Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lu-xing Pan"'
Autor:
Guorong Xu, Hai Li, Lu-xing Pan, Quan Shang, Akira Honda, M. Ananthanarayanan, Sandra K. Erickson, Benjamin L. Shneider, Sarah Shefer, Jaya Bollineni, Barry M. Forman, Yasushi Matsuzaki, Frederick J. Suchy, G. Stephen Tint, Gerald Salen
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 10, Pp 1956-1962 (2003)
We investigated how cholesterol feeding regulates cholesterol 7α-hydroxylase (CYP7A1) via the nuclear receptors farnesoid X receptor (FXR) and liver X receptor α (LXRα) in New Zealand white rabbits. After 1 day of 2% cholesterol feeding, when the
Externí odkaz:
https://doaj.org/article/837a8425f81549c1ab7fa240a891686f
Autor:
Guorong Xu, Lu-xing Pan, Sandra K. Erickson, Barry M. Forman, Benjamin L. Shneider, M. Ananthanarayanan, Xiaogui Li, Sarah Shefer, N. Balasubramanian, Lin Ma, Hitoshi Asaoka, Steven R. Lear, Lien B. Nguyen, Isabelle Dussault, Frederick J. Suchy, G. Stephen Tint, Gerald Salen
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 1, Pp 45-50 (2002)
We investigated the role of the orphan nuclear receptor farnesoid X receptor (FXR) in the regulation of cholesterol 7α-hydroxylase (CYP7A1), using an in vivo rabbit model, in which the bile acid pool, which includes high affinity ligands for FXR, wa
Externí odkaz:
https://doaj.org/article/cfdfe43fe9f444c8937c82ae74f94e34
Autor:
Monica Saumoy, John Y.L. Chiang, Guorong Xu, Gerald Salen, Quan Shang, Lu-xing Pan, G. Stephen Tint
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 293:G817-G823
The aim of this study was to explore why in rabbits activation of farnesoid X receptor (FXR) is dominant over activated liver X receptor-alpha (LXRalpha) in the regulation of CYP7A1. We cloned the rabbit CYP7A1 promoter and found a fetoprotein transc
Autor:
Guorong Xu, John Y.L. Chiang, Frank Chen, Gerald Salen, Hai Li, Meenakshisundaram Ananthanarayanan, Benjamin L. Shneider, Quan Shang, Lu-xing Pan, G. Stephen Tint, Barry M. Forman
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 288:G60-G66
The regulation of the rabbit apical sodium-dependent bile acid transporter (ASBT) was studied both in vivo and in vitro. New Zealand White rabbits were fed 0.5% deoxycholic acid (DCA) or SC-435, a competitive ASBT inhibitor, for 1 wk. In DCA-fed rabb
Autor:
Lu-xing Pan, Sarah Shefer, Guorong Xu, Yasushi Matsuzaki, G. Stephen Tint, Jaya Bollineni, Gerald Salen, Quan Shang, Akira Honda, Hai Li
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 286:G730-G735
Cholesterol feeding upregulates CYP7A1 in rats but downregulates CYP7A1 in rabbits. To clarify the mechanism responsible for the upregulation of CYP7A1 in cholesterol-fed rats, the effects of dietary cholesterol (Ch) and cholic acid (CA) on the activ
Autor:
Yasushi Matsuzaki, Sandra K. Erickson, Akira Honda, Benjamin L. Shneider, Meenakshisundaram Ananthanarayanan, Gerald Salen, Sarah Shefer, Guorong Xu, Quan Shang, Barry M. Forman, Hai Li, Jaya Bollineni, Lu-xing Pan, G. Stephen Tint, Frederick J. Suchy
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 10, Pp 1956-1962 (2003)
We investigated how cholesterol feeding regulates cholesterol 7alpha-hydroxylase (CYP7A1) via the nuclear receptors farnesoid X receptor (FXR) and liver X receptor alpha (LXRalpha) in New Zealand white rabbits. After 1 day of 2% cholesterol feeding,
Autor:
Frederick J. Suchy, G. Stephen Tint, Steven R. Lear, Isabelle Dussault, Gerald Salen, Lu-xing Pan, Meenakshisundaram Ananthanarayanan, Lin Ma, Hitoshi Asaoka, Natarajan Balasubramanian, Lien B. Nguyen, Benjamin L. Shneider, Sandra K. Erickson, Barry M. Forman, Sarah Shefer, Guorong Xu, Xiaogui Li
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 1, Pp 45-50 (2002)
We investigated the role of the orphan nuclear receptor farnesoid X receptor (FXR) in the regulation of cholesterol 7α-hydroxylase (CYP7A1), using an in vivo rabbit model, in which the bile acid pool, which includes high affinity ligands for FXR, wa
Publikováno v:
Journal of Molecular and Cellular Cardiology. 27:2359-2372
Cardiac hypertrophy is characterized, among others, by the molecular events which selectively activate the expression of genes for contractile proteins within individual myocardial cells. As such, myosin light chain 2 (MLC-2), which is upregulated in
Autor:
Ashok K. Batta, John Michel, Lily L. Lai, Lu-xing Pan, Barry M. Forman, Steve Yang, Gerald Salen, Sandra K. Erickson, Tsu-hong Wang, G. Stephen Tint, Jaya Bollineni, Kohei Shimada, Sarah Shefer, Guorong Xu, Jennifer Christie, Hai Li, Richard Tsai
Publikováno v:
The Journal of biological chemistry. 277(52)
We investigated the roles of hydrophobic deoxycholic acid (DCA) and hydrophilic ursocholic acid (UCA) in the regulation of the orphan nuclear farnesoid X receptor (FXR) in vivo. Rabbits with bile fistula drainage (removal of the endogenous bile acid
Autor:
Lu-xing Pan, Hai Li, Quan Shang, Jaya Bollineni, G. Stephen, Sarah Shefer, Guorong Xu, Gerald Salen, Ashok K. Batta
Publikováno v:
Gastroenterology. 124:A159-A160