Výsledky vyhledávání - "Lucília Kato"

Akademický článek

In vitro antiproliferative and apoptotic effects of thiosemicarbazones based on (-)-camphene and R-(+)-limonene in human melanoma cells.

Autor: Paula Roberta Otaviano Soares, Débora Cristina Souza Passos, Francielly Moreira da Silva, Ana Paula B da Silva-Giardini, Narcimário Pereira Coelho, Cecília Maria Alves de Oliveira, Lucília Kato, Cleuza Conceição da Silva, Lidia Guillo

Publikováno v: PLoS ONE, Vol 18, Iss 11, p e0295012 (2023)

A series of 38 thiosemicarbazone derivatives based on camphene and limonene were evaluated for their antiproliferative activity. Among them, 19 were synthesized and characterized using proton and carbon-13 nuclear magnetic resonance (1H and 13C NMR).

Externí odkaz: https://doaj.org/article/0fb0d8f572c542e094febbfe6bed46d0

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Akademický článek

Efficiency of a new Waiteacircinata extract against rice pathogens

Autor: Jacqueline Campos Borba de Carvalho, Amanda Abdallah Chaibub, Kellen Cristhina Inácio Sousa, Denise Candini de Brito, Marta Cristina Corsi de Filippi, Lucília Kato, Leila Garcês de Araújo

Publikováno v: Pesquisa Agropecuária Tropical, Vol 51, p e66916 (2021)

Waitea circinata (Warcup & Talbot) is an orchid antagonist mycorrhizal fungus with biocontrol potential againstrice pathogens. This study aimed to optimize the extraction method, obtain a new extract and evaluate its efficiency against rice pathogens

Externí odkaz: https://doaj.org/article/575213efa09a40fca2dd1bae2ed138d3

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Akademický článek

Brazilian insulin plant as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antidiabetic compounds in Myrcia rubella Cambess

Autor: Rita de Cássia Lemos Lima, Lucília Kato, Kenneth Thermann Kongstad, Dan Staerk

Publikováno v: Journal of Functional Foods, Vol 45, Iss , Pp 444-451 (2018)

Six species of Myrcia, commonly known as 'insulin plants' in Brazil, were assessed for their potential as functional foods. Thus, dual high-resolution α-glucosidase/PTP1B inhibition profiling and HPLC-HRMS-SPE-NMR analysis were used to identify the

Externí odkaz: https://doaj.org/article/ddf70a16b40f4ab885f2996580d6eef8

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Akademický článek

High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans

Autor: Rita de Cássia Lemos Lima, Kenneth T. Kongstad, Lucília Kato, Marcos José das Silva, Henrik Franzyk, Dan Staerk

Publikováno v: Molecules, Vol 23, Iss 7, p 1755 (2018)

Protein tyrosine phosphatase 1B (PTP1B) is an intracellular enzyme responsible for deactivation of the insulin receptor, and consequently acts as a negative regulator of insulin signal transduction. In recent years, PTP1B has become an important targ

Externí odkaz: https://doaj.org/article/d1970c6ee876438abfcf31d452a0cb52

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Akademický článek

Constituintes químicos das folhas e avaliação da atividade anti-inflamatória de extratos das raízes e folhas de Guettarda pohliana Müll. Arg. (Rubiaceae)

Autor: Gláucio Testa, Paulo Roberto Neves de Oliveira, Cleuza Conceição da Silva, Ivânia Teresinha Albrecht Schuquel, Silvana Maria de Oliveira Santin, Lucília Kato, Cecília Maria Alves de Oliveira, Laura Lícia Milani de Arruda, Ciomar Aparecida Bersani-Amado

Publikováno v: Química Nova, Vol 35, Iss 3, Pp 527-529 (2012)

This phytochemical investigation of Guettarda pohliana leaves led to the isolation of the triterpenes pomolic acid, rotundic acid, 3β,6α,19α,23-tetrahydroxyurs-12-en-28-oic acid, clethric acid, ursolic acid and oleanolic acid, the monoterpenoids l

Externí odkaz: https://doaj.org/article/4b3ac8ec1341462db4657073b8008bea

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Akademický článek

Himatanthus drasticus Leaves: Chemical Characterization and Evaluation of Their Antimicrobial, Antibiofilm, Antiproliferative Activities

Autor: Cristiane Santos Silva e Silva Figueiredo, Joice Castelo Branco Santos, José Artur de Aguiar Castro Junior, Vinícius Galvão Wakui, João F. S. Rodrigues, Mariana Oliveira Arruda, Andrea de Souza Monteiro, Valério Monteiro-Neto, Maria Rosa Quaresma Bomfim, Lucília Kato, Luís Cláudio Nascimento da Silva, Marcos Augusto Grigolin Grisotto

Publikováno v: Molecules, Vol 22, Iss 6, p 910 (2017)

Plant-derived products have played a fundamental role in the development of new therapeutic agents. This study aimed to analyze antimicrobial, antibiofilm, cytotoxicity and antiproliferative potentials of the extract and fractions from leaves of Hima

Externí odkaz: https://doaj.org/article/7dd43c58e11f422684129f82d08359df

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Akademický článek

Inhibition of Paracoccidioides lutzii Pb01 isocitrate lyase by the natural compound argentilactone and its semi-synthetic derivatives.

Autor: Renata Silva do Prado, Ricardo Justino Alves, Cecília Maria Alves de Oliveira, Lucília Kato, Roosevelt Alves da Silva, Guilherme Oliveira Quintino, Silvio do Desterro Cunha, Célia Maria de Almeida Soares, Maristela Pereira

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e94832 (2014)

The dimorphic fungus Paracoccidioides spp. is responsible for paracoccidioidomycosis, the most prevalent systemic mycosis in Latin America, causing serious public health problems. Adequate treatment of mycotic infections is difficult, since fungi are

Externí odkaz: https://doaj.org/article/784d54a9e73a4770aa42258bbbbe518a

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