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FDA Approval Summary: Asciminib for Ph+ CML in Chronic Phase Treated with Two or More Tyrosine Kinase Inhibitors and for the T315I Mutation.

Autor: Pamuk GE; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Chow ECY; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Ionan AC; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Chen H; Office of Biostatistics, Office of Translational Science, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Lee SL; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Hsu V; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Grimstein M; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Zheng N; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Sun J; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Charlab R; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Gehrke BJ; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Vallejo J; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Ehrlich LA; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., de Claro RA; Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland., Theoret MR; Oncology Center of Excellence, U.S. Food and Drug Administration, Silver Spring, Maryland.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Oct 01; Vol. 30 (19), pp. 4266-4271.

Beyond Blood Clotting: The Many Roles of Platelet-Derived Extracellular Vesicles.

Autor: Muttiah B; Department of Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia., Ng SL; Department of Craniofacial Diagnostics and Biosciences, Faculty of Dentistry, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia., Lokanathan Y; Department of Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia., Ng MH; Department of Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia., Law JX; Department of Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur 56000, Malaysia.

Publikováno v: Biomedicines [Biomedicines] 2024 Aug 14; Vol. 12 (8). Date of Electronic Publication: 2024 Aug 14.

Experience of Patients With Heroin Addiction Receiving Methadone Maintenance Treatment in Community Settings in Taiwan.

Autor: Shih MH; MSN, RN, Department of Nursing, Lukang Christian Hospital, Changhua, Taiwan., Hsu WY; BSc, Psychiatrist, Department of Psychiatry, Changhua Christian Hospital, Changhua, Taiwan., Siao CL; MSN, RN, Department of Nursing, Changhua Christian Hospital, Changhua, Taiwan., Lee LH; PhD, RN, Associate Professor, Department of Nursing, Hungkuang University, Taichung, Taiwan., Chen SL; PhD, RN, Professor, Department of Nursing, Hungkuang University, Taichung, Taiwan., Tsay SL; PhD, RN, Professor, Department of Nursing, Da-Yeh University, Changhua, Taiwan., Yang CI; PhD, RN, Professor, Department of Nursing, Hungkuang University, Taichung, Taiwan.

Publikováno v: The journal of nursing research : JNR [J Nurs Res] 2024 Aug 01; Vol. 32 (4), pp. e342. Date of Electronic Publication: 2024 Aug 01.

Mef2d potentiates type-2 immune responses and allergic lung inflammation.

Autor: Szeto ACH; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Clark PA; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Ferreira ACF; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Heycock M; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Griffiths EL; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Jou E; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Mannion J; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Luan SL; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Storrar S; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Knolle MD; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.; Cambridge University Hospitals, Cambridge, CB2 0QQ, UK., Kozik P; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Jolin HE; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Fallon PG; School of Medicine, Trinity College Dublin, Dublin, Ireland., McKenzie ANJ; MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.

Publikováno v: Science (New York, N.Y.) [Science] 2024 Jun 28; Vol. 384 (6703), pp. eadl0370. Date of Electronic Publication: 2024 Jun 28.