Specific Conditions for Resveratrol Neuroprotection against Ethanol-Induced Toxicity

Autor: Brigitte Gonthier, Nathalie Allibe, Cécile Cottet-Rousselle, Frédéric Lamarche, Laurence Nuiry, Luc Barret

Publikováno v: Journal of Toxicology, Vol 2012 (2012)

Aims. 3,5,4′-Trihydroxy-trans-stilbene, a natural polyphenolic compound present in wine and grapes and better known as resveratrol, has free radical scavenging properties and is a potent protector against oxidative stress induced by alcohol metabol

Externí odkaz: https://doaj.org/article/334d4b6bfd9743eaac0fe01a405b40f2

Protection of PC12 cells from cocaine-induced cell death by inhibiting mitochondrial permeability transition

Autor: Luc Barret, Frederic Lamarche, Eric Fontaine, Cécile Cottet-Rousselle

Publikováno v: Neurochemistry International
Neurochemistry International, Elsevier, 2017, 109, pp.34-40. ⟨10.1016/j.neuint.2017.04.010⟩

International audience; Cocaine abuse induces brain injury and neurodegeneration by a mechanism that has not yet been fully elucidated. Mitochondria play a key role in cell death processes, notably through the opening of the permeability transition p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c023e9c58477b487b67688a1f8ae69
https://hal.univ-grenoble-alpes.fr/hal-01961994

Intérêt d'un logiciel de déconvolution (AMDIS) et d'une détection SIM/SCAN pour le screening toxicologique par CPG-SM

Autor: Hélène Eysseric, Françoise Vincent, Nathalie Allibe-Signorini, Luc Barret, G. Bessard, Séverine Berard

Publikováno v: Annales de Toxicologie Analytique. 20:57-65

Objectif : Cette etude propose une optimisation du screening toxicologique classique en chromatographie gazeuse couplee a une detection en spectrometrie de masse (CPG-SM), en utilisant un logiciel de deconvolution : Automated Mass Spectral Deconvolut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f455525797fe298af5f22303d01d3ed
https://doi.org/10.1051/ata/2009001

ACUTE EXPOSURE OF CULTURED NEURONES TO ETHANOL RESULTS IN REVERSIBLE DNA SINGLE-STRAND BREAKS; WHEREAS CHRONIC EXPOSURE CAUSES LOSS OF CELL VIABILITY

Autor: N. Signorini, B. Gonthier, Frédéric Lamarche, Luc Barret, H. Eysseric

Publikováno v: Alcohol and Alcoholism. 38:550-558

Aims: Ethanol can create progressive neuropathological and functional alterations of neurones. However, the influence of exposure duration is still debated. It is difficult to specify the level of alcohol consumption leading to alcohol-induced brain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14eb551ea81c8537fd3463ef4cff6c2f
https://doi.org/10.1093/alcalc/agg118

Regulation of brain-type creatine kinase by AMP-activated protein kinase: interaction, phosphorylation and ER localization

Autor: Malgorzata Tokarska-Schlattner, Roland D. Tuerk, Luc Barret, Uwe Schlattner, Ramon F. Thali, René A. Brunisholz, Yolanda Auchli, Anna Klaus, Frédéric Lamarche, Dietbert Neumann, Cécile Cottet-Rousselle, Sacnicte Ramirez Rios

Publikováno v: Biochimica et Biophysica Acta-bioenergetics, 1837(8), 1271-1283. Elsevier
Biochimica biophysica acta (BBA)-Bioenergetics
Biochimica biophysica acta (BBA)-Bioenergetics, Elsevier, 2014, 1837 (8), pp.1271-1283. ⟨10.1016/j.bbabio.2014.03.020⟩

International audience; AMP-activated protein kinase (AMPK) and cytosolic brain-type creatine kinase (BCK) cooperate under energy stress to compensate for loss of adenosine triphosphate (ATP) by either stimulating ATP-generating and inhibiting ATP-co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acace03607734790e0b8523c11db36b
https://www.zora.uzh.ch/id/eprint/107587/