Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lubna Swellmeen"'
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 2, p 57 (2023)
Clarithromycin (CLR), categorized as a Biopharmaceutical Classification System class II drug, has several gastrointestinal tract side effects and an extremely unpalatable bitter taste. The current study aimed to design transdermal patch-embedded CLR
Externí odkaz:
https://doaj.org/article/039139b77ea541f6b7556bc51d13cdff
Autor:
Ahlam Zaid Alkilani, Rania Hamed, Hajer Abdo, Lubna Swellmeen, Haneen A. Basheer, Walaa Wahdan, Amani D. Abu Kwiak
Publikováno v:
ACS Omega. 7:39782-39793
Several novel, innovative approaches for improving transdermal delivery of BCS class III drugs have been proposed. Despite their great aqueous solubility, BCS class III drugs have the drawback of limited permeability. The objective of the current wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77283320a91abda5d690604b41bac63
https://doi.org/10.1021/acsomega.2c03762
https://doi.org/10.1021/acsomega.2c03762
Autor:
Lubna Swellmeen, Amal H Uzrail
Publikováno v:
Tropical Journal of Pharmaceutical Research. 19:1329-1337
Leptin, a cytokine-like hormone produced by adipocytes, modulates innate and adaptive responses of the immune system. Several reports have indicated that leptin exerts pro-inflammatory effects which significantly trigger autoimmune responses in chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::590a0ac7240c2280052e88b6e504adde
https://doi.org/10.4314/tjpr.v19i6.30
https://doi.org/10.4314/tjpr.v19i6.30
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol. 20 No. 3 (2021); 599-604
Purpose: To synthesize quinoxaline derivatives and investigate their inhibitory effects on glycogen synthase kinase (GSK)-3β in vitro. Methods: Quinoxaline derivatives were synthesized via reaction between synthon 1 and DL- 2-amino succinic acid, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233e9674a42f7057a28b70b7cd3778ee
https://www.ajol.info/index.php/tjpr/article/view/220166
https://www.ajol.info/index.php/tjpr/article/view/220166
Publikováno v:
Oriental Journal Of Chemistry. 35:1248-1253
Fluoroquinolones are well known to have an anti-infective action. In the present study we described the synthesis of novel florouquinolones derivative as antimicrobial agent. The biological test highlighted a good inhibitory activity for the 7-Chloro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767f5e4fc2b3f9fc83fe880873068c92
https://doi.org/10.13005/ojc/350401
https://doi.org/10.13005/ojc/350401
Autor:
Lubna Swellmeen, Rand Shahin, Yaser Al-Qarar’h, Tahani Alwidyan, Iman Mansi, Nabil N. Al-Hashimi, O. H. Shaheen
Publikováno v:
Journal of molecular graphicsmodelling. 80
Targeting tropomycin kinase A (TrkA) by small molecule inhibitors is considered as a promising strategy for treating several human cancers. To achieve this goal, a ligand based QSAR model was applied using the Discovery studio 4.5 (DS 4.5). Hence, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31c6a1531d01c92b13ce70bb6d558f9
https://pubmed.ncbi.nlm.nih.gov/29454290
https://pubmed.ncbi.nlm.nih.gov/29454290
Publikováno v:
Bioorganicmedicinal chemistry. 25(17)
Over expression of Human phosphatidyl inositol mannoside kinases isoform 1 (Pim-1 kinase) has been reported in several leukemia and solid tumors. Our continuous interest to reveal the secrecies of the mysterious Pim-1 kinase binding pocket has led us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65597e1b9c02385e80959832bd460bb
https://pubmed.ncbi.nlm.nih.gov/28760531
https://pubmed.ncbi.nlm.nih.gov/28760531
Publikováno v:
Journal of computer-aided molecular design. 30(1)
Targeting Proviral integration-site of murine Moloney leukemia virus 1 kinase, hereafter called Pim-1 kinase, is a promising strategy for treating different kinds of human cancer. Headed for this a total list of 328 formerly reported Pim-1 kinase inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd3b089b5fcef1d3cf98a61d596313b
https://pubmed.ncbi.nlm.nih.gov/26685860
https://pubmed.ncbi.nlm.nih.gov/26685860