Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Luc Geeraert"'
Publikováno v:
Annual Review of Medicine. 59:487-501
The success of highly active antiretroviral therapy (HAART) for HIV-1 infection has sparked interest in mechanisms by which the virus can persist despite effectively suppressive therapy. Latent HIV-1 reservoirs established early during infection not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdcd9ec5085ed91c5b95e0fc0117d77
https://doi.org/10.1146/annurev.med.59.062806.123001
https://doi.org/10.1146/annurev.med.59.062806.123001
This chapter discusses the non-nucleoside reverse transcriptase inhibitors (NNRTI), which is a valuable component of first-line highly active antiretroviral therapy (HAART) today. Reverse transcriptase (RT) is an essential enzyme in the replication c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7651bebb5ccd325c02d2f801bd7fe7d9
https://doi.org/10.1128/9781555815493.ch3
https://doi.org/10.1128/9781555815493.ch3
Publikováno v:
Biochemical Journal. 327:125-132
Ceramide has been suggested to be a potent bioactive lipid involved in cell growth, differentiation and apoptosis. Its precursor, dihydroceramide, does not affect these processes. The truncated dihydroceramide analogues N-hexanoyl-[4,5-3H]-D-erythro-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba945ed2e7e9bbb7eeb9da14adb41ca
https://doi.org/10.1042/bj3270125
https://doi.org/10.1042/bj3270125
Publikováno v:
Analogue-Based Drug Discovery II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::113515ba2c78e92954bdffa0abe0c939
https://doi.org/10.1002/9783527630035.ch17
https://doi.org/10.1002/9783527630035.ch17
Autor:
Catherine Causeret, Paul P. Van Veldhoven, Gerd Van der Hoeven, Luc Geeraert, Guy P. Mannaerts
Publikováno v:
Lipids. 35(10)
The introduction of the double bond in the sphingoid backbone of sphingolipids occurs at the level of dihydroceramide via an NADPH-dependent desaturase, as discovered in permeabilized rat hepatocytes. In the rat, the enzyme activity, which has now be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274fd2ad5a8abcd3ab7d64feaf282be2
https://pubmed.ncbi.nlm.nih.gov/11104018
https://pubmed.ncbi.nlm.nih.gov/11104018