Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lucía Cócera-Ortega"'
Autor:
Anna M. D. Végh, Arie O. Verkerk, Lucía Cócera Ortega, Jianan Wang, Dirk Geerts, Mischa Klerk, Kirsten Lodder, Ruby Nobel, Anke J. Tijsen, Harsha D. Devalla, Vincent M. Christoffels, Max Medina-Ramírez, Anke M. Smits, Hanno L. Tan, Ronald Wilders, Marie José T. H. Goumans, Gerard J. J. Boink
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Electronic pacemakers still face major shortcomings that are largely intrinsic to their hardware-based design. Radical improvements can potentially be generated by gene or cell therapy-based biological pacemakers. Our previous work identified adenovi
Externí odkaz:
https://doaj.org/article/177579aa19c249d1bc638e48791bd6e1
Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing
Autor:
Anna M. D. Végh, A. Dénise den Haan, Lucía Cócera Ortega, Arie O. Verkerk, Joost P. G. Sluijter, Diane Bakker, Shirley van Amersfoorth, Toon A. B. van Veen, Mischa Klerk, Jurgen Seppen, Jacques M. T. de Bakker, Vincent M. Christoffels, Dirk Geerts, Marie José T. H. Goumans, Hanno L. Tan, Gerard J. J. Boink
Publikováno v:
Molecules, Vol 24, Iss 1, p 181 (2019)
Sustained pacemaker function is a challenge in biological pacemaker engineering. Human cardiomyocyte progenitor cells (CMPCs) have exhibited extended survival in the heart after transplantation. We studied whether lentivirally transduced CMPCs that e
Externí odkaz:
https://doaj.org/article/12417958c72040618ab4b2122a3ff7c4
Autor:
Lucía Cócera-Ortega, Ronald Wilders, Selina C. Kamps, Benedetta Fabrizi, Irit Huber, Ingeborg van der Made, Anouk van den Bout, Dylan K. de Vries, Lior Gepstein, Arie O. Verkerk, Yigal M. Pinto, Anke J. Tijsen
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 4053
International journal of molecular sciences, 23(7):4053. Multidisciplinary Digital Publishing Institute (MDPI)
International journal of molecular sciences, 23(7):4053. Multidisciplinary Digital Publishing Institute (MDPI)
Long-QT syndrome type 1 (LQT1) is caused by mutations in KCNQ1. Patients heterozygous for such a mutation co-assemble both mutant and wild-type KCNQ1-encoded subunits into tetrameric Kv7.1 potassium channels. Here, we investigated whether allele-spec
Autor:
Lior Gepstein, Harsha D. Devalla, Yigal M. Pinto, Yolan J. Reckman, Anke J. Tijsen, Stefan Engelhardt, Simona Aufiero, Ingeborg van der Made, James S. Ware, Anouk van den Bout, Selina C. Kamps, Jiuru Li, Karin Y. van Spaendonck-Zwarts, Lucía Cócera Ortega, Xiaolei Zhang
Publikováno v:
Circulation, 143(15), 1502-1512. Lippincott Williams and Wilkins
Background: TTN (Titin), the largest protein in humans, forms the molecular spring that spans half of the sarcomere to provide passive elasticity to the cardiomyocyte. Mutations that disrupt the TTN transcript are the most frequent cause of hereditar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e1da8f005e0c41117a6dfebfdf546a
http://hdl.handle.net/10044/1/87316
http://hdl.handle.net/10044/1/87316
Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing
Autor:
Arie O. Verkerk, Gerard J.J. Boink, Dirk Geerts, A. Dénise den Haan, Toon A.B. van Veen, Jurgen Seppen, Hanno L. Tan, Diane Bakker, Jacques M.T. de Bakker, Shirley C.M. van Amersfoorth, Joost P.G. Sluijter, Vincent M. Christoffels, Marie-José Goumans, Lucía Cócera Ortega, Mischa Klerk, Anna M. D. Végh
Publikováno v:
Molecules
Volume 24
Issue 1
Molecules, 24(1). MDPI
Molecules, 24(1). John Wiley and Sons Ltd
Molecules, 24(1). Multidisciplinary Digital Publishing Institute
Molecules, Vol 24, Iss 1, p 181 (2019)
Molecules, 24(1):181. Multidisciplinary Digital Publishing Institute
Végh, A M D, den Haan, A D, Cócera Ortega, L, Verkerk, A O, Sluijter, J P G, Bakker, D, van Amersfoorth, S, van Veen, T A B, Klerk, M, Seppen, J, de Bakker, J M T, Christoffels, V M, Geerts, D, Goumans, M J T H, Tan, H L & Boink, G J J 2019, ' Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing ', Molecules, vol. 24, no. 1 . https://doi.org/10.3390/molecules24010181
Volume 24
Issue 1
Molecules, 24(1). MDPI
Molecules, 24(1). John Wiley and Sons Ltd
Molecules, 24(1). Multidisciplinary Digital Publishing Institute
Molecules, Vol 24, Iss 1, p 181 (2019)
Molecules, 24(1):181. Multidisciplinary Digital Publishing Institute
Végh, A M D, den Haan, A D, Cócera Ortega, L, Verkerk, A O, Sluijter, J P G, Bakker, D, van Amersfoorth, S, van Veen, T A B, Klerk, M, Seppen, J, de Bakker, J M T, Christoffels, V M, Geerts, D, Goumans, M J T H, Tan, H L & Boink, G J J 2019, ' Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing ', Molecules, vol. 24, no. 1 . https://doi.org/10.3390/molecules24010181
Sustained pacemaker function is a challenge in biological pacemaker engineering. Human cardiomyocyte progenitor cells (CMPCs) have exhibited extended survival in the heart after transplantation. We studied whether lentivirally transduced CMPCs that e