Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Luanne M, Metz"'
Autor:
Catharina J. A. Romme, Emma A. M. Stanley, Pauline Mouches, Matthias Wilms, G. Bruce Pike, Luanne M. Metz, Nils D. Forkert
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionThe rate of neurodegeneration in multiple sclerosis (MS) is an important biomarker for disease progression but can be challenging to quantify. The brain age gap, which quantifies the difference between a patient's chronological and their
Externí odkaz:
https://doaj.org/article/401f983d703e4c49923d99c9f040be23
Autor:
Jiwon Oh, Nathalie Arbour, Fabrizio Giuliani, Melanie Guenette, Shannon Kolind, Larry Lynd, Ruth Ann Marrie, Luanne M. Metz, Alexandre Prat, Alice Schabas, Penelope Smyth, Roger Tam, Anthony Traboulsee, Voon Wee Yong, Scott B. Patten
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Disease progression is observed across the spectrum of people with multiple sclerosis (MS) and identification of effective treatment strategies to halt progression remains one of the greatest unmet clinical needs. Objectives: The Canadian
Externí odkaz:
https://doaj.org/article/20a19b62873a48c5bfdb5748cc4d63f4
Autor:
Zahra Hosseinpour, Olayinka Oladosu, Wei-qiao Liu, G. Bruce Pike, V. Wee Yong, Luanne M. Metz, Yunyan Zhang
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Background and goalIn vivo characterization of brain lesion types in multiple sclerosis (MS) has been an ongoing challenge. Based on verified texture analysis measures from clinical magnetic resonance imaging (MRI), this study aimed to develop a meth
Externí odkaz:
https://doaj.org/article/ea018a2e98d0456392a6ca17905c1fd3
Autor:
Maryam Tayyab, Luanne M. Metz, David K.B. Li, Shannon Kolind, Robert Carruthers, Anthony Traboulsee, Roger C. Tam
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionMachine learning (ML) has great potential for using health data to predict clinical outcomes in individual patients. Missing data are a common challenge in training ML algorithms, such as when subjects withdraw from a clinical study, leav
Externí odkaz:
https://doaj.org/article/91aced3148274eb3aa8d5074ee234ee2
Autor:
Julie Petrin, Ruth Ann Marrie, Virginia Devonshire, Draga Jichici, Olinka Hrebicek, Luanne M. Metz, Sarah A. Morrow, Jiwon Oh, Penelope Smyth, Sarah J. Donkers
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveThe literature that has examined healthcare access and needs of the multiple sclerosis (MS) population is limited. Currently, no research has engaged healthcare providers delivering services to this population to examine their perspectives o
Externí odkaz:
https://doaj.org/article/c83648d12648494295ff1084dbe1457d
Autor:
Sarah M. Orton, Amarpreet Sangha, Mehul Gupta, Kristina Martens, Luanne M. Metz, A. P. J. de Koning, Gerald Pfeffer
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Multiple sclerosis (MS) is a chronic debilitating neurological condition with a wide range of phenotype variability. A complex interplay of genetic and environmental factors contributes to disease onset and progression in MS patients. Vitamin D defic
Externí odkaz:
https://doaj.org/article/43770c769a174fb0b2b1d65ed810dbc3
Autor:
Jiwon Oh, Nathalie Arbour, Fabrizio Giuliani, Melanie Guenette, Shannon Kolind, Larry Lynd, Ruth Ann Marrie, Luanne M. Metz, Scott B. Patten, Alexandre Prat, Alice Schabas, Penelope Smyth, Roger Tam, Anthony Traboulsee, V. Wee Yong
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-19 (2021)
Abstract Background Neurological disability progression occurs across the spectrum of people living with multiple sclerosis (MS). Although there are a handful of disease-modifying treatments approved for use in progressive phenotypes of MS, there are
Externí odkaz:
https://doaj.org/article/eb244b7ca06b45aca81b35c146d52676
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
IntroductionDisease development in multiple sclerosis (MS) causes dramatic structural changes, but the exact changing patterns are unclear. Our objective is to investigate the differences in brain structure locally and spatially between relapsing-rem
Externí odkaz:
https://doaj.org/article/e0a80b69706840568fb3bfb505c10766
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Tissue pathology in multiple sclerosis (MS) is highly complex, requiring multi-dimensional analysis. In this study, our goal was to test the feasibility of obtaining high angular resolution diffusion imaging (HARDI) metrics through single-shell model
Externí odkaz:
https://doaj.org/article/b3cb13252f8848bbb839508d030b955a
Autor:
Kirsten M. Fiest, Jamie Greenfield, Luanne M. Metz, Scott B. Patten, Nathalie Jetté, Ruth Ann Marrie
Publikováno v:
Health and Quality of Life Outcomes, Vol 15, Iss 1, Pp 1-9 (2017)
Abstract Background Though many people with multiple sclerosis (MS) have comorbidities, the use of generic and disease-specific health related quality of life (HRQOL) scales to discriminate the effects of comorbidity has not been established. The uti
Externí odkaz:
https://doaj.org/article/4989d7daeabb492c9385d0ed5db28732