Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Luc C. Owono Owono"'
Autor:
Donatus B. Eni, Luc C Owono Owono, Boris D. Bekono, Alfred Ndeme Sona, Eugene Megnassan, Fidele Ntie-Kang
Publikováno v:
Physical Sciences Reviews. 8:457-477
The use of molecular mechanics (MM) in understanding the energy and target of a drug, its structures, and properties has increased recently. This is achieved by the formulation of a simple MM energy equation, which represents the sum of the different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ca76ba2bb0e6fd823bed10ba42c4002
https://doi.org/10.1515/psr-2019-0128
https://doi.org/10.1515/psr-2019-0128
Autor:
Fidele Ntie-Kang, Boris D. Bekono, Wolfgang Sippl, Lydia L. Lifongo, Luc C. Owono Owono, Pascal Amoa Onguéné, Karin Fester
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-35 (2020)
Malaria Journal
Malaria Journal
Background African Traditional Medicine (ATM) is used for the healthcare of about 80% of the rural populations of the continent of Africa. The practices of ATM make use of plant-products, which are known to contain plant-based secondary metabolites o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84eff7e242e5a4e207d5cd7a3d2daaef
http://link.springer.com/article/10.1186/s12936-020-03231-7
http://link.springer.com/article/10.1186/s12936-020-03231-7
Autor:
Pale, Luc C. Owono Owono, Cyril A. Kenfack, Daniel Lissouck, Adoum Issac, Nicodème Djiedeu, William Feudjio Mbogning
Publikováno v:
Journal of food scienceREFERENCES. 86(12)
Fluorescence excitation-emission matrix (EEM) and synchronous scanning fluorescence (SF), coupled with parallel factor (PARAFAC) analysis, principal component analysis (PCA) and Linear discriminant analysis (LDA) methods were used to differentiate 49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e48914d541097b8ec591dd832ba4a3
https://pubmed.ncbi.nlm.nih.gov/34778971
https://pubmed.ncbi.nlm.nih.gov/34778971
Autor:
Luc C. Owono Owono, Flavien A. A. Toze, James A. Mbah, Boris D. Bekono, Joelle Ngo Hanna, Fidele Ntie-Kang, Stefan Günther
Publikováno v:
Physical Sciences Reviews.
In the quest to know why natural products (NPs) have often been considered as privileged scaffolds for drug discovery purposes, many investigations into the differences between NPs and synthetic compounds have been carried out. Several attempts to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eea652f68895471b06a87587686699a
https://doi.org/10.1515/psr-2019-0096
https://doi.org/10.1515/psr-2019-0096
Autor:
Melalie Keita, Eugene Megnassan, Raymond Kre N'Guessan, Luc C. Owono Owono, Stanislav Miertus, Vladimir Frecer, Koffi Charles Kouman
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4730 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 19
International Journal of Molecular Sciences
Volume 20
Issue 19
Background: During the previous decade a new class of benzamide-based inhibitors of 2-trans enoyl-acyl carrier protein reductase (InhA) of Mycobacterium tuberculosis (Mt) with unusual binding mode have emerged. Here we report in silico design and eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7253ae52e66b7b19d1502285d462a39f
https://www.mdpi.com/1422-0067/20/19/4730
https://www.mdpi.com/1422-0067/20/19/4730
Autor:
Eugene Megnassan, Srinivasaraghavan Kannan, Luc C Owono Owono, Kanin Wichapong, Wolfgang Sippl, Fidele Ntie-Kang
Publikováno v:
Mol. BioSyst.. 10:223-239
Recently, the search for new drugs against tuberculosis (TB) has been a hot topic and the search for new inhibitors against validated drug targets and pathways other than those currently targeted by known drugs is suggested to be the most promising w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efedfe0a515d4d53c6968851e969993
https://doi.org/10.1039/c3mb70449a
https://doi.org/10.1039/c3mb70449a
Autor:
Pascal Amoa Onguéné, Luc C. Owono Owono, Michael Scharfe, Simon M. N. Efange, Wolfgang Sippl, Fidele Ntie-Kang, Luc Meva'a Mbaze, Eugene Megnassan
Publikováno v:
RSC Adv.. 4:409-419
We assess the medicinal value and “drug-likeness” of ∼3200 compounds of natural origin, along with some of their derivatives which were obtained through hemisynthesis. In the present study, 376 distinct medicinal plant species belonging to 79 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfa5b00bb15c44608c4c365c461f85ad
https://doi.org/10.1039/c3ra43754j
https://doi.org/10.1039/c3ra43754j
Publikováno v:
Astrophysics and Space Science. 349:171-179
We report on ab initio coupled-cluster calculations of the interaction potential energy surface for the HCNH+–He complex. The aug-cc-pVTZ Gaussian basis, to which is added a set of bond functions placed at mid-distance between HCNH+ center of mass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70860b532c8c9830c792c61cea025748
https://doi.org/10.1007/s10509-013-1600-5
https://doi.org/10.1007/s10509-013-1600-5
Autor:
Fidele Ntie-Kang, Vladimir Frecer, Luc C Owono Owono, Eugene Megnassan, Stanislav Miertus, Melalie Keita
Publikováno v:
Molecular informatics. 34(5)
We report here new chemical structures of predicted nanomolar triclosan-based inhibitors (TCLs) of Mycobacterium tuberculosis enoyl-acyl carrier protein reductase (InhA) virtually proposed by computer-assisted molecular design. 3D models of InhA-TCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b186d753914b11fa975244079c8f54
https://pubmed.ncbi.nlm.nih.gov/27490275
https://pubmed.ncbi.nlm.nih.gov/27490275
Autor:
Simon M. N. Efange, Luc C. Owono Owono, Wolfgang Sippl, Luc Meva'a Mbaze, Nnange Ekwelle, Philip N. Judson, Eugene Megnassan, Lydia L. Lifongo, Fidele Ntie-Kang
Publikováno v:
BMC Complementary and Alternative Medicine
Background In Cameroon herbs are traditionally used to meet health care needs and plans are on the way to integrate traditional medicine in the health care system, even though the plans have not been put into action yet. The country however has a ric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b555233bdc2743f4d1b620d41a9a23e7
https://pubmed.ncbi.nlm.nih.gov/23802859
https://pubmed.ncbi.nlm.nih.gov/23802859