Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Lucía B. Chemes"'
Autor:
Agostina Giménez, Mariela G. Del Giudice, Paula V. López, Francisco Guaimas, Hugo Sámano-Sánchez, Toby J. Gibson, Lucía B. Chemes, Carlos O. Arregui, Juan E. Ugalde, Cecilia Czibener
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT The modulation of actin polymerization is a common theme among microbial pathogens. Even though microorganisms show a wide repertoire of strategies to subvert the activity of actin, most of them converge in the ones that activate nucleating
Externí odkaz:
https://doaj.org/article/c5673d10faf044ff926512acf31c6281
Autor:
M. Laura Darriba, Celeste Pueblas Castro, Lorena M. Coria, Laura Bruno, M. Laura Cerutti, Lisandro H. Otero, Lucía B. Chemes, Rodolfo M. Rasia, Sebastián Klinke, Juliana Cassataro, Karina A. Pasquevich
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5098-5114 (2022)
U-Omp19 is a bacterial protease inhibitor from Brucella abortus that inhibits gastrointestinal and lysosomal proteases, enhancing the half-life and immunogenicity of co-delivered antigens. U-Omp19 is a novel adjuvant that is in preclinical developmen
Externí odkaz:
https://doaj.org/article/0afb13ee51ac4a0d9e81e38eb40b7819
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1071 (2021)
PDZ domains are binding modules mostly involved in cell signaling and cell–cell junctions. These domains are able to recognize a wide variety of natural targets and, among the PDZ partners, viruses have been discovered to interact with their host v
Externí odkaz:
https://doaj.org/article/be9a83c697c4472aaae15a027f52c625
Publikováno v:
Revista Eureka sobre Enseñanza y Divulgación de las Ciencias, Vol 13, Iss 2, Pp 359-372 (2016)
El objetivo del presente trabajo consistió en desarrollar una propuesta didáctica para la enseñanza con simulaciones (PDES) y analizar las condiciones y momentos didácticos que acompañan su implementación con estudiantes del profesorado en Cien
Externí odkaz:
https://doaj.org/article/9dcbc38bbfb34b04bbb2aaf4df44614a
Autor:
Rita Pancsa, Tamas Lazar, Jesús Alvarado-Valverde, Ramya Kraleti, Hugo Sámano-Sánchez, László Dobson, Melanie Käser, Sushama Michael, Anurag Nagpal, Nazanin Farahi, András Zeke, Mihkel Örd, Bálint Mészáros, Lucía B. Chemes, Manjeet Kumar, Toby J. Gibson, Norman E. Davey
Publikováno v:
Nucleic Acids Research
Almost twenty years after its initial release, the Eukaryotic Linear Motif (ELM) resource remains an invaluable source of information for the study of motif-mediated protein-protein interactions. ELM provides a comprehensive, regularly updated and we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d348302feb51c86fa5073593b09bf23a
https://doi.org/10.1093/nar/gkab975
https://doi.org/10.1093/nar/gkab975
Autor:
Nicolás S. González-Foutel, Juliana Glavina, Wade M. Borcherds, Matías Safranchik, Susana Barrera-Vilarmau, Amin Sagar, Alejandro Estaña, Amelie Barozet, Nicolás A. Garrone, Gregorio Fernandez-Ballester, Clara Blanes-Mira, Ignacio E. Sánchez, Gonzalo de Prat-Gay, Juan Cortés, Pau Bernadó, Rohit V. Pappu, Alex S. Holehouse, Gary W. Daughdrill, Lucía B. Chemes
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nat Struct Mol Biol
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2022, 29 (8), pp.781-790. ⟨10.1038/s41594-022-00811-w⟩
instname
Nat Struct Mol Biol
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2022, 29 (8), pp.781-790. ⟨10.1038/s41594-022-00811-w⟩
Many disordered proteins conserve essential functions in the face of extensive sequence variation, making it challenging to identify the mechanisms responsible for functional selection. Here we identify the molecular mechanism of functional selection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5686ad3777728c8721b6deba4c2af8
https://api.elsevier.com/content/abstract/scopus_id/85135867846
https://api.elsevier.com/content/abstract/scopus_id/85135867846
Autor:
Jesús Alvarado Valverde, Juliana Glavina, Jelena Čalyševa, Dayana Bukirova, Toby J. Gibson, Hugo Sámano-Sánchez, Nicolas Palopoli, Norman E. Davey, Marc Gouw, Manjeet Kumar, Athina Diakogianni, Rita Pancsa, Lucía B. Chemes, Sushama Michael
Publikováno v:
Nucleic Acids Research
