Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lucía Kordich"'
Publikováno v:
Journal of Thrombosis and Thrombolysis. 35:257-263
Dermatan sulfate (DS) is well-known for its anticoagulant activity through binding to heparin cofactor II (HCII) to enhance thrombin inhibition. It has also been reported that DS has a profibrinolytic effect. We have evaluated the effects of DS solut
Publikováno v:
Blood Coagulation & Fibrinolysis. 17:181-186
To elucidate some of the links between homocysteine and vascular disease, we have evaluated the effect of the amino acid on the formation (by kinetics studies), structure (by electron microscopy) and lysis of the fibrin network, using tissue-type pla
Publikováno v:
Thrombosis Research. 107:75-79
On the basis of growing clinical evidence, it is well known that elevated plasma homocysteine (Hcy) levels are associated with higher risk of venous and arterial thrombosis. Several experimental studies have been carried out in order to elucidate the
Publikováno v:
Journal of thrombosis and thrombolysis. 38(4)
Epidemiologic studies have shown that hyperhomocysteinemia is an independent risk factor for vascular disease. Homocysteine (Hcy) circulates as different species, mostly protein bound, and approximately 1 % as its reduced form and the cyclic thioeste
Publikováno v:
British Journal of Haematology. 114:845-851
Recent studies have shown that patients with antiphospholipid antibodies (aPL) have increased lipid peroxidation. We evaluated the urinary excretion of 11-dehydro thromboxane B2 (11-DH-TXB(2) and isoprostane F(2alpha)III (IPF(2alpha)III), reflecting
Publikováno v:
Thrombosis Research. 100:495-500
Homocysteine (Hcy) increase is now widely accepted as a risk factor for vascular disease. The effects of folic acid (FA) and vitamins B12 and B6 in lowering Hcy have been extensively studied, but there is still little data on the response to FA dieta
Publikováno v:
Thrombosis and Haemostasis. 78:1008-1014
The lupus anticoagulant (LA) and anticardiolipin antibodies (aCL) are clinically relevant because of their association with thrombosis and pregnancy loss. The group of antiphospholipid antibodies (aPL) includes antibodies primarily directed against v
Publikováno v:
Thrombosis and Haemostasis. 75:717-720
SummaryAnticardiolipin antibodies (aCL) detected by standard ELISA are found in association with autoimmune and infectious diseases. It is now recognized that P2 glycoprotein I (β2GPI) is a cofactor for aCL binding to cardiolipin (CL). To examine di
Publikováno v:
Blood Coagulation & Fibrinolysis. 3:765-772
We studied the natural inhibitors (NI) of blood coagulation and fibrinolysis in 50 patients with lupus anticoagulant (LA), in order to identify possible alterations of these NI, that could favour thrombotic manifestations. We found no statistically s
Publikováno v:
Biorheology. 46(5)
Several studies have associated elevated plasma homocysteine (Hcy) levels with higher risk of thrombosis. In order to evaluate possible changes in fibrin strength and deformability mediated by Hcy, the effect of the amino acid on plasma fibrin clot w