Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Luai Huleihel"'
Autor:
Christian L. Lino Cardenas, Chase W. Kessinger, Yisha Cheng, Carolyn MacDonald, Thomas MacGillivray, Brian Ghoshhajra, Luai Huleihel, Saifar Nuri, Ashish S. Yeri, Farouc A. Jaffer, Naftali Kaminski, Patrick Ellinor, Neal L. Weintraub, Rajeev Malhotra, Eric M. Isselbacher, Mark E. Lindsay
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Vascular smooth muscle cell (VSMC) dysfunction is a common feature of thoracic aortic aneurysms (TAAs). Here, Lino Cardenas and colleagues show that the formation of a HDAC9-MALAT1-BRG1 complex promotes VSMC dysfunction in TAA by epigenetically alter
Externí odkaz:
https://doaj.org/article/0dcceeceb2e54494ba608f97eb0c0490
Autor:
Ali H Zaidi, Lindsey T Saldin, Lori A Kelly, Linda Bergal, Ricardo Londono, Juliann E Kosovec, Yoshihiro Komatsu, Pashtoon M Kasi, Amit A Shetty, Timothy J Keane, Shyam J Thakkar, Luai Huleihel, Rodney J Landreneau, Stephen F Badylak, Blair A Jobe
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122375 (2015)
To establish a miRNA signature for metastasis in an animal model of esophageal adenocarcinoma (EAC).The incidence of esophageal adenocarcinoma (EAC) has dramatically increased and esophageal cancer is now the sixth leading cause of cancer deaths worl
Externí odkaz:
https://doaj.org/article/0097ed5a30e04d27aff9976e8ac20dc8
Autor:
Claudia Coronnello, Ryan Hartmaier, Arshi Arora, Luai Huleihel, Kusum V Pandit, Abha S Bais, Michael Butterworth, Naftali Kaminski, Gary D Stormo, Steffi Oesterreich, Panayiotis V Benos
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 12, p e1002830 (2012)
MicroRNAs (miRNAs) are post-transcriptional regulators that bind to their target mRNAs through base complementarity. Predicting miRNA targets is a challenging task and various studies showed that existing algorithms suffer from high number of false p
Externí odkaz:
https://doaj.org/article/339303221d764941b8c095c5b2d6688a
Autor:
Yuan-Pu Peter Di, Xiaoping Zhang, Qiao Lin, Nathaniel T. Remlinger, Chia-Hsin Liu, Dandan Yang, Luai Huleihel, Thomas W. Gilbert
Publikováno v:
ACS Biomaterials Science & Engineering. 7:1088-1099
Escherichiacoli has become the prominent cause of nosocomial pneumonia in recent years. In the meantime, some strains of E. coli have developed resistance to commonly used antibacterial drugs. The urinary bladder matrix (UBM) is a biologically derive
Autor:
Nicholas G. Smith, Lindsey T. Saldin, Luai Huleihel, Neill J. Turner, Ali H. Zaidi, Christopher C. Chung, Ashten N. Omstead, Xue Li, Anant K. Bajwa, David Nascari, Li Zhang, Lina M. Quijano, Shil Patel, George S. Hussey, Juliann E. Kosovec, Blair A. Jobe, Divya Raghu, Stephen F. Badylak
Publikováno v:
Tissue Engineering Part A. 25:487-498
Extracellular matrix (ECsM) bioscaffolds have been successfully used to treat five esophageal adenocarcinoma (EAC) patients following resection of neoplastic mucosal tissue. The present study evaluated the in vitro effect of ECM harvested from nonmal
Autor:
Maor Sauler, Sara Khanal, Naiqian Niu, Clemente J. Britto, Lauren Cohn, Alison Thompson, Martin D. Slade, Jose D. Herazo-Maya, Lokesh Sharma, Luai Huleihel, Charles S. Dela Cruz, Naftali Kaminski
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 316:L321-L333
Bpifa1 (BPI fold-containing group A member 1) is an airway host-protective protein with immunomodulatory properties that binds to LPS and is regulated by infectious and inflammatory signals. Differential expression of Bpifa1 has been widely reported
Autor:
Liam Chung, Mary Ann Stepp, Matthew T. Wolf, Alexander F. Chin, David R. Maestas, Joshua Hooks, Xiaokun Wang, Andriana Lebid, Franck Housseau, Nathaniel T. Remlinger, James I. Andorko, Jennifer H. Elisseeff, Luai Huleihel
Publikováno v:
Science Advances
Extracellular matrix particulate stimulates local and peripheral type 2 immune response to enhance corneal wound healing.
The avascular nature of cornea tissue limits its regenerative potential, which may lead to incomplete healing and formation
The avascular nature of cornea tissue limits its regenerative potential, which may lead to incomplete healing and formation
Autor:
Qiao, Lin, Xiaoping, Zhang, Dandan, Yang, Chia-Hsin, Liu, Luai, Huleihel, Nathaniel, Remlinger, Thomas, Gilbert, Yuan-Pu Peter, Di
Publikováno v:
ACS biomaterials scienceengineering. 7(3)
Autor:
Elisabeth L. Gill, Yan Yan Shery Huang, Francesco Simone Ruggeri, Iek Man Lei, Simon C. Satchell, Natasha S. Lewis, Tuomas P. J. Knowles, Jack Tuffin, Zhaoying Li, Luai Huleihel, Stephen F. Badylak, Gavin I. Welsh, Thierry Savin, Moin A. Saleem
Publikováno v:
Acta Biomaterialia, 78, 111-122
Acta Biomaterialia 78 (2018)
Li, Z, Tuffin, J, Lei, I M, Ruggeri, F S, Lewis, N S, Gill, E L, Savin, T, Huleihel, L, Badylak, S F, Knowles, T, Satchell, S, Welsh, G, Saleem, M & Shery Huang, Y Y 2018, ' Solution fibre spinning technique for the fabrication of tuneable decellularised matrix-laden fibres and fibrous micromembranes ', Acta Biomaterialia, vol. 78, pp. 111-122 . https://doi.org/10.1016/j.actbio.2018.08.010
Acta Biomaterialia
Acta Biomaterialia 78 (2018)
Li, Z, Tuffin, J, Lei, I M, Ruggeri, F S, Lewis, N S, Gill, E L, Savin, T, Huleihel, L, Badylak, S F, Knowles, T, Satchell, S, Welsh, G, Saleem, M & Shery Huang, Y Y 2018, ' Solution fibre spinning technique for the fabrication of tuneable decellularised matrix-laden fibres and fibrous micromembranes ', Acta Biomaterialia, vol. 78, pp. 111-122 . https://doi.org/10.1016/j.actbio.2018.08.010
Acta Biomaterialia
Recreating tissue-specific microenvironments of the extracellular matrix (ECM) in vitro is of broad interest for the fields of tissue engineering and organ-on-a-chip. Here, we present biofunctional ECM protein fibres and suspended membranes, with tun
Autor:
Stephen F. Badylak, Luai Huleihel, Jenna L. Dziki, Yasumoto Matsumura, Yang Zhu, Ricardo Lodono, Leah C. Fuhrman, Hongbin Jiang, William R. Wagner, Gabriela N.F. Faria, Sato Hideyoshi, Samuel T. LoPresti
Publikováno v:
Acta Biomaterialia. 73:112-126
Biodegradable injectable hydrogels have been extensively studied and evaluated in various medical applications such as for bulking agents, drug delivery reservoirs, temporary barriers, adhesives, and cell delivery matrices. Where injectable hydrogels