Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Luc P. Balant"'
Publikováno v:
AAPS PharmSci. 6:56-67
A 2-day workshop on “Physiologically Based Pharmacokinetics (PBPK) in Drug Development and Regulatory Science” came to a successful conclusion on May 30, 2002, in Washington, DC. More than 120 international participants from the environmental and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9bf4c271f16a97caef57aade2701c85
https://doi.org/10.1208/ps060106
https://doi.org/10.1208/ps060106
Autor:
Luc P. Balant, Marianne Gex-Fabry, Gilles Bertschy, Jean-Luc Veuthey, A. E. Balant-Gorgia, Serge Rudaz
Publikováno v:
European Journal of Clinical Pharmacology, Vol. 59, No 12 (2004) pp. 883-91
OBJECTIVE: Early clinical response to antidepressant treatment is an important therapeutic goal, considering the psychological, social and economic consequences of depression. The aim of the present study was to investigate the relationship between t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9219b9f5820a36e2742ae0a7a4747b1
https://doi.org/10.1007/s00228-003-0710-3
https://doi.org/10.1007/s00228-003-0710-3
This book contains the papers from invited lecturers as well as selected contributions presented at the 6th International Meeting on Clinical Pharmacology in Psychiatry (I.M.C.P.P.) held in Geneva, Switzerland, 5-7 June 1991. At this meeting the basi
Autor:
Luc P. Balant
Publikováno v:
Burger's Medicinal Chemistry and Drug Discovery
This review concentrates on prodrugs designed by pharmaceutical chemists to overcome biopharmaceutical or pharmacokinetic (essentially metabolic) problems encountered with active principles. The investigations presented in this review illustrate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d98d875e4794ecd96ebd099b846a45d8
https://doi.org/10.1002/0471266949.bmc034
https://doi.org/10.1002/0471266949.bmc034
Publikováno v:
Drug Safety. 24:947-959
Drug-drug interactions can be associated with patient morbidity due to either increased toxicity or a potentially ineffective concentration. Because interactions cannot always be anticipated during drug development and actual patients receiving a dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb2fc9ed06ea07d0d2c6dd831168499
https://doi.org/10.2165/00002018-200124130-00002
https://doi.org/10.2165/00002018-200124130-00002
Autor:
Luc P. Balant, Marianne Gex-Fabry
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 50:13-26
With the advancement of both biological and computer sciences, new drug development faces the challenge to integrate a huge amount of knowledge accumulated from the very early quantitative structure-activity relationship investigations of the candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a7919d2e12268f51daca0cca622108
https://doi.org/10.1016/s0939-6411(00)00083-7
https://doi.org/10.1016/s0939-6411(00)00083-7
Autor:
E A Balant-Gorgia, Luc P. Balant
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 38:47-52
Introductory remarks: Discussing the inter-ethnicity of kinetics and actions of drugs is fraught with terminology problems. It is, however, generally accepted that ethnicity covers the influences of factors genetically and culturally transmitted. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b07b3d4457eb84e51431f27cc5d284b
https://doi.org/10.5414/cpp38047
https://doi.org/10.5414/cpp38047
Publikováno v:
Therapeutic Drug Monitoring. 21:105-115
Because of the enormous gap between premarketing studies in physically healthy subjects and clinical practice in patients, the present study reconsidered interindividual variability factors affecting risperidone concentrations under routine therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c16dd6ffb73d5e9c6ab9ab5d83fe0d0
https://doi.org/10.1097/00007691-199902000-00017
https://doi.org/10.1097/00007691-199902000-00017
Autor:
Peter G. Welling, Luc P. Balant
The author of this Foreword has recently retired after spending 25 years in academia and 15 years in the pharmaceutical industry. Most of this time has been spent following and, hopefully in some instances, contributing to advancement of the discipli
Autor:
Marianne Gex-Fabry, Luc P. Balant, Eric Doelker, Ewart Thomas Cole, Pierre Buri, Eric Allémann, Nathalie Rouge
Publikováno v:
Pharmaceutica Acta Helvetiae. 73:81-87
The purpose of this study was to evaluate the possible advantages of floating and high-density dosage forms and their influence on pharmacokinetic parameters. Atenolol was chosen as a model drug because of its poor absorption in the lower gastrointes
Externí odkaz:
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https://doi.org/10.1016/s0031-6865(97)00050-2
https://doi.org/10.1016/s0031-6865(97)00050-2