Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Luan H. Phan"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
CD73, a cell surface 5′nucleotidase that generates adenosine, has emerged as an attractive therapeutic target for reprogramming cancer cells and the tumor microenvironment to dampen antitumor immune cell evasion. Decades of studies have paved the w
Externí odkaz:
https://doaj.org/article/cbe8470037244e86abe70c82e9e981c3
Autor:
Russell Broaddus, Christine V. Chung, Jessica L. Bowser, Rebecca C. Kazen, Jiping Feng, Ashley Draisey, Su Su Xie, Jerry B. Harvey, Luan H. Phan, Katherine C. Kurnit
Publikováno v:
Cancer Lett
In many tumors, CD73 (NT5E), a rate-limiting enzyme in adenosine biosynthesis, is upregulated by TGF-β and drives tumor progression. Conversely, CD73 is downregulated in endometrial carcinomas (EC) despite a TGF-β-rich environment. Through gene exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4648fc831b10c088eba140eeea011bb4
https://pubmed.ncbi.nlm.nih.gov/33609609
https://pubmed.ncbi.nlm.nih.gov/33609609
Autor:
Russell Broaddus, Jerry B. Harvey, Andrew B. Gladden, SuSu Xie, Pierre D. McCrea, Luan H. Phan, Katherine C. Kurnit, Jiping Feng, Jessica L. Bowser
Publikováno v:
Clinical Cancer Research. 27:PR005-PR005
Somatic missense mutations in exon 3 of CTNNB1 are associated with significantly worse recurrence-free survival in patients with low grade, early stage endometrioid-type endometrial carcinoma (EEC). CTNNB1 encodes for β-catenin, an integral protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71960e4ea2ec07b6bb9d3fb9466e4dd0
https://doi.org/10.1158/1557-3265.endomet20-pr005
https://doi.org/10.1158/1557-3265.endomet20-pr005
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
CD73, a cell surface 5′nucleotidase that generates adenosine, has emerged as an attractive therapeutic target for reprogramming cancer cells and the tumor microenvironment to dampen antitumor immune cell evasion. Decades of studies have paved the w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d691a8a55b7c32626dcaac19345037
https://pubmed.ncbi.nlm.nih.gov/32351498
https://pubmed.ncbi.nlm.nih.gov/32351498
Intestinal inflammation is a key element in inflammatory bowel disease and is related to a combination of factors, including genetics, mucosal barrier dysfunction, bacteria translocation, deleterious host–microbe interactions, and dysregulated immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e7f020a3b12ba4e641e9152e2f33ec
https://europepmc.org/articles/PMC5784778/
https://europepmc.org/articles/PMC5784778/
Publikováno v:
Frontiers in Immunology; 4/15/2020, p1-26, 26p