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Autor:
Hang Zhang, Liang Hao, Lu-Si Rao, Cai-Ping Tan, Zheng-Yin Pan, Zong-Wan Mao, Yue Zheng, Liang-Nian Ji
Publikováno v:
Angewandte Chemie International Edition. 59:18755-18762
The development and malignancy of cancer cells are closely related to the changes of the epigenome. In this work, a mitochondria-targeted rhenium(I) complex (DFX-Re3), integrating the clinical iron chelating agent deferasirox (DFX), has been designed