Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lu-yong Wang"'
Publikováno v:
Genome Research. 19:106-117
Genome structural variation includes segmental duplications, deletions, and other rearrangements, and array-based comparative genomic hybridization (array-CGH) is a popular technology for determining this. Drawing relevant conclusions from array-CGH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24b2025b8f11d199e68d23b084359be
https://doi.org/10.1101/gr.080069.108
https://doi.org/10.1101/gr.080069.108
Autor:
Michael Snyder, Anthony R. Borneman, Michael Seringhaus, Zhengdong D. Zhang, Haiyuan Yu, Lu Yong Wang, Joel Rozowsky, Mark Gerstein, Tara A. Gianoulis
Publikováno v:
Science. 317:815-819
Characterization of interspecies differences in gene regulation is crucial for understanding the molecular basis of both phenotypic diversity and evolution. By means of chromatin immunoprecipitation and DNA microarray analysis, the divergence in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d3dcb177d5e29567ffc1048756e5b7
https://doi.org/10.1126/science.1140748
https://doi.org/10.1126/science.1140748
Publikováno v:
Journal of Computational Biology. 13:1673-1684
Although there has been great success in identifying disease genes for simple, monogenic Mendelian traits, deciphering the genetic mechanisms involved in complex diseases remains challenging. One major approach is to identify configurations of intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8dbfa62a9dc629086794e825dc8706
https://doi.org/10.1089/cmb.2006.13.1673
https://doi.org/10.1089/cmb.2006.13.1673
Autor:
Lu-yong Wang, An-Suei Yang
Publikováno v:
Bioinformatics. 19:1267-1274
Motivation: A large body of experimental and theoretical evidence suggests that local structural determinants are frequently encoded in short segments of protein sequence. Although the local structural information, once recognized, is particularly us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac5cd4510dac464e2b954c705a1dd19
https://doi.org/10.1093/bioinformatics/btg151
https://doi.org/10.1093/bioinformatics/btg151
Autor:
Lu-Yong Wang, Zhuowen Tu
Publikováno v:
EMBC
The optimal treatment of patients with complex diseases, such as cancers, depends on the accurate diagnosis by using a combination of clinical and histopathological data. In many scenarios, it becomes tremendously difficult because of the limitations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd107caad1d3ac676912b2ceccbd2055
https://pubmed.ncbi.nlm.nih.gov/17947173
https://pubmed.ncbi.nlm.nih.gov/17947173
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783540730590
Systems Biology and Computational Proteomics
Systems Biology and Computational Proteomics
Mass spectrometry (MS) is becoming a popular approach for quantifying the protein composition of complex samples. A great challenge for comparative proteomic profiling is to match corresponding peptide features from different experiments to ensure th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a641bc7d14ac37c6cb470647303ad76a
https://doi.org/10.1007/978-3-540-73060-6_9
https://doi.org/10.1007/978-3-540-73060-6_9
Publikováno v:
CSB Workshops
Clinical proteomics is an emerging field that will have great impact on molecular diagnosis, identification of disease biomarkers, drug discovery and clinical trials in the post-genomic era. Protein profiling in tissues and fluids in disease and path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::328ab35d9ccdd09d64461fe0121cc3bb
https://doi.org/10.1109/csbw.2005.51
https://doi.org/10.1109/csbw.2005.51
Publikováno v:
CSB Workshops
DNA microarray experiments generate a substantial amount of information about global gene expression. Gene expression profiles can be represented as points in multi-dimensional space. It is essential to identify relevant groups of genes in biomedical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbe064a21df3c149cf162ec3a1925fe5
https://doi.org/10.1109/csbw.2005.66
https://doi.org/10.1109/csbw.2005.66
Autor:
Daniel P. Fasulo, Lu-Yong Wang
Publikováno v:
EMBC
Genome-wide association study for complex diseases will generate massive amount of single nucleotide polymorphisms (SNPs) data. Univariate statistical test (i.e. Fisher exact test) was used to single out non-associated SNPs. However, the disease-susc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b77eacfb40e6398544b892f049e316
https://doi.org/10.1109/iembs.2006.260585
https://doi.org/10.1109/iembs.2006.260585
Publikováno v:
Scopus-Elsevier
Clinical proteomics is an emerging field that will have great impact on molecular diagnosis, identification of disease biomarkers, drug discovery and clinical trials in the post-genomic era. Protein profiling in tissues and fluids in disease and path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75db55dca41bd575ce1f52c59dabc1f2
https://doi.org/10.1109/iembs.2005.1615538
https://doi.org/10.1109/iembs.2005.1615538