Utilization of Liquid Chromatography-Mass Spectrometry and High-Resolution Ion Mobility-Mass Spectrometry to Characterize Therapeutically Relevant Peptides with Asparagine Deamidation and Isoaspartate.

Autor: Dykstra AB; Pre-Pivotal Attribute Sciences, Amgen, Inc, Thousand Oaks, California 91320, United States., Lubinsky TG; MOBILion Systems, Chadds Ford, Pennsylvania 19317, United States., Vitrac H; MOBILion Systems, Chadds Ford, Pennsylvania 19317, United States., Campuzano IDG; Molecular Analytics, Amgen, Inc, Thousand Oaks, California 91320, United States., Bondarenko PV; Pre-Pivotal Attribute Sciences, Amgen, Inc, Thousand Oaks, California 91320, United States., Simone AR; MOBILion Systems, Chadds Ford, Pennsylvania 19317, United States.

Publikováno v: Analytical chemistry [Anal Chem] 2024 Dec 23. Date of Electronic Publication: 2024 Dec 23.