b33bc693f07
Publikováno v:
Journal of Clinical & Translational Endocrinology, Vol 1, Iss 2, Pp 31-37 (2014)
Objective: To compare the efficacy and safety of the once-daily prandial glucagon-like peptide-1 receptor agonist lixisenatide with the dipeptidyl peptidase-4 inhibitor sitagliptin in patients aged
Externí odkaz:
https://doaj.org/article/74aa8d68fbc84b3cae3cc7f257f99b95
Autor:
Annelies Van Eyck, Kim Van Hoorenbeeck, Benedicte Y. De Winter, Luc Van Gaal, Wilfried De Backer, Stijn L. Verhulst
Publikováno v:
ERJ Open Research, Vol 2, Iss 4 (2016)
Obstructive sleep apnoea (OSA), common in children with obesity, is associated with cardiovascular morbidity. Autonomic dysfunction has been suggested to be a key player in the development of these complications. We investigated the relationship betw
Externí odkaz:
https://doaj.org/article/455f6ec59d58449c84b0e09042414400