Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Lu-Ning Sun"'
Autor:
Lu-Ning Sun, Yang Zhao, Zhou-Yi Qian, Xiang-Long Chen, Hong Ma, Yu-Jiao Guo, Hao Shen, Yong-Qing Wang
Publikováno v:
Molecules, Vol 28, Iss 3, p 1205 (2023)
Ibrutinib, orelabrutinib, and zanubrutinib are all Bruton’s tyrosine kinase inhibitors, which have greatly improved the treatment of B-cell malignancies. In this study, an LC-MS/MS method was developed and validated for the determination of orelabr
Externí odkaz:
https://doaj.org/article/6e0ab926602645f7bfa06aaca45bf541
Publikováno v:
Petroleum Science, Vol 17, Iss 2, Pp 477-486 (2019)
Abstract Fracability is a property that indicates how easy reservoir rocks can be fractured in hydraulic fracturing operations. It is a key parameter for fracturing design and evaluation. In order to utilize continuous logging data to predict fracabi
Externí odkaz:
https://doaj.org/article/0b63936e57404c7a8e3d0953973ea129
Autor:
Ning Chen, Lu-Ning Sun, Wen-Hui Hu, Yi-Ya Wang, Li-Jun Xie, Juan Cheng, Hong-Wen Zhang, Yun Liu, Yong-Qing Wang, Li Ding
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
PurposeTo evaluate the tolerability, safety, pharmacokinetics and drug interaction of cefotaxime sodium–tazobactam sodium injection (6:1) in Chinese healthy subjects. The results of the safety and pharmacokinetic studies supported further clinical
Externí odkaz:
https://doaj.org/article/e2a82917535d4403a0e5079571378b61
Autor:
Zi-Qing-Yun Yuan, Chun Qiao, Zhi-Cheng Yang, Lei Yu, Lu-Ning Sun, Yi Qian, Xue-Hui Zhang, Ling Meng, Xiao-Yan Zhang, Yong-Qing Wang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
This study investigated voriconazole (VRC) unbound plasma concentration and its relationship with adverse drug reactions (ADRs) in patients with malignant hematologic disease. Plasma samples were collected from patients or spiked in vitro. A time-sav
Externí odkaz:
https://doaj.org/article/0d7283cbc21148ea92841194fba8efbe
Autor:
Yi Qian, Lu-Ning Sun, Yang-Jie Liu, Qiang Zhang, Jiang-Hao Xu, Zeng-Qing Ma, Xue-Hui Zhang, Hao Xu, Yong-Qing Wang
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Imatinib is a first-line drug for the treatment of gastrointestinal stromal tumors (GIST). This study aims to investigate the influence of different kinds of protein concentrations and genetic polymorphisms of metabolizing enzymes and drug transporte
Externí odkaz:
https://doaj.org/article/52ad7c3fef7146ac976f9900a282772e
Autor:
Lu-Ning Sun, Yang Cao, Yue-Qi Li, Yun-Qian Fang, Hong-Wen Zhang, Mei-Feng Wang, Li-Jun Xie, Juan Chen, Zhi-Cheng Yang, Ming-Liang Bian, Hao Li, Pei-Pei Zhang, Ji-Fu Wei, Ling Meng, Xue-Hui Zhang, Ping Zhao, Yong-Qing Wang
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Background: Not all patients with acid-related disorders receiving proton pump inhibitor (PP) treatment get adequate gastric pH control. The genetic variation of receptors, metabolic enzymes, and transporters are known to cause failures of therapies.
Externí odkaz:
https://doaj.org/article/8982e77b08fb442cab61ad012d66e36d
Autor:
Yu-Jiao Guo, Tian-Tian Du, Yan-Ling Yang, Yang Zhao, Xiang-Long Chen, Hong Ma, Lu-Ning Sun, Yong-Qing Wang
Publikováno v:
Therapeutic Drug Monitoring; Oct2024, Vol. 46 Issue 5, p634-641, 8p
Autor:
Shi-Yu Wen, Hong Ma, Xiang-Long Chen, Yang Zhao, Yan Liu, Yue Li, Chao Lu, Yong-Qing Wang, Lu-Ning Sun
Publikováno v:
Bioanalysis. 14:1497-1508
Aim: Caffeine is a central nervous system stimulant, used to treat apnea of prematurity. A hydrophilic interaction chromatography–tandem mass spectrometry (HILIC-MS/MS) approach was developed to detect caffeine, paraxanthine, theophylline and theob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e4d00cf9afa324c4c95c9748c121f9e
https://doi.org/10.4155/bio-2022-0131
https://doi.org/10.4155/bio-2022-0131
Autor:
Lu‐Ning Sun, Yang Zhao, Hua‐Ye Gao, Yan‐Ling Yang, Xu‐Ping Qian, Shi‐Yu Sun, Yu Wang, Li Ding, Yong‐Qing Wang
Publikováno v:
Journal of Separation Science. 45:2543-2554
Pivmecillinam, the ester of biologically active antibiotic mecillinam, is an effective oral preparation to treat urinary tract infections. To study pharmacokinetics in humans, LC-MS/MS methods were developed to quantify pivmecillinam and mecillinam i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba24a6817a9aed62239c296016efc5b1
https://doi.org/10.1002/jssc.202200070
https://doi.org/10.1002/jssc.202200070
Autor:
Lu-Ning Sun, Ye Zhang, Qiu-Chen Fang, Ye Shen, Xue Li, Chao Chen, Hong-Wen Zhang, Yong-Qing Wang
Publikováno v:
Bioanalysis. 14:307-316
Aim: HCP002, a phosphate-modified derivative of voriconazole, can improve solubility without using the nephrotoxic solubilizer, sulfobutylether-β-cyclodextrin. To study pharmacokinetics in humans, LC-MS/MS methods to quantify HCP002 in human plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f9f28ef608221a0549cb3c1ed3282c
https://doi.org/10.4155/bio-2021-0246
https://doi.org/10.4155/bio-2021-0246