Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Lubomir T. Lubomirov"'
Autor:
Monique Jänsch, Lubomir T. Lubomirov, Maximilian Trum, Tatjana Williams, Joachim Schmitt, Kai Schuh, Fatimunnisa Qadri, Lars S. Maier, Michael Bader, Oliver Ritter
Publikováno v:
FEBS Open Bio, Vol 13, Iss 1, Pp 118-132 (2023)
Recent evidence demonstrated that alterations in the QT interval duration on the ECG are not only determined by mutations in genes for ion channels, but also by modulators of ion channels. Changes in the QT interval duration beyond certain thresholds
Externí odkaz:
https://doaj.org/article/8069512204c84c57aff6a458cf969748
Autor:
Kangbo Li, Mengjun Dai, Mesud Sacirovic, Claudia Zemmrich, Nikolaos Pagonas, Oliver Ritter, Olaf Grisk, Lubomir T. Lubomirov, Martin A. Lauxmann, Peter Bramlage, Anja Bondke Persson, Eva Buschmann, Ivo Buschmann, Philipp Hillmeister
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundWe investigated the association between leukocyte telomere length, mitochondrial DNA copy number, and endothelial function in patients with aging-related cardiovascular disease (CVD).MethodsIn total 430 patients with CVD and healthy persons
Externí odkaz:
https://doaj.org/article/57b416c4162546d4acccefcd32cda3be
Autor:
Lubomir T. Lubomirov, Mechthild M. Schroeter, Veronika Hasse, Marina Frohn, Doris Metzler, Maria Bust, Galyna Pryymachuk, Jürgen Hescheler, Olaf Grisk, Joseph M. Chalovich, Neil R. Smyth, Gabriele Pfitzer, Symeon Papadopoulos
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Stretch-induced vascular tone is an important element of autoregulatory adaptation of cerebral vasculature to maintain cerebral flow constant despite changes in perfusion pressure. Little is known as to the regulation of tone in senescent basilar art
Externí odkaz:
https://doaj.org/article/19a2ea5031624db0a6613a250fb065b3
Autor:
Kangbo Li, Victoria Kratzmann, Mengjun Dai, Nora Gatzke, Petra Rocic, Peter Bramlage, Olaf Grisk, Lubomir T. Lubomirov, Meike Hoffmeister, Martin A. Lauxmann, Oliver Ritter, Eva Buschmann, Michael Bader, Anja Bondke Persson, Ivo Buschmann, Philipp Hillmeister
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
BackgroundWe investigated the pleiotropic effects of an angiotensin receptor-neprilysin inhibitor (ARNi) on collateral-dependent myocardial perfusion in a rat model of coronary arteriogenesis, and performed comprehensive analyses to uncover the under
Externí odkaz:
https://doaj.org/article/13db640770fa420caa670d11ac4a6c05
Autor:
Lubomir T. Lubomirov, René Mantke, Thomas Enzmann, Doris Metzler, Tatiana Korotkova, Jürgen Hescheler, Gabriele Pfitzer, Olaf Grisk
Publikováno v:
Journal of Hypertension.
Autor:
Doris Metzler, Lubomir T. Lubomirov, Gabriele Pfitzer, Oliver Ritter, Monique Jänsch, Olaf Grisk, Mechthild M. Schroeter, Maria Bust, Symeon Papadopoulos, Jürgen Hescheler
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 130:70-83
This work explored the mechanism of augmented stress-induced vascular reactivity of senescent murine femoral arteries (FAs). Mechanical and pharmacological reactivity of young (12-25 weeks, y-FA) and senescent (>104 weeks, s-FAs) femoral arteries was
Autor:
Gabriele Pfitzer, Jörg Dötsch, Felix Lechner, Eva Nüsken, Jenny Voggel, Maria Wohlfarth, Miguel A. Alejandre Alcazar, Gregor Fink, Kai D. Nüsken, Martin Hellmich, Kija Shah-Hosseini, Lubomir T. Lubomirov
Publikováno v:
American Journal of Physiology-Renal Physiology. 321:F93-F105
For the first time, our study presents wire myography data from renal interlobar arteries (RIAs) and mesenteric arteries of young adult rat offspring after intrauterine growth restriction (IUGR). Our data indicate that myogenic tone in RIAs is dysfun
Autor:
Monique Jänsch, Lubomir T. Lubomirov, Maximilian Trum, Tatjana Williams, Joachim Schmitt, Kai Schuh, Fatimunnisa Qadri, Lars S. Maier, Michael Bader, Oliver Ritter
Publikováno v:
FEBS open bioReferences.
Recent evidence demonstrated that alterations in the QT interval duration on the ECG are not only determined by mutations in genes for ion channels, but also by modulators of ion channels. Changes in the QT interval duration beyond certain thresholds
Publikováno v:
General physiology and biophysics. 39:157-168
Cerebral blood supply is finely tuned by regulatory mechanisms depending on vessel caliber the disruption of which contributes to the development of diseases such as vascular dementia, Alzheimer's and Parkinson 's diseases. This study scopes whether
Autor:
Gabriele Pfitzer, Margarethe Wiedenmann, Jiehua Qiu, Kai Michael Schubert, Stephanie Blodow, Ulrich Pohl, Lubomir T. Lubomirov, Holger Schneider
Publikováno v:
Circulation Research. 121:149-161
Rationale: Decreasing Ca 2+ sensitivity of vascular smooth muscle (VSM) allows for vasodilation without lowering of cytosolic Ca 2+ . This may be particularly important in states requiring maintained dilation, such as hypoxia. AMP-related kinase (AMP