Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Lubka T, Roumenina"'
Autor:
Margot Revel, Mikel Rezola Artero, Houcine Hamidi, Anne Grunenwald, Loris Blasco, Yann A. Vano, Stephane Marie Oudard, Rafael Sanchez-Salas, Petr Macek, Lara Rodriguez Sanchez, Xavier Cathelineau, Benoit Vedié, Catherine Sautes-Fridman, Wolf Herman Fridman, Lubka T. Roumenina, Marie-Agnes Dragon-Durey
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Despite the progress of anti-cancer treatment, the prognosis of many patients with solid tumors is still dismal. Reliable noninvasive biomarkers are needed to predict patient survival and therapy response. Here, we propose a Humoral Complementomics a
Externí odkaz:
https://doaj.org/article/e77890b3400c4f229ab62a5c056568ed
Autor:
Cyril Planchais, Remi Noe, Marie Gilbert, Maxime Lecerf, Srini V. Kaveri, Sébastien Lacroix-Desmazes, Lubka T. Roumenina, Jordan D. Dimitrov
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Oxidized hemoglobin induces polyreactivity and autoreactivity of human IgG through direct transfer and binding of heme to the variable region of IgG, which contributes to a better understanding of the physiopathology of hemolytic diseases.
Externí odkaz:
https://doaj.org/article/f7705e6c7787475685bc115f0bcea333
Autor:
Rafael Cardoso Maciel Costa Silva, Luis Batista Tan, Andreza Moreira dos Santos Gama, Nuccia Nicole Theodoro De Cicco, Nicolas S. Merle, Lubka T. Roumenina, Yi Zhang, Gregory C. Henderson, André N.A. Gonçalves, Georgia C. Atella, João Trindade Marques, Leonardo Holanda Travassos, Claudia N. Paiva, Bénédicte Manoury, Marcelo Torres Bozza
Publikováno v:
Advances in Redox Research, Vol 8, Iss , Pp 100069- (2023)
Free heme released from hemoglobin contributes to exacerbated inflammation and tissue damage in hemolytic diseases. While a moderate level of free heme does not cause intravascular inflammation by itself, its presence during infection greatly enhance
Externí odkaz:
https://doaj.org/article/caf0e5f9c6324117a28d75b119f708d1
Autor:
Alexandra Gerogianni, Jordan D. Dimitrov, Alessandra Zarantonello, Victoria Poillerat, Satheesh Chonat, Kerstin Sandholm, Karin E. McAdam, Kristina N. Ekdahl, Tom E. Mollnes, Camilla Mohlin, Lubka T. Roumenina, Per H. Nilsson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hemolysis, as a result of disease or exposure to biomaterials, is characterized by excess amounts of cell-free heme intravascularly and consumption of the protective heme-scavenger proteins in plasma. The liberation of heme has been linked to the act
Externí odkaz:
https://doaj.org/article/0a05f1bf9b5b4cc29cb6730c4a4c8d47
Autor:
Marie-Sophie Meuleman, Anna Duval, Véronique Fremeaux-Bacchi, Lubka T. Roumenina, Sophie Chauvet
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As part of the innate immune system, the complement system plays a key role in defense against pathogens and in host cell homeostasis. This enzymatic cascade is rapidly triggered in the presence of activating surfaces. Physiologically, it is tightly
Externí odkaz:
https://doaj.org/article/304522c81a1f41fa83def17234263253
Autor:
Florent Petitprez, Sacha Levy, Cheng-Ming Sun, Maxime Meylan, Christophe Linhard, Etienne Becht, Nabila Elarouci, David Tavel, Lubka T. Roumenina, Mira Ayadi, Catherine Sautès-Fridman, Wolf H. Fridman, Aurélien de Reyniès
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-15 (2020)
Abstract Quantifying tissue-infiltrating immune and stromal cells provides clinically relevant information for various diseases. While numerous methods can quantify immune or stromal cells in human tissue samples from transcriptomic data, few are ava
Externí odkaz:
https://doaj.org/article/0723850808e44fef8035c80ac43ffd5c
Autor:
Sigridur Sunna Aradottir, Ann-Charlotte Kristoffersson, Lubka T. Roumenina, Anna Bjerre, Pavlos Kashioulis, Runolfur Palsson, Diana Karpman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Complement factor B (FB) mutant variants are associated with excessive complement activation in kidney diseases such as atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy and membranoproliferative glomerulonephritis (MPGN). Patients with aH
Externí odkaz:
https://doaj.org/article/beb06f98da314f579d680de0c2454741
Autor:
Idris Boudhabhay, Marion Rabant, Lubka T. Roumenina, Louis-Marie Coupry, Victoria Poillerat, Armance Marchal, Véronique Frémeaux-Bacchi, Khalil El Karoui, Mehran Monchi, Franck Pourcine
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundThe coronavirus disease 2019 (COVID-19) pandemic has affected millions of people worldwide. A clinical series of Kawasaki-like multisystem inflammatory syndrome (MIS), occurring after SARS-CoV-2 infection, have been described in children (M
Externí odkaz:
https://doaj.org/article/44395abd031148dcbd3d69b436755546
Autor:
Irati Garmendia, Aditi Varthaman, Solenne Marmier, Mahmud Angrini, Ingrid Matchoua, Aurelie Darbois-Delahousse, Nathalie Josseaume, Pierre-Emmanuel Foy, Lubka T. Roumenina, Naïra Naouar, Maxime Meylan, Sophie Sibéril, Jules Russick, Pierre-Emmanuel Joubert, Karen Leroy, Diane Damotte, Audrey Mansuet-Lupo, Marie Wislez, Marco Alifano, Laurie Menger, Ignacio Garcia-Verdugo, Jean-Michel Sallenave, Olivier Lantz, Florent Petitprez, Isabelle Cremer
Publikováno v:
Cancer Immunology Research. 11:530-545
One billion people worldwide get flu every year, including patients with non–small cell lung cancer (NSCLC). However, the impact of acute influenza A virus (IAV) infection on the composition of the tumor microenvironment (TME) and the clinical outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::564fd9e809b1b2d9fd3b03e07dd096ea
https://doi.org/10.1158/2326-6066.cir-22-0534
https://doi.org/10.1158/2326-6066.cir-22-0534
Autor:
Nicolas S. Merle, Juliette Leon, Victoria Poillerat, Anne Grunenwald, Idris Boudhabhay, Samantha Knockaert, Tania Robe-Rybkine, Carine Torset, Matthew C. Pickering, Sophie Chauvet, Veronique Fremeaux-Bacchi, Lubka T. Roumenina
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Intravascular hemolysis of any cause can induce acute kidney injury (AKI). Hemolysis-derived product heme activates the innate immune complement system and contributes to renal damage. Therefore, we explored the role of the master complement regulato
Externí odkaz:
https://doaj.org/article/46b034fe48a84de9a00b0c1dc8408830