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The eukaryotic linear motif (ELM) resource is a repository of manually curated experimentally validated short linear motifs (SLiMs). Since the initial release almost 20 years ago, ELM has become an indispensable resource for the molecular biology com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcaf1973897ef615bf90bf57cd91dfff
http://europepmc.org/articles/PMC7145657
http://europepmc.org/articles/PMC7145657
Autor:
Gary W. Daughdrill, Wade Borcherds, Alex S. Holehouse, Ignacio E. Sánchez, Clara Blanes-Mira, Alejandro Estaña, Susana Barrera-Vilarmau, Amin Sagar, Gregorio Fernández-Ballester, Juan Cortés, Pau Bernadó, Rohit V. Pappu, Amélie Barozet, Juliana Glavina, Gonzalo de Prat-Gay, Lucía B. Chemes, Nicolas S. Gonzalez-Foutel
Many disordered proteins conserve essential functions in the face of extensive sequence variation. This makes it challenging to identify the forces responsible for functional selection. Viruses are robust model systems to investigate functional selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74353c0c8cc7af904aedc731bc0f6b34
https://doi.org/10.1101/2021.05.14.444182
https://doi.org/10.1101/2021.05.14.444182
Autor:
Kiersten M. Ruff, Tamas Lazar, Claudiu C. Gradinaru, María Silvina Fornasari, Silvio C. E. Tosatto, Javier Iserte, Marie Skepö, Julia Marchetti, Sonia Longhi, Teresa Head-Gordon, Toby J. Gibson, Nicolás A. Méndez, Gregory-Neal W. Gomes, Malene Ringkjøbing Jensen, Nicolás A. Garrone, Pau Bernadó, Martin Blackledge, Alexander Miguel Monzon, Dmitri I. Svergun, András Hatos, Julie D. Forman-Kay, Cristina Marino-Buslje, Edward A. Lemke, Eric Fagerberg, Ana Julia Velez Rueda, Sylvain D. Vallet, Elizabeth Martínez-Pérez, Sylvie Ricard-Blum, Tiago N. Cordeiro, Federica Quaglia, Tadeo E. Saldaño, Damiano Piovesan, Peter Tompa, Tanja Mittag, Gustavo Parisi, Mihaly Varadi, Rohit V. Pappu, Lucía B. Chemes, Giovanni Minervini, Edoardo Salladini
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, 49 (D1), pp.D404-D411. ⟨10.1093/nar/gkaa1021⟩
Nucleic acids research, vol 49, iss D1
Nucleic Acids Research, 2021, 49 (D1), pp.D404-D411. ⟨10.1093/nar/gkaa1021⟩
Nucleic Acids Research, Oxford University Press, In press, ⟨10.1093/nar/gkaa1021⟩
Nucleic Acids Research, In press, ⟨10.1093/nar/gkaa1021⟩
Nucleic Acids Research, Oxford University Press, 2021, 49 (D1), pp.D404-D411. ⟨10.1093/nar/gkaa1021⟩
Nucleic acids research, vol 49, iss D1
Nucleic Acids Research, 2021, 49 (D1), pp.D404-D411. ⟨10.1093/nar/gkaa1021⟩
Nucleic Acids Research, Oxford University Press, In press, ⟨10.1093/nar/gkaa1021⟩
Nucleic Acids Research, In press, ⟨10.1093/nar/gkaa1021⟩
The Protein Ensemble Database (PED) (https://proteinensemble.org), which holds structural ensembles of intrinsically disordered proteins (IDPs), has been significantly updated and upgraded since its last release in 2016. The new version, PED 4.0, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62579a66daeda9d1cb3ef52f41885bf
https://hal.univ-grenoble-alpes.fr/hal-03433964/document
https://hal.univ-grenoble-alpes.fr/hal-03433964/document
Publikováno v:
Kjaergaard, M, Glavina, J & Chemes, L B 2021, Predicting the effect of disordered linkers on effective concentrations and avidity with the “C eff calculator” app . in M Merkx (ed.), Linkers in Biomacromolecules . Academic Press, Methods in Enzymology, vol. 647, pp. 145-171 . https://doi.org/10.1016/bs.mie.2020.09.012
Linkers in Biomacromolecules ISBN: 9780128208182
Linkers in Biomacromolecules ISBN: 9780128208182
Linkers are crucial to the functions of multidomain proteins as they couple functional units to encode regulation such as auto-inhibition, enzyme targeting or tuning of interaction strength. A linker changes reactions from bimolecular to unimolecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f0069497b94b0a23921bf613f72b49
https://pure.au.dk/portal/da/publications/predicting-the-effect-of-disordered-linkers-on-effective-concentrations-and-avidity-with-the-ceff-calculator-app(e8d7b908-d0f6-4e64-83ff-4ebbf9bcbd96).html
https://pure.au.dk/portal/da/publications/predicting-the-effect-of-disordered-linkers-on-effective-concentrations-and-avidity-with-the-ceff-calculator-app(e8d7b908-d0f6-4e64-83ff-4ebbf9bcbd96).html