Biophysical Characterization of a Novel Phosphopentomutase from the Hyperthermophilic Archaeon Thermococcus kodakarensis .

Autor: Naz Z; School of Biological Sciences, University of the Punjab, Lahore 54590, Pakistan.; Center for Structural Biology, National Cancer Institute, National Institutes of Health, Frederic, MD 21702, USA., Lubkowski J; Center for Structural Biology, National Cancer Institute, National Institutes of Health, Frederic, MD 21702, USA., Saleem M; School of Biological Sciences, University of the Punjab, Lahore 54590, Pakistan., Aslam M; School of Biological Sciences, University of the Punjab, Lahore 54590, Pakistan., Rahman M; School of Biological Sciences, University of the Punjab, Lahore 54590, Pakistan., Wlodawer A; Center for Structural Biology, National Cancer Institute, National Institutes of Health, Frederic, MD 21702, USA., Rashid N; School of Biological Sciences, University of the Punjab, Lahore 54590, Pakistan.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 30; Vol. 25 (23). Date of Electronic Publication: 2024 Nov 30.

RrA, an enzyme from Rhodospirillum rubrum, is a prototype of a new family of short-chain L-asparaginases.

Autor: Zhang D; Center for Structural Biology, National Cancer Institute, Frederick, Maryland, USA., Czapinska H; Laboratory of Structural Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland.; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., Bochtler M; Laboratory of Structural Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland.; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., Wlodawer A; Center for Structural Biology, National Cancer Institute, Frederick, Maryland, USA., Lubkowski J; Center for Structural Biology, National Cancer Institute, Frederick, Maryland, USA.

Publikováno v: Protein science : a publication of the Protein Society [Protein Sci] 2024 Apr; Vol. 33 (4), pp. e4920.

Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation.

Autor: Lemma B; Center for Biomolecular Structure and Organization, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, 20742, USA., Zhang D; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA., Vamisetti GB; Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Haifa, 3200008, Israel., Wentz BG; Center for Biomolecular Structure and Organization, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, 20742, USA., Suga H; Department of Chemistry, Graduate School of Science, The University of Tokyo, Bunkyo-ku, 7-3-1 Hongo, Bunkyo, Tokyo, 113-0033, Japan., Brik A; Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Haifa, 3200008, Israel. abrik@technion.ac.il., Lubkowski J; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA. jacek.lubkowski2@nih.gov., Fushman D; Center for Biomolecular Structure and Organization, Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, 20742, USA. fushman@umd.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Nov 08; Vol. 14 (1), pp. 7212. Date of Electronic Publication: 2023 Nov 08.

Structural and biochemical properties of L-asparaginase.

Autor: Lubkowski J; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Wlodawer A; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.

Publikováno v: The FEBS journal [FEBS J] 2021 Jul; Vol. 288 (14), pp. 4183-4209. Date of Electronic Publication: 2021 Jun 19.

The dimeric form of bacterial l-asparaginase YpAI is fully active.

Autor: Strzelczyk P; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Zhang D; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Alexandratos J; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Piszczek G; Biophysics Core Facility, National Heart, Lung, and Blood Institute, Bethesda, MD, USA., Wlodawer A; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Lubkowski J; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.

Publikováno v: The FEBS journal [FEBS J] 2023 Feb; Vol. 290 (3), pp. 780-795. Date of Electronic Publication: 2022 Oct 06.