Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Luc, Andries"'
Autor:
Antoni Ribas, Yibing Yan, Lukas Amler, Ilsung Chang, Huibin Yue, Luciana Molinero, Priti S. Hegde, Isabelle Rooney, Ivor Caro, Stephen D. Hurst, Mark Kockx, Luc Andries, Jeffrey Sosman, Paolo A. Ascierto, James Larkin, Brigitte Dréno, Grant A. McArthur, Matthew J. Wongchenko
Supplementary Figure S3. Association of the cell cycle/immune signature with B, lactate dehydrogenase levels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea914eb36a0663bbdbd8e1f2b2f8083
https://doi.org/10.1158/1078-0432.22466237.v1
https://doi.org/10.1158/1078-0432.22466237.v1
Autor:
Patrick Angibaud, Kristof van Emelen, Martin Page, Michel Janicot, Marc Du Jardin, Luc Andries, Ilse Goris, Willem Talloen, Kees Bol, Eugene Cox, Veronique Vreys, Ian Hickson, Ron Gilissen, Laurence Decrane, Bruno Roux, Isabelle Pilatte, Lut Janssen, Ann Belin, Wim Floren, Ann Marin, Peter King, Janine Arts
Purpose: Histone deacetylase (HDAC) inhibitors have shown promising clinical activity in the treatment of hematologic malignancies, but their activity in solid tumor indications has been limited. Most HDAC inhibitors in clinical development only tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2434ea75f5b9b9c5f4fbdf2a8833ab91
https://doi.org/10.1158/1078-0432.c.6517927
https://doi.org/10.1158/1078-0432.c.6517927
Autor:
Antoni Ribas, Yibing Yan, Lukas Amler, Ilsung Chang, Huibin Yue, Luciana Molinero, Priti S. Hegde, Isabelle Rooney, Ivor Caro, Stephen D. Hurst, Mark Kockx, Luc Andries, Jeffrey Sosman, Paolo A. Ascierto, James Larkin, Brigitte Dréno, Grant A. McArthur, Matthew J. Wongchenko
Purpose: The association of tumor gene expression profiles with progression-free survival (PFS) outcomes in patients with BRAFV600-mutated melanoma treated with vemurafenib or cobimetinib combined with vemurafenib was evaluated.Experimental Design: G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ecddf22667cc71d93b7b2572ce9e18d
https://doi.org/10.1158/1078-0432.c.6526268
https://doi.org/10.1158/1078-0432.c.6526268
Autor:
Patrick Angibaud, Kristof van Emelen, Martin Page, Michel Janicot, Marc Du Jardin, Luc Andries, Ilse Goris, Willem Talloen, Kees Bol, Eugene Cox, Veronique Vreys, Ian Hickson, Ron Gilissen, Laurence Decrane, Bruno Roux, Isabelle Pilatte, Lut Janssen, Ann Belin, Wim Floren, Ann Marin, Peter King, Janine Arts
Supplementary Data from JNJ-26481585, a Novel Second-Generation Oral Histone Deacetylase Inhibitor, Shows Broad-Spectrum Preclinical Antitumoral Activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a60eef472554e462da36d628bd346f
https://doi.org/10.1158/1078-0432.22440625.v1
https://doi.org/10.1158/1078-0432.22440625.v1
Autor:
Antoni Ribas, Yibing Yan, Lukas Amler, Ilsung Chang, Huibin Yue, Luciana Molinero, Priti S. Hegde, Isabelle Rooney, Ivor Caro, Stephen D. Hurst, Mark Kockx, Luc Andries, Jeffrey Sosman, Paolo A. Ascierto, James Larkin, Brigitte Dréno, Grant A. McArthur, Matthew J. Wongchenko
Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6bbb305788c7d2546723e62a30a8d0
https://doi.org/10.1158/1078-0432.22466228
https://doi.org/10.1158/1078-0432.22466228
Publikováno v:
MethodsX, Vol 2, Iss C, Pp 272-277 (2015)
Tumor angiogenesis is measured by counting microvessels in tissue sections at high power magnification as a potential prognostic or predictive biomarker. Until now, regions of interest1 1 ROI: region of interest. (ROIs) were selected by manual operat
Externí odkaz:
https://doaj.org/article/1400f62ca2044308a248a0077dabcd0f
Autor:
Nathalie Van Acker, Michael Ragé, Hilde Vermeirsch, Dorien Schrijvers, Rony Nuydens, Geert Byttebier, Maarten Timmers, Stefanie De Schepper, Johannes Streffer, Luc Andries, Léon Plaghki, Patrick Cras, Theo Meert
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161441 (2016)
The in vivo cutaneous nerve regeneration model using capsaicin is applied extensively to study the regenerative mechanisms and therapeutic efficacy of disease modifying molecules for small fiber neuropathy (SFN). Since mismatches between functional a
Externí odkaz:
https://doaj.org/article/9b9286a1bea5424e90b5ec9cadb63903
Autor:
Koen M Marien, Valerie Croons, Yannick Waumans, Ellen Sluydts, Stefanie De Schepper, Luc Andries, Wim Waelput, Erik Fransen, Peter B Vermeulen, Mark M Kockx, Guido R Y De Meyer
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161496 (2016)
Despite all efforts made to develop predictive biomarkers for antiangiogenic therapies, no unambiguous markers have been identified so far. This is due to among others the lack of standardized tests. This study presents an improved microvessel densit
Externí odkaz:
https://doaj.org/article/421154d6011b40f5a40660f694122414
Autor:
Jeffrey A. Sosman, Yibing Yan, Mark M. Kockx, Matthew Wongchenko, Priti S. Hegde, James Larkin, Isabelle Rooney, Antoni Ribas, Stephen D. Hurst, Ivor Caro, Luc Andries, Grant A. McArthur, Lukas C. Amler, Brigitte Dréno, Huibin Yue, Paolo A. Ascierto, Luciana Molinero, Ilsung Chang
Publikováno v:
Clinical Cancer Research. 23:5238-5245
Purpose: The association of tumor gene expression profiles with progression-free survival (PFS) outcomes in patients with BRAFV600-mutated melanoma treated with vemurafenib or cobimetinib combined with vemurafenib was evaluated. Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9999050c7d5f2c4ff3fab487e24e494
https://doi.org/10.1158/1078-0432.ccr-17-0172
https://doi.org/10.1158/1078-0432.ccr-17-0172
Autor:
Elly Verbeek, Hinrich W. H. Göhlmann, Marion Crauwels, Dieder Moechars, Frans W. Verheijen, Rachel Schot, Rudi D'Hooge, Nathalie Van Acker, Stijn Stroobants, An De Bondt, Grazia M.S. Mancini, Luc Andries, Guy Daneels, Michiel W.M. Knaapen, Ilse Goris
Publikováno v:
Experimental Neurology. 291:106-119
Slc17a5(-/-) mice represent an animal model for the infantile form of sialic acid storage disease (SASD). We analyzed genetic and histological time-course expression of myelin and oligodendrocyte (OL) lineage markers in different parts of the CNS, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470d22f55e736a062f60e44e37c917fd