Effects of Intravenous Administration of Human Umbilical Cord Blood Stem Cells in 3-Acetylpyridine-Lesioned Rats

Autor: Lucía Calatrava-Ferreras, Rafael Gonzalo-Gobernado, Antonio S. Herranz, Diana Reimers, Teresa Montero Vega, Adriano Jiménez-Escrig, Luis Alberto Richart López, Eulalia Bazán

Publikováno v: Stem Cells International, Vol 2012 (2012)

Cerebellar ataxias include a heterogeneous group of infrequent diseases characterized by lack of motor coordination caused by disturbances in the cerebellum and its associated circuits. Current therapies are based on the use of drugs that correct som

Externí odkaz: https://doaj.org/article/85d2d180b12a475eb7590abdd3867669

Liver Growth Factor Induces Glia-Associated Neuroprotection in an In Vitro Model of Parkinson´s Disease

Autor: Adriano Jimenez-Escrig, María José Casarejos, Gonzalo M. Ulzurrun de Asanza, Rafael Gonzalo-Gobernado, Juan J. Díaz-Gil, Manuela Vallejo-Muñoz, Diana Reimers, Lucía Calatrava Ferreras, Eulalia Bazán

Publikováno v: Brain Sciences
Brain Sciences, Vol 10, Iss 315, p 315 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
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Volume 10
Issue 5

© 2020 by the authors.
Parkinson’s disease is a neurodegenerative disorder characterized by the progressive death of dopaminergic (DA) neurons in the substantia nigra (SN), which leads to a loss of the neurotransmitter dopamine in the basal g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622532bce041074639aec5bddfbe67f8
https://doi.org/10.3390/brainsci10050315

Liver Growth Factor (LGF) Upregulates Frataxin Protein Expression and Reduces Oxidative Stress in Friedreich's Ataxia Transgenic Mice

Autor: Manuela Vallejo-Muñoz, Adriano Jimenez-Escrig, Antonio S. Herranz, Lucía Calatrava-Ferreras, Diana Reimers, Juan P. Velasco-Martín, Eulalia Bazán, Juan J. Díaz-Gil, Rafael Gonzalo-Gobernado, María José Casarejos, Javier Regadera

Publikováno v: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 12; Pages: 2066
International Journal of Molecular Sciences, Vol 17, Iss 12, p 2066 (2016)
Biblos-e Archivo. Repositorio Institucional de la UAM
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Friedreich’s ataxia (FA) is a severe disorder with autosomal recessive inheritance that is caused by the abnormal expansion of GAA repeat in intron 1 of FRDA gen. This alteration leads to a partial silencing of frataxin transcription, causing a mul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e75add55f56116bb959b412451e2e3
https://hdl.handle.net/20.500.12530/24213

Neuroprotective Activity of Peripherally Administered Liver Growth Factor in a Rat Model of Parkinson’s Disease

Autor: Antonio S. Herranz, Adriano Jimenez-Escrig, Juan J. Díaz-Gil, Lucía Calatrava-Ferreras, Rafael Gonzalo-Gobernado, Diana Reimers, Macarena Rodríguez-Serrano, Eulalia Bazán, Cristina Miranda

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e67771 (2013)
PLoS ONE

Liver growth factor (LGF) is a hepatic mitogen purified some years ago that promotes proliferation of different cell types and the regeneration of damaged tissues, including brain tissue. Considering the possibility that LGF could be used as a therap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c4abcdde6a2fc8425c0b66d2748c67
https://doi.org/10.1371/journal.pone.0067771