Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Luba Eli-Berchoer"'
Autor:
Yasmin Jaber, Yasmine Netanely, Reem Naamneh, Or Saar, Khaled Zubeidat, Yasmin Saba, Olga Georgiev, Paz Kles, Or Barel, Yael Horev, Omri Yosef, Luba Eli-Berchoer, Chen Nadler, Gili Betser-Cohen, Hagit Shapiro, Eran Elinav, Asaf Wilensky, Avi-Hai Hovav
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The postnatal interaction between microbiota and the immune system establishes lifelong homeostasis at mucosal epithelial barriers, however, the barrier-specific physiological activities that drive the equilibrium are hardly known. During we
Externí odkaz:
https://doaj.org/article/ac25d743859648f581eb8c7e71667088
Autor:
Karthikeyan Pandi, Sarah Angabo, Jeba Gnanasekaran, Hasnaa Makkawi, Luba Eli-Berchoer, Fabian Glaser, Gabriel Nussbaum
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011284 (2023)
Porphyromonas gingivalis is a Gram-negative anaerobic bacterium that thrives in the inflamed environment of the gingival crevice, and is strongly associated with periodontal disease. The host response to P. gingivalis requires TLR2, however P. gingiv
Externí odkaz:
https://doaj.org/article/111b13a5f8454f9881737d0868d4ab00
Autor:
Khaled Zubeidat, Yasmin Jaber, Yasmin Saba, Or Barel, Reem Naamneh, Yasmin Netanely, Yael Horev, Luba Eli-berchoer, Amjad Shhadeh, Omri Yosef, Eliran Arbib, Gili Betser-Cohen, Chen Nadler, Hagit Shapiro, Eran Elinav, Doron J. Aframian, Asaf Wilensky, Avi-Hai Hovav
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111981- (2023)
Summary: While saliva regulates the interplay between the microbiota and the oral immune system, the mechanisms establishing postnatal salivary immunity are ill-defined. Here, we show that high levels of neutrophils and neonatal Fc receptor (FcRn)-tr
Externí odkaz:
https://doaj.org/article/1c1d66e6c46f4ceab37daa231b8662cc
Autor:
Gabriel Mizraji, Maria Nassar, Hadas Segev, Hafiz Sharawi, Luba Eli-Berchoer, Tal Capucha, Tsipora Nir, Yaara Tabib, Avraham Maimon, Shira Dishon, Lior Shapira, Gabriel Nussbaum, Asaf Wilensky, Avi-Hai Hovav
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 419-431 (2017)
Summary: Whereas type I interferons (IFNs-I) were proposed to be elevated in human periodontitis, their role in the disease remains elusive. Using a bacterial-induced model of murine periodontitis, we revealed a prolonged elevation in IFN-I expressio
Externí odkaz:
https://doaj.org/article/56908d35db2e48858ae0d577b6efde41
Autor:
Maria Nassar, Yaara Tabib, Tal Capucha, Gabriel Mizraji, Tsipora Nir, Faris Saba, Rana Salameh, Luba Eli-Berchoer, Asaf Wilensky, Tal Burstyn-Cohen, Avi-Hai Hovav
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Growth arrest-specific 6 (GAS6) expressed by oral epithelial cells and dendritic cells (DCs) was shown to play a critical role in the maintenance of oral mucosal homeostasis. In this study, we demonstrate that the induction of pathogen-specific oral
Externí odkaz:
https://doaj.org/article/136a577953a544a68f83ff77f2d00c5e
Autor:
Karina Furmanov, Mazal Elnekave, Abdallah Sa'eed, Hadas Segev, Luba Eli-Berchoer, Darrell N Kotton, Gilad Bachrach, Avi-Hai Hovav
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66488 (2013)
Memory CD8(+) T lymphocytes play a central role in protective immunity. In attempt to increase the frequencies of memory CD8(+) T cells, repeated immunizations with viral vectors are regularly explored. Lentivectors have emerged as a powerful vaccine
Externí odkaz:
https://doaj.org/article/41fa69051e6c4e0e8e9fdfe8559943ea
Autor:
Asaf Wilensky, Y. Jaber, A. Leibovich, O Barel, Khaled Zubeidat, Yuval Aizenbud, Luba Eli-Berchoer, Immo Prinz, O. Heyman, Yaara Tabib, Y. Horev, Avi-Hai Hovav, Yasmin Saba
Publikováno v:
Journal of Dental Research. 101:428-436
γδ T cells are nonclassical T lymphocytes representing the major T-cell population at epithelial barriers. In the gingiva, γδ T cells are enriched in epithelial regions adjacent to the biofilm and are considered to regulate local immunity to main
Autor:
Yasmin Saba, Itay Aizenbud, Daniela Matanes, Noam Koren, Or Barel, Khalid Zubeidat, Tal Capucha, Eyal David, Luba Eli-Berchoer, Patrizia Stoitzner, Asaf Wilensky, Ido Amit, Rakefet Czerninski, Simon Yona, Avi-Hai Hovav
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Oral cancer is often diagnosed at late stages, resulting in a poor prognosis of this disease. Understanding early carcinogenic events taking place during the development of oral cancer is, therefore, an important unmet clinical need. Thi
Autor:
Howard B. Gutstein, Omer Barkai, Luba Eli-Berchoer, Ben Title, Alexander M. Binshtok, Stephanie Puig, Shaya Lev, Ben Katz
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. Our work reveals that the platelet-derived growth factor-BB, by inhibiting nociceptive M-type potassium channels, acts as a pain-inducing proinflammatory factor that significantly contributes to
Autor:
Adi Binder Gallimidi, JebaMercy Gnanasekaran, Alaa Daoud, Arin Khashan, Sarah Angabo, Gabriel Nussbaum, Karthikeyan Pandi, Hasna A Makkawi, Michael Elkin, Luba Eli Berchoer, Elias Saba, Esther Hermano
Publikováno v:
Cancers
Volume 12
Issue 8
Cancers, Vol 12, Iss 2331, p 2331 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2331, p 2331 (2020)
Porphyromonas gingivalis is a member of the dysbiotic oral microbiome associated with oral inflammation and periodontal disease. Intriguingly, epidemiological studies link P. gingivalis to an increased risk of pancreatic cancer. Given that oral bacte