Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Lu-yun LIAN"'
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Galectins are involved in the regulation of divergent physiological and pathological processes and are increasingly recognized to play important roles in a number of diseases. However, a simple and effective way in assessing galectin-ligand
Externí odkaz:
https://doaj.org/article/030c40846b0749f9815431bef71e56dd
Autor:
Lisa Luu, Germanus S. Bah, Ndode Herman Okah-Nnane, Catherine S. Hartley, Alexandra F. Glover, Tessa R. Walsh, Lu-Yun Lian, Bin Zhan, Maria Elena Bottazzi, David Abraham, Nikolai Petrovsky, Nicolas Bayang, Bernard Tangwa, Rene Billingwe Ayiseh, Glory Enjong Mbah, David D. Ekale, Vincent N. Tanya, Sara Lustigman, Benjamin L. Makepeace, John Graham-Brown
Publikováno v:
Vaccines, Vol 10, Iss 6, p 861 (2022)
Onchocerciasis (river blindness), caused by the filarial nematode Onchocerca volvulus, is a neglected tropical disease mainly of sub-Saharan Africa. Worldwide, an estimated 20.9 million individuals live with infection and a further 205 million are at
Externí odkaz:
https://doaj.org/article/50a1373c156e48e18dca51fca88b9831
Autor:
Bin Zhan, Sridhar Arumugam, Malcolm W Kennedy, Nancy Tricoche, Lu-Yun Lian, Oluwatoyin A Asojo, Sasisekhar Bennuru, Maria Elena Bottazzi, Peter J Hotez, Sara Lustigman, Thomas R Klei
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 10, p e0006772 (2018)
Parasitic nematodes produce an unusual class of fatty acid and retinol (FAR)-binding proteins that may scavenge host fatty acids and retinoids. Two FARs from Brugia malayi (Bm-FAR-1 and Bm-FAR-2) were expressed as recombinant proteins, and their liga
Externí odkaz:
https://doaj.org/article/be720cd2deef495e82184ab8a43694e8
Structure of the Neisseria Adhesin Complex Protein (ACP) and its role as a novel lysozyme inhibitor.
Autor:
María Victoria Humbert, Amaka Marian Awanye, Lu-Yun Lian, Jeremy P Derrick, Myron Christodoulides
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006448 (2017)
Pathogenic and commensal Neisseria species produce an Adhesin Complex Protein, which was first characterised in Neisseria meningitidis (Nm) as a novel surface-exposed adhesin with vaccine potential. In the current study, the crystal structure of a re
Externí odkaz:
https://doaj.org/article/852597b45ac14534a0fa348f78c4ef37
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108415 (2014)
Mouse urine contains highly polymorphic major urinary proteins that have multiple functions in scent communication through their abilities to bind, transport and release hydrophobic volatile pheromones. The mouse genome encodes for about 20 of these
Externí odkaz:
https://doaj.org/article/7768cb019341432b9db33a0ffce4d747
Autor:
Jamie-Lee Berry, Marie M Phelan, Richard F Collins, Tomas Adomavicius, Tone Tønjum, Stefan A Frye, Louise Bird, Ray Owens, Robert C Ford, Lu-Yun Lian, Jeremy P Derrick
Publikováno v:
PLoS Pathogens, Vol 8, Iss 9, p e1002923 (2012)
Type IV pili are polymeric fibers which protrude from the cell surface and play a critical role in adhesion and invasion by pathogenic bacteria. The secretion of pili across the periplasm and outer membrane is mediated by a specialized secretin prote
Externí odkaz:
https://doaj.org/article/c5dfad14645e482ebefde8203a97758d
Autor:
Andrew P Herbert, Michèle Riesen, Leanne Bloxam, Effie Kosmidou, Brian M Wareing, James R Johnson, Marie M Phelan, Stephen R Pennington, Lu-Yun Lian, Alan Morgan
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41975 (2012)
Dietary restriction (DR) extends lifespan in yeast, worms, flies and mammals, suggesting that it may act via conserved processes. However, the downstream mechanisms by which DR increases lifespan remain unclear. We used a gel based proteomic strategy
Externí odkaz:
https://doaj.org/article/be45795622ff4271bf7d2f40477e52d3
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20574 (2011)
NADPH-cytochrome P450 oxidoreductase (CPR) plays a central role in chemical detoxification and insecticide resistance in Anopheles gambiae, the major vector for malaria. Anopheles gambiae CPR (AgCPR) was initially expressed in Eschericia coli but fai
Externí odkaz:
https://doaj.org/article/c078b1c8cc5248999abac58d0c0db96f
Autor:
Lu-Yun Lian, Sravan R Pandalaneni, Pryank Patel, Hannah V McCue, Lee P Haynes, Robert D Burgoyne
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27779 (2011)
NCS-1 is a member of the neuronal calcium sensor (NCS) family of EF-hand Ca(2+) binding proteins which has been implicated in several physiological functions including regulation of neurotransmitter release, membrane traffic, voltage gated Ca(2+) cha
Externí odkaz:
https://doaj.org/article/7663008eff6b46ef85e295f245f701a2
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10534 (2010)
Neuronal calcium sensor-1 (NCS-1) is a Ca(2+) sensor protein that has been implicated in the regulation of various aspects of neuronal development and neurotransmission. It exerts its effects through interactions with a range of target proteins one o
Externí odkaz:
https://doaj.org/article/220cc48e786c490bbdbb9404cb4b02ee