Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Lucía, Piacenza"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Trypanosoma cruzi is the causative agent of Chagas disease which is currently treated by nifurtimox (NFX) and benznidazole (BZ). Nevertheless, the mechanism of action of NFX is not completely established. Herein, we show the protective effects of T.
Externí odkaz:
https://doaj.org/article/17a9eca0ed4a46ecbc643bcdf1ca83fc
Autor:
Carolina Prolo, Damián Estrada, Lucía Piacenza, Diego Benítez, Marcelo A. Comini, Rafael Radi, María Noel Álvarez
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102085- (2021)
Trypanosoma cruzi is a flagellated protozoan that undergoes a complex life cycle between hematophagous insects and mammals. In humans, this parasite causes Chagas disease, which in thirty percent of those infected, would result in serious chronic pat
Externí odkaz:
https://doaj.org/article/5c3f298ec877432bb5e9b75f2d281edd
Autor:
Mayra Fernanda Ricci, Samantha Ribeiro Béla, Michele Macedo Moraes, Maria Terezinha Bahia, Ana Lia Mazzeti, Anny Carolline Silva Oliveira, Luciana Oliveira Andrade, Rafael Radí, Lucía Piacenza, Rosa Maria Esteves Arantes
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
There is a growing consensus that the balance between the persistence of infection and the host immune response is crucial for chronification of Chagas heart disease. Extrapolation for chagasic megacolon is hampered because research in humans and ani
Externí odkaz:
https://doaj.org/article/1a6409a20bce48039dd3b9daa21ebc09
Autor:
Florencia Tomasina, Jennyfer Martínez, Ari Zeida, María Laura Chiribao, Verónica Demicheli, Agustín Correa, Celia Quijano, Laura Castro, Robert H. Carnahan, Paige Vinson, Matt Goff, Tracy Cooper, W. Hayes McDonald, Natalie Castellana, Luciana Hannibal, Paul T. Morse, Junmei Wan, Maik Hüttemann, Ronald Jemmerson, Lucía Piacenza, Rafael Radi
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Cytochrome c (cyt c ) can undergo reversible conformational changes under biologically relevant conditions. Revealing these alternative cyt c conformers at the cell and tissue level is challenging. A monoclonal antibody (mAb) identifying a key confor
Autor:
M. Gabriela Libisch, Paula Faral-Tello, Nisha J. Garg, Rafael Radi, Lucía Piacenza, Carlos Robello
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Chagasic chronic cardiomyopathy is one of the most frequent and severe manifestations of Chagas disease, caused by the parasite Trypanosoma cruzi. The pathogenic and biochemical mechanisms responsible for cardiac lesions remain not completely underst
Externí odkaz:
https://doaj.org/article/dd0fe0dcc2ae4e78b682cf5ca6a8bb5b
Autor:
Patrícia Pereira Dias, Rhayanne Figueiredo Capila, Natália Fernanda do Couto, Damían Estrada, Fernanda Ramos Gadelha, Rafael Radi, Lucía Piacenza, Luciana O Andrade
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 8, p e0005852 (2017)
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, presents a variable clinical course, varying from asymptomatic to serious debilitating pathologies with cardiac, digestive or cardio-digestive impairment. Previous studies using two
Externí odkaz:
https://doaj.org/article/d05dc1e3298945b7ac1c48ac494f92cb
Publikováno v:
Free Radical Biology and Medicine. 192:132-133
Autor:
Samuel L. Freeman, Vera Skafar, Hanna Kwon, Alistair J. Fielding, Peter C.E. Moody, Alejandra Martínez, Federico M. Issoglio, Lucas Inchausti, Pablo Smircich, Ari Zeida, Lucía Piacenza, Rafael Radi, Emma L. Raven
Publikováno v:
The Journal of biological chemistry. 298(8)
The protozoan parasite Trypanosoma cruzi is the causative agent of American trypanosomiasis, otherwise known as Chagas disease. To survive in the host, the T. cruzi parasite needs antioxidant defense systems. One of these is a hybrid heme peroxidase,
Autor:
C. Marin, J.D. Rojas Marquez, Cinthia C. Stempin, Lucía Piacenza, R.E. Baigorrí, Yamile Ana, Rafael Radi, Fabio M. Cerbán, L. Fozzatti, B.A. Maletto
Publikováno v:
Free Radical Biology and Medicine. 163:268-280
Chagas disease caused by Trypanosoma cruzi parasite is an endemic infection in America. It is well known that T. cruzi causes a strong immunosuppression during the acute phase of infection. However, it is not clear whether T. cruzi infection is relat
Autor:
Diego Benítez, Damián Estrada, María Noel Alvarez, Lucía Piacenza, Marcelo A. Comini, Carolina Prolo, Rafael Radi
Publikováno v:
Redox Biology, Vol 46, Iss, Pp 102085-(2021)
Redox Biology
Redox Biology
Trypanosoma cruzi is a flagellated protozoan that undergoes a complex life cycle between hematophagous insects and mammals. In humans, this parasite causes Chagas disease, which in thirty percent of those infected, would result in serious chronic pat