Zobrazeno 1 - 10
of 968
pro vyhledávání: '"Luan T"'
Autor:
Sheng-You Liao, Dmytro Rudoy, Sander B. Frank, Luan T. Phan, Olga Klezovitch, Julian Kwan, Ilsa Coleman, Michael C. Haffner, Dapei Li, Peter S. Nelson, Andrew Emili, Valeri Vasioukhin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract SND1 and MTDH are known to promote cancer and therapy resistance, but their mechanisms and interactions with other oncogenes remain unclear. Here, we show that oncoprotein ERG interacts with SND1/MTDH complex through SND1’s Tudor domain. E
Externí odkaz:
https://doaj.org/article/4403e3302e9b4f26a416658e94332b3c
Publikováno v:
Journal of Inflammation Research, Vol Volume 16, Pp 5309-5326 (2023)
Jiaming He,1,2,* Tiankuo Luan,3,* Gang Zhao,4 Yingxue Yang5 1Laboratory of Stem Cells and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Institute of
Externí odkaz:
https://doaj.org/article/a5a10d96845341a99988c0430ab3ce0f
Publikováno v:
Journal of Inflammation Research, Vol Volume 16, Pp 3837-3852 (2023)
Tiankuo Luan,1,* Xian Yang,2,* Ge Kuang,1 Ting Wang,3 Jiaming He,1 Zhibo Liu,3 Xia Gong,1 Jingyuan Wan,2 Ke Li4 1Department of Anatomy, Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Pharmacology, Chongq
Externí odkaz:
https://doaj.org/article/e087d4459dd64fb2aa86adc135d6e5d1
Autor:
Ana Potic, Stefanie Perrier, Tijana Radovic, Svetlana Gavrilovic, Jelena Ostojic, Luan T. Tran, Isabelle Thiffault, Tomi Pastinen, Raphael Schiffmann, Geneviève Bernard
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-17 (2023)
Abstract Background Neurodegeneration due to cerebral folate transport deficiency is a rare autosomal recessive disorder caused by biallelic pathogenic variants in FOLR1. Onset typically occurs in late infancy and is characterized by psychomotor regr
Externí odkaz:
https://doaj.org/article/069bc339519c472a91b38f2db7cff481
Autor:
Julia Macintosh, Stefanie Perrier, Maxime Pinard, Luan T. Tran, Kether Guerrero, Chitra Prasad, Asuri N. Prasad, Tomi Pastinen, Isabelle Thiffault, Benoit Coulombe, Geneviève Bernard
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
RNA polymerase III-related leukodystrophy (POLR3-related leukodystrophy) is a rare, genetically determined hypomyelinating disease arising from biallelic pathogenic variants in genes encoding subunits of RNA polymerase III (Pol III). Here, we describ
Externí odkaz:
https://doaj.org/article/29e8d5ae09184e7c941a524a3255f883
Autor:
Stefanie Perrier, Kether Guerrero, Luan T. Tran, Mackenzie A. Michell-Robinson, Geneviève Legault, Bernard Brais, Michel Sylvain, James Dorman, Michelle Demos, Wolfgang Köhler, Tomi Pastinen, Isabelle Thiffault, Geneviève Bernard
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionRare neurodevelopmental disorders, including inherited white matter disorders or leukodystrophies, often present a diagnostic challenge on a genetic level given the large number of causal genes associated with a range of disease subtypes.
Externí odkaz:
https://doaj.org/article/f1fdff3b504e41b18a02f8a168cfe29e
Publikováno v:
Cancer Management and Research, Vol Volume 13, Pp 8157-8167 (2021)
Ran Zhang,1,2 Ranran Zhang,3 Ting Luan,4,5 Biwei Liu,6 Yimei Zhang,6 Yaping Xu,1 Xiaorong Sun,5 Ligang Xing6 1Department of Radiation Oncology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of China
Externí odkaz:
https://doaj.org/article/e1747076a6b64e339b0a2f9c8513d030
Autor:
Aaron Spahr, Zaliqa Rosli, Mélanie Legault, Luan T. Tran, Simon Fournier, Helia Toutounchi, Lama Darbelli, Cécile Madjar, Cassandra Lucia, Marie-Lou St-Jean, Samir Das, Alan C. Evans, Geneviève Bernard
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background Rare diseases are estimated to affect 150–350 million people worldwide. With advances in next generation sequencing, the number of known disease-causing genes has increased significantly, opening the door for therapy development
Externí odkaz:
https://doaj.org/article/458e89caa53041649c3cf15c4c13ae3b
Autor:
Alexa Derksen, Hung-Yu Shih, Diane Forget, Lama Darbelli, Luan T. Tran, Christian Poitras, Kether Guerrero, Sundaresan Tharun, Fowzan S. Alkuraya, Wesam I. Kurdi, Cam-Tu Emilie Nguyen, Anne-Marie Laberge, Yue Si, Marie-Soleil Gauthier, Joshua L. Bonkowsky, Benoit Coulombe, Geneviève Bernard
Publikováno v:
HGG Advances, Vol 2, Iss 3, Pp 100034- (2021)
Summary: Leukodystrophies, genetic neurodevelopmental and/or neurodegenerative disorders of cerebral white matter, result from impaired myelin homeostasis and metabolism. Numerous genes have been implicated in these heterogeneous disorders; however,
Externí odkaz:
https://doaj.org/article/5f90d21d2bce448496c47a87b96f7a5f
Autor:
Jennifer Friedman, Desiree E. Smith, Mahmoud Y. Issa, Valentina Stanley, Rengang Wang, Marisa I. Mendes, Meredith S. Wright, Kristen Wigby, Amber Hildreth, John R. Crawford, Alanna E. Koehler, Shimul Chowdhury, Shareef Nahas, Liting Zhai, Zhiwen Xu, Wing-Sze Lo, Kiely N. James, Damir Musaev, Andrea Accogli, Kether Guerrero, Luan T. Tran, Tarek E. I. Omar, Tawfeg Ben-Omran, David Dimmock, Stephen F. Kingsmore, Gajja S. Salomons, Maha S. Zaki, Geneviève Bernard, Joseph G. Gleeson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Valyl-tRNA synthetase (VARS) charges valyl-tRNA with the amino acid valine, required for translation. Here, the authors describe a progressive epileptic encephalopathy in individuals from five families carrying biallelic mutations in the VARS gene th
Externí odkaz:
https://doaj.org/article/2b11aa05a4174343ac7596764303089f