Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Luc Demange"'
Publikováno v:
Molecules, Vol 29, Iss 12, p 2716 (2024)
The journey of drug discovery (DD) has evolved from ancient practices to modern technology-driven approaches, with Artificial Intelligence (AI) emerging as a pivotal force in streamlining and accelerating the process. Despite the vital importance of
Externí odkaz:
https://doaj.org/article/9780fad191b1478a82974e1d66efb3b9
Autor:
Aurore Dumond, Etienne Brachet, Jérôme Durivault, Valérie Vial, Anna K. Puszko, Yves Lepelletier, Christopher Montemagno, Marina Pagnuzzi-Boncompagni, Olivier Hermine, Christiane Garbay, Nathalie Lagarde, Matthieu Montes, Luc Demange, Renaud Grépin, Gilles Pagès
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Despite the improvement of relapse-free survival mediated by anti-angiogenic drugs like sunitinib (Sutent®), or by combinations of anti-angiogenic drugs with immunotherapy, metastatic clear cell Renal Cell Carcinoma (mccRCC) rema
Externí odkaz:
https://doaj.org/article/4462a16912a7494aaca4c614ed37b5dd
Autor:
Marie Fabre, Lou Mateo, Diana Lamaa, Stéphanie Baillif, Gilles Pagès, Luc Demange, Cyril Ronco, Rachid Benhida
Publikováno v:
Molecules, Vol 27, Iss 16, p 5089 (2022)
Age-related macular degeneration (AMD) was described for the first time in the 1840s and is currently the leading cause of blindness for patients over 65 years in Western Countries. This disease impacts the eye’s posterior segment and damages the m
Externí odkaz:
https://doaj.org/article/801ad72ccc4648a6b6ef0972087a45af
Publikováno v:
ARKIVOC, Vol 2017, Iss 4, Pp 51-62 (2017)
Externí odkaz:
https://doaj.org/article/8665bc2708d245798b47116374b17643
Autor:
Sandrine Houzé, Nha-Thu Hoang, Olivier Lozach, Jacques Le Bras, Laurent Meijer, Hervé Galons, Luc Demange
Publikováno v:
Molecules, Vol 19, Iss 9, Pp 15237-15257 (2014)
In Africa, malaria kills one child each minute. It is also responsible for about one million deaths worldwide each year. Plasmodium falciparum, is the protozoan responsible for the most lethal form of the disease, with resistance developing against t
Externí odkaz:
https://doaj.org/article/679b402f375741dfa47352f91038f5d8
Publikováno v:
Molecules, Vol 21, Iss 8, p 1032 (2016)
This review describes the recent advances in the microwave-assisted synthesis of 7-membered and larger heterocyclic compounds. Several types of reaction for the cyclization step are discussed: Ring Closing Metathesis (RCM), Heck and Sonogashira react
Externí odkaz:
https://doaj.org/article/09f7478cb5794665a10a3a44fbfad377
Publikováno v:
Molecules, Vol 21, Iss 4, p 492 (2016)
This review describes the formation of six-membered heterocyclic compounds and their fused analogues under microwave activation using modern organic transformations including cyclocondensation, cycloaddition, multicomponents and other modular reactio
Externí odkaz:
https://doaj.org/article/8190761d52194709941a69195ddc93a4
Autor:
Krystel, El Hage, Giovanni, Ribaudo, Louis, Lagardère, Alberto, Ongaro, Philippe H, Kahn, Luc, Demange, Jean-Philip, Piquemal, Giuseppe, Zagotto, Nohad, Gresh
Publikováno v:
Journal of chemical information and modeling. 62(24)
GC-rich sequences are recurring motifs in oncogenes and retroviruses and could be targeted by noncovalent major-groove therapeutic ligands. We considered the palindromic sequence d(G
Autor:
Michele De Franco, Luc Demange, Giovanni Ribaudo, Giuseppe Zagotto, Nohad Gresh, Emmanuelle Braud, Alberto Ongaro, Christiane Garbay, Mélanie Etheve-Quelquejeu
Publikováno v:
New Journal of Chemistry. 44:3624-3631
In oncology, some DNA intercalating agents have been used in chemotherapy for years to eradicate cancer cells, but these drugs generally suffer from a lack of selectivity for malignant tissues and consequently induce major side-effects. We report her
Autor:
Nathalie Lagarde, Marina Pagnuzzi-Boncompagni, Valérie Vial, Matthieu Montes, Christiane Garbay, Gilles Pagès, Aurore Dumond, Jérôme Durivault, Olivier Hermine, Yves Lepelletier, Renaud Grépin, Anna K. Puszko, Etienne Brachet, Christopher Montemagno, Luc Demange
Publikováno v:
Journal of experimental & clinical cancer research
Journal of experimental & clinical cancer research, 2021, 40, pp.33. ⟨10.1186/s13046-021-01832-x⟩
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Journal of Experimental & Clinical Cancer Research : CR
Journal of experimental & clinical cancer research, BioMed Central, 2021, 40, pp.33. ⟨10.1186/s13046-021-01832-x⟩
Journal of experimental & clinical cancer research, 2021, 40, pp.33. ⟨10.1186/s13046-021-01832-x⟩
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Journal of Experimental & Clinical Cancer Research : CR
Journal of experimental & clinical cancer research, BioMed Central, 2021, 40, pp.33. ⟨10.1186/s13046-021-01832-x⟩
Background Despite the improvement of relapse-free survival mediated by anti-angiogenic drugs like sunitinib (Sutent®), or by combinations of anti-angiogenic drugs with immunotherapy, metastatic clear cell Renal Cell Carcinoma (mccRCC) remain incura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d677e8e8583e1e97aec4253f46f80f8e
https://doi.org/10.1186/s13046-021-01832-x
https://doi.org/10.1186/s13046-021-01832-x