Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lu-Lu Kong"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Once DNA breaks occur, poly(ADP-ribose) polymerase 1 (PARP1) ADP-ribosylates itself and other DNA repair factors to initiate the repair process. Here, the authors resolve the crystal structures of mouse and human HPF1, and human HPF1/PARP1 complex pr
Externí odkaz:
https://doaj.org/article/5521b4d0d2ee4c4d8454f7128bbf8047
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Upon binding to DNA breaks, poly(ADP-ribose) polymerase 1 (PARP1) ADP-ribosylates itself and other factors to initiate DNA repair. Serine is the major residue for ADP-ribosylation upon DNA damage, which strictly depends on HPF1. Here, we report the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62e69b10f1556266949c508b2bfe76c
https://doaj.org/article/5521b4d0d2ee4c4d8454f7128bbf8047
https://doaj.org/article/5521b4d0d2ee4c4d8454f7128bbf8047
Upon binding to DNA breaks, poly(ADP-ribose) polymerase 1 (PARP1) ADP-ribosylates itself and other factors to initiate DNA repair. Serine is the major residue for ADP-ribosylation upon DNA damage, which strictly depends on HPF1. Here we report the cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f70fe30fec1cd142310ad6429acad6a5
https://doi.org/10.21203/rs.3.rs-71025/v1
https://doi.org/10.21203/rs.3.rs-71025/v1
Publikováno v:
Fishshellfish immunology. 104
Tumor necrosis factor-α (TNF-α) is a pluripotent mediator of pro-inflammatory and antimicrobial defense mechanisms and a regulator of lymphoid organ development. Although two types of TNF-α have been identified in several teleost species, their fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe7c88425343fd6298a3fefc1702074
https://pubmed.ncbi.nlm.nih.gov/32585357
https://pubmed.ncbi.nlm.nih.gov/32585357
Publikováno v:
Fishshellfish immunology. 100
As a central pro-inflammatory cytokine, interleukin-1β (IL-1β) plays critical roles in the inflammatory response, pathogen infection, and immunological challenges in mammals. Although fish IL-1β has been confirmed to participate in inflammatory re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19b17d7f5643135e50511ddea820416
https://pubmed.ncbi.nlm.nih.gov/32173451
https://pubmed.ncbi.nlm.nih.gov/32173451
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 256:110643
Mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 3 (MEKK3) is a serine/threonine protein kinase that acts as a key regulator and is widely involved in various innate and acquired immune signaling pathways. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6dd908b8d87a26c154166a1e8129208
https://doi.org/10.1016/j.cbpb.2021.110643
https://doi.org/10.1016/j.cbpb.2021.110643
Autor:
Li Wang, Beilei Wang, Aoli Wang, Qiang Wang, Lu-Lu Kong, Fan Wu, Feiyang Liu, Xiaochuan Liu, Cheng Chen, Jing Liu, Yanjie Ruan, Wenchao Wang, Huiping Wang, Cai-Hong Yun, Ziping Qi, Wei Wang, Fengming Zou, Shanchun Zhang, Ji-Yun Chen, Zhenquan Hu, Chen Hu, Zhimin Zhai, Qi Shuang, Juan Liu, Qingsong Liu
Publikováno v:
Oncotarget
// Su Hang 1, 2 , Agnes F.Y. Tiwari 1 , Hextan Y.S. Ngan 3 , Yim-Ling Yip 4 , Annie L.M. Cheung 4 , Sai Wah Tsao 4 , Wen Deng 1 1 School of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China 2 College of Fore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89940ee2389662bcd4c755bd79a45d47
https://doi.org/10.18632/oncotarget.10037
https://doi.org/10.18632/oncotarget.10037
Autor:
Li-Yan Fan, Lu-Lu Kong
Publikováno v:
Chinese Chemical Letters. 27:827-831
A series of bioactive quinazolinones were effectively synthesized by the condensation of halide benzamide with amino acid using magnetically recyclable GO/Fe 3 O 4 –CuI as catalyst. Magnetic GO/Fe 3 O 4 –CuI was prepared via a simple chemical met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdba7888b8cf15ed38e1ff3bbedc6185
https://doi.org/10.1016/j.cclet.2016.01.055
https://doi.org/10.1016/j.cclet.2016.01.055
Publikováno v:
Biochemical and biophysical research communications. 488(2)
Drug-resistance is a major challenge in targeted therapy of EGFR mutated non-small cell lung cancers (NSCLCs). The third-generation irreversible inhibitors such as AZD9291, CO-1686 and WZ4002 can overcome EGFR T790M drug-resistance mutant through cov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e570f4f7cb7611884c0af8f037868fb
https://pubmed.ncbi.nlm.nih.gov/28456628
https://pubmed.ncbi.nlm.nih.gov/28456628
Publikováno v:
Journal of Intelligent Manufacturing. 26:1217-1232
With ever-increasing understanding of environmental and societal concerns, the focus of manufacturing industries, worldwide, is fast changing from mere profit-making to ensuring sustainability. The companies are striving hard to make their manufactur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec371d88e982bba9f17013bcfee1db1b
https://doi.org/10.1007/s10845-013-0851-x
https://doi.org/10.1007/s10845-013-0851-x