Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Lubomira Tothova"'
Autor:
Chiara Leotta, Leah Hernandez, Lubomira Tothova, Samsul Arefin, Paola Ciceri, Mario Gennaro Cozzolino, Peter Barany, Milan Chromek, Peter Stenvinkel, Karolina Kublickiene
Publikováno v:
Cells, Vol 12, Iss 24, p 2774 (2023)
Circulating cell-free DNA (cfDNA) has diverse applications in oncological, prenatal, toxicological, cardiovascular, and autoimmune diseases, diagnostics, and organ transplantation. In particular, mitochondrial cfDNA (mt-cfDNA) is associated with infl
Externí odkaz:
https://doaj.org/article/20a3fbdb47844376bc77c3a0fb95f58d
Autor:
Norbert Vrbjar, Jana Vlkovicova, Denisa Snurikova, Barbora Kalocayova, Stefan Zorad, Tijana Culafic, Snezana Tepavcevic, Lubomira Tothova, Dominika Radosinska, Marta Kollarova, Jana Radosinska
Publikováno v:
Life, Vol 13, Iss 4, p 931 (2023)
The study aimed to characterize the consequences of a 15-week intake of 10% fructose on the kidney, with the focus on oxidative stress markers and properties of the Na,K-ATPase enzyme. Various antioxidants naturally occurring in common food were demo
Externí odkaz:
https://doaj.org/article/94383f86af3d47dfa70f21e78cb3773a
Autor:
Tomas Jasenovec, Dominika Radosinska, Marta Kollarova, Peter Balis, Stefan Zorad, Norbert Vrbjar, Iveta Bernatova, Sona Cacanyiova, Lubomira Tothova, Jana Radosinska
Publikováno v:
Life, Vol 12, Iss 12, p 2045 (2022)
Oxidative stress and multiple erythrocyte abnormalities have been observed in hypertension. We focused on the effects of angiotensin-converting enzyme 2 (ACE2) inhibition by MLN-4760 inhibitor on angiotensin peptides, oxidative stress parameters, and
Externí odkaz:
https://doaj.org/article/e7c85c1c2b8744cab68ef8bd00ad0d29
Autor:
Allan Bohm, Peter Snopek, Lubomira Tothova, Branislav Bezak, Nikola Jajcay, Marianna Vachalcova, Tomas Uher, Marian Kurecko, Viera Kissova, Katarina Danova, Peter Olejnik, Peter Michalek, Tereza Hlavata, Katarina Petrikova, Viliam Mojto, Jan Kyselovic, Stefan Farsky
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Atrial fibrillation (AF) is associated with high risk of stroke preventable by timely initiation of anticoagulation. Currently available screening tools based on ECG are not optimal due to inconvenience and high costs. Aim of this study w
Externí odkaz:
https://doaj.org/article/647a6d3d5da9442581dc6553c879d07b
Autor:
Norbert Vrbjar, Tomas Jasenovec, Marta Kollarova, Denisa Snurikova, Maria Chomova, Dominika Radosinska, Ivana Shawkatova, Lubomira Tothova, Jana Radosinska
Publikováno v:
Biology, Vol 11, Iss 10, p 1519 (2022)
For a better insight into relations between type 2 diabetes mellitus (T2DM) and Na,K-ATPase properties in kidneys, we aimed to characterize two subgroups of ZDF obese (fa/fa) rats, with more and less developed T2DM, and compare them with two controls
Externí odkaz:
https://doaj.org/article/2b3139b4395f403c9bacf29e2852fe7c
Autor:
Tomas Jasenovec, Dominika Radosinska, Marta Kollarova, Norbert Vrbjar, Peter Balis, Simona Trubacova, Ludovit Paulis, Lubomira Tothova, Ivana Shawkatova, Jana Radosinska
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1227 (2022)
The objective of our study was to contribute to the characterization of monocrotaline-induced pulmonary arterial hypertension (PAH) in a rat model, with emphasis on the renin–angiotensin–aldosterone system, parameters of oxidative stress, the act
Externí odkaz:
https://doaj.org/article/385c659c07d54d5b9e634e136e2695ae
Autor:
Zuzana Vrablicova, Kristina Tomova, Lubomira Tothova, Janka Babickova, Barbora Gromova, Barbora Konecna, Robert Liptak, Tibor Hlavaty, Roman Gardlik
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Background: The role of cell-free DNA (cfDNA) in the pathogenesis of inflammatory bowel disease (IBD) has been recently suggested. The aim of this study was to analyze circulating cfDNA and deoxyribonuclease (DNase) activity in IBD patients in clinic
Externí odkaz:
https://doaj.org/article/1437b095985a4b3e94ca0a1f26a11fe7
Autor:
Tomas Jasenovec, Dominika Radosinska, Marta Kollarova, Peter Balis, Kristina Ferenczyova, Barbora Kalocayova, Monika Bartekova, Lubomira Tothova, Jana Radosinska
Publikováno v:
Molecules, Vol 26, Iss 16, p 4868 (2021)
Diabetes mellitus is characterized by tissue oxidative damage and impaired microcirculation, as well as worsened erythrocyte properties. Measurements of erythrocyte deformability together with determination of nitric oxide (NO) production and osmotic
Externí odkaz:
https://doaj.org/article/a3da20acd9fa47ccab805749fcb08597
Autor:
Marta Kollarova, Angelika Puzserova, Peter Balis, Dominika Radosinska, Lubomira Tothova, Monika Bartekova, Miroslav Barancik, Jana Radosinska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7286 (2020)
Matrix metalloproteinases (MMPs) are important in the pathogenesis of numerous diseases. The present study aimed to monitor the activation of MMP-2 and MMP-9 in spontaneously hypertensive rats (SHR) and their normotensive counterparts—Wistar-Kyoto
Externí odkaz:
https://doaj.org/article/959bb4f5c1b44dffbd0493537e86cc1f
Autor:
Kristina Ferenczyova, Barbora Kalocayova, Lucia Kindernay, Marek Jelemensky, Peter Balis, Andrea Berenyiova, Anna Zemancikova, Veronika Farkasova, Matus Sykora, Lubomira Tothova, Tomas Jasenovec, Jana Radosinska, Jozef Torok, Sona Cacanyiova, Miroslav Barancik, Monika Bartekova
Publikováno v:
Molecules, Vol 25, Iss 1, p 187 (2020)
Background: Quercetin (QCT) was shown to exert beneficial cardiovascular effects in young healthy animals. The aim of the present study was to determine cardiovascular benefits of QCT in older, 6-month and 1-year-old Zucker diabetic fatty (ZDF) rats
Externí odkaz:
https://doaj.org/article/51026863fc894b47b8624c6e4b3b867d