Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Lubica Horakova"'
Autor:
Jana Viskupicova, Dusan Blaskovic, Sabina Galiniak, Mirosław Soszyński, Grzegorz Bartosz, Lubica Horakova, Izabela Sadowska-Bartosz
Publikováno v:
Redox Biology, Vol 5, Iss , Pp 381-387 (2015)
Exposure to high glucose concentrations in vitro is often employed as a model for understanding erythrocyte modifications in diabetes. However, effects of such experiments may be affected by glucose consumption during prolonged incubation and changes
Externí odkaz:
https://doaj.org/article/e018587543e64bbdb355446a0620c853
Autor:
Vladimir Heger, Zoofishan Zoofishan, Jana Viskupicova, Lubica Horakova, Magdalena Majekova, Attila Hunyadi, Barbora Benesova
Publikováno v:
ACS Medicinal Chemistry Letters. 11:1006-1013
The ability of phenolic compounds from Morus nigra to modulate sarco-endoplasmic Ca2+-ATPase (SERCA1) activity was analyzed. Enzyme activity decrease correlated with the binding energy of agents to SERCA1. Results from theoretical and experimental ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2ec7a5472e5eabe783e3a325a525ac3
https://doi.org/10.1021/acsmedchemlett.0c00047
https://doi.org/10.1021/acsmedchemlett.0c00047
Autor:
Vladimir Heger, Minna Rahnasto-Rilla, Jonna Tyni, Lubica Horakova, Attila Hunyadi, Maija Lahtela-Kakkonen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 111, Iss, Pp 1326-1333 (2019)
Polyphenols synthesized by plants and fungi have various pharmacological effects. The ability of polyphenols to modulate sirtuins has gained considerable interest due to the role of sirtuins in aging, insulin sensitivity, lipid metabolism, inflammati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd70843b649f52c02f8fc049ccaf2760
http://www.sciencedirect.com/science/article/pii/S0753332218374146
http://www.sciencedirect.com/science/article/pii/S0753332218374146
Autor:
Vladimir, Heger, Barbora, Benesova, Jana, Viskupicova, Magdalena, Majekova, Zoofishan, Zoofishan, Attila, Hunyadi, Lubica, Horakova
Publikováno v:
ACS Med Chem Lett
[Image: see text] The ability of phenolic compounds from Morus nigra to modulate sarco-endoplasmic Ca(2+)-ATPase (SERCA1) activity was analyzed. Enzyme activity decrease correlated with the binding energy of agents to SERCA1. Results from theoretical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff949e84edaacb3cb10ff130b65b8ee9
https://pubmed.ncbi.nlm.nih.gov/32435418
https://pubmed.ncbi.nlm.nih.gov/32435418
Autor:
Vladimir Heger, Lucia Račková, Petronela Zizkova, Magdalena Majekova, Jana Viskupicova, Lubica Horakova
Publikováno v:
Cell Calcium. 74:112-122
A novel pathway of methylglyoxal (MGX)-induced apoptosis via sarcoplasmic reticulum Ca2+-ATPase (SERCA) is presented. Interaction of SERCA1 with MGX was investigated by molecular docking and experimentally in a cell-free system. MGX concentration- an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d392e5154b35842e3005d4be1252335
https://doi.org/10.1016/j.ceca.2018.06.003
https://doi.org/10.1016/j.ceca.2018.06.003
Publikováno v:
Phytotherapy Research. 31:1702-1707
Natural standardized flavonoid extract from the bark of Pinus pinaster, Pycnogenol (Pyc), was recently found to decrease intensively the activity of sarcoplasmic reticulum Ca2+ -ATPase of rabbit skeletal muscle (SERCA1). On the basis of this inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71c5b5f6e2c3bf31e3cdcf9035394e5a
https://doi.org/10.1002/ptr.5894
https://doi.org/10.1002/ptr.5894
Publikováno v:
Chemico-Biological Interactions. 265:36-46
A set of O-substituted quercetin derivatives was prepared with the aim to optimize bioavailability and redox properties of quercetin, a known agent with multiple health beneficial effects. Electron-acceptor/-donor properties of the agents were evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbb1e0d6d65ac30d32e22b857aa4ca2
https://doi.org/10.1016/j.cbi.2017.01.019
https://doi.org/10.1016/j.cbi.2017.01.019
Autor:
Ima Dovinova, Miroslava Majzunova, Miroslava Kvandova, Linda Gresova, Angelika Puzserova, Miroslav Barancik, Lubica Horakova, Peter Balis
Publikováno v:
Free Radical Biology and Medicine. 159:S89-S90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6167fb8b249e8bdac60b342800023ece
https://doi.org/10.1016/j.freeradbiomed.2020.10.231
https://doi.org/10.1016/j.freeradbiomed.2020.10.231
Autor:
Betul Karademir, Michael J. Davies, Chantal Houée-Levin, Christian Schöneich, Corinne M. Spickett, Lubica Horakova, Krzysztof Bobrowski
Publikováno v:
Free Radical Research. 49:347-373
Protein oxidation is increasingly recognised as an important modulator of biochemical pathways controlling both physiological and pathological processes. While much attention has focused on cysteine modifications in reversible redox signalling, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a999de5725b49f023a2ce6c5c7bc1fba
https://doi.org/10.3109/10715762.2015.1007968
https://doi.org/10.3109/10715762.2015.1007968
Publikováno v:
Molecular and Cellular Biochemistry. 402:51-62
In this study we analyzed the protective action of the flavonoid rutin on peroxynitrite (ONOO(-)) mediated impairment of sarcoplasmic reticulum Ca(2+)-ATPase (SERCA1 isoform), especially related to posttranslational and conformational changes. Rutin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5883911e33b36cfde75a01adb8f29aa
https://doi.org/10.1007/s11010-014-2313-y
https://doi.org/10.1007/s11010-014-2313-y