Výsledky vyhledávání - "Luc Dannhoffer"

Interplay between hypoactivity, muscle properties and motor command:How to escape the vicious deconditioning circle?

Autor: Erwan Dupont, Caroline Cieniewski-Bernard, Marie-Hélène Canu, Jacques-Olivier Coq, Bruno Bastide, Laurence Stevens, Luc Dannhoffer, Julie Fourneau

Publikováno v: Annals of Physical and Rehabilitation Medicine
Annals of Physical and Rehabilitation Medicine, Elsevier Masson, 2019, 62 (2), pp.122-127. ⟨10.1016/j.rehab.2018.09.009⟩
Annals of Physical and Rehabilitation Medicine, 2019, 62 (2), pp.122-127. ⟨10.1016/j.rehab.2018.09.009⟩

Activity-dependent processes addressing the central nervous system (CNS) and musculoskeletal structures are critical for maintaining motor performance. Chronic reduction in activity, whether due to a sedentary lifestyle or extended bed rest, results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da19d6f66371926824dc53e0eb246e27
http://hdl.handle.net/20.500.12210/39349

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Stimulation of salivary secretion in vivo by CFTR potentiators in Cftr+/+ and Cftr−/− mice

Autor: Christian Rogier, Yvette Mettey, Sabrina Noël, Luc Dannhoffer, Martina Wilke, Hugo DeJonge, Pierre Olivier Strale, Frédéric Becq

Publikováno v: Journal of Cystic Fibrosis, 7(2), 128-133. Elsevier
Journal of Cystic Fibrosis
Journal of Cystic Fibrosis, Elsevier, 2008, 7 (2), pp.128-133. ⟨10.1016/j.jcf.2007.06.005⟩

Background: Physiologically, salivary secretion is controlled by cholinergic and adrenergic pathways but the role of ionic channels in this process is not yet clearly understood. In cystic fibrosis (CF), most exocrine glands failed to response to bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c84529e7bbceaf083291500fd3724e

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A functional tandem between transient receptor potential canonical channels 6 and calcium-dependent chloride channels in human epithelial cells

Autor: Fabrice Antigny, Caroline Norez, Luc Dannhoffer, Clarisse Vandebrouck, Frédéric Becq, Christophe Jayle, J. Bertrand, Laura Vachel

Publikováno v: European journal of pharmacology. 765

TRPC6 plays important human physiological functions, notably in artery and arterioles constriction, in regulation of vascular volume and in bronchial muscle constriction. It is implicated in pulmonary hypertension, cardiovascular disease, and focal s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35cab66792e3da10ddd8f139a7593a2e
https://pubmed.ncbi.nlm.nih.gov/26265544

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Effect of nitric oxide on epithelial ion transports in noncystic fibrosis and cystic fibrosis human proximal and distal airways

Autor: Anh Tuan Dinh-Xuan, Camille Braun, Luc Dannhoffer, Sabine Blouquit-Laye, Edouard Sage, Thierry Chinet

Publikováno v: American journal of physiology. Lung cellular and molecular physiology. 303(7)

The airways of patients with cystic fibrosis (CF) exhibit decreased nitric oxide (NO) concentrations, which might affect airway function. The aim of this study was to determine the effects of NO on ion transport in human airway epithelia. Primary cul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9f3d3e5a550353fa6f9c5e47ba402e
https://pubmed.ncbi.nlm.nih.gov/22773693

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Stimulation of Wild-Type, F508del- and G551D-CFTR Chloride Channels by Non-Toxic Modified pyrrolo[2,3-b]pyrazine Derivatives

Autor: Mathilde Jollivet, Arnaud Billet, Frédéric Becq, Luc Dannhoffer, Christelle Faveau, Patricia Melin-Heschel

Publikováno v: Frontiers in Pharmacology
Frontiers in Pharmacology, Frontiers, 2011, 2, ⟨10.3389/fphar.2011.00048⟩
Frontiers in Pharmacology, Vol 2 (2011)

International audience; Cystic fibrosis (CF) is a major inherited disorder involving abnormalities of fluid and electrolyte transport in a number of different organs due to abnormal function of cystic fibrosis transmembrane conductance regulator (CFT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff4549110743c334b46b1488c2b0b75

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Transient receptor potential canonical channel 6 links Ca2+ mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis

Autor: J. Bertrand, Clarisse Vandebrouck, Luc Dannhoffer, Pierre Corbi, Frédéric Becq, Fabrice Antigny, Caroline Norez, Christophe Jayle, Dorothée Raveau

Publikováno v: American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society, 2011, 44 (1), pp.83-90. ⟨10.1165/rcmb.2009-0347OC⟩

International audience; In cystic fibrosis (CF), abnormal control of cellular Ca(2+) homeostasis is observed. We hypothesized that transient receptor potential canonical (TRPC) channels could be a link between the abnormal Ca(2+) concentrations in CF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b0977556198296110153d046f956eb
https://hal.archives-ouvertes.fr/hal-00559252

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Identification of a novel water-soluble activator of wild-type and F508del CFTR: GPact-11a

Autor: Benjamin Boucherle, Christophe Jayle, Patricia Melin-Heschel, Luc Dannhoffer, Clarisse Vandebrouck, Christel Routaboul, Jean-Luc Décout, Frédéric Becq, Caroline Norez, J. Bertrand, Arnaud Billet, Marie-Carmen Molina

Publikováno v: European Respiratory Journal
European Respiratory Journal, European Respiratory Society, 2010, 36 (2), pp.311-22. ⟨10.1183/09031936.00122509⟩

International audience; One of the major therapeutic strategy in cystic fibrosis aims at developing modulators of cystic fibrosis transmembrane conductance regulator (CFTR) channels. We recently discovered methylglyoxal alpha-aminoazaheterocycle addu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce55afca02a2f8cb09cddd2bdf8112a
https://pubmed.ncbi.nlm.nih.gov/20110398

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Functional properties of mixed cystic fibrosis and normal bronchial epithelial cell cultures

Autor: Luc Dannhoffer, Agathe Regnier, Thierry Chinet, Sabine Blouquit-Laye

Publikováno v: American journal of respiratory cell and molecular biology. 40(6)

Cystic fibrosis (CF) airway epithelia exhibit altered Cl(-) and Na(+) transport properties and increased IL-8 secretion. In the present study, we examined whether a small proportion of cells with a normal phenotype could normalize the ion transport a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564127b7308875cc672d673e39b5825a
https://pubmed.ncbi.nlm.nih.gov/19011164

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Guanabenz, an α2-selective adrenergic agonist, activates Ca2+-dependent chloride currents in cystic fibrosis human airway epithelial cells

Autor: Marc Blondel, Clarisse Vandebrouck, Frédéric Becq, Luc Dannhoffer, Fabrice Antigny, Caroline Norez

Publikováno v: European Journal of Pharmacology
European Journal of Pharmacology, Elsevier, 2008, 592 (1-3), pp.33-40. ⟨10.1016/j.ejphar.2008.06.103⟩
European Journal of Pharmacology, 2008, 592 (1-3), pp.33-40. ⟨10.1016/j.ejphar.2008.06.103⟩

(IF : 2,37); International audience; In cystic fibrosis respiratory epithelial cells, the absence or dysfunction of the chloride channel CFTR (Cystic Fibrosis Transmembrane conductance Regulator) results in reduced chloride ion transport. In contrast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59ae98ef229c1ba57203b47ac2a9b63
https://hal.archives-ouvertes.fr/hal-00392424

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