Zobrazeno 1 - 10 of 36 pro vyhledávání: '"Lu Jun Shen"'
2
Akademický článek
Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma
Autor: Ze-Xian Liu, Wei Xiao, Jing-Jing Zhao, Qiu-Zhong Pan, De-Sheng Weng, Yi Que, Xiao-Long Zhang, Xi-Zhi Wen, Bu-Shu Xu, Dong-Chun Hong, Tian-Hui Guo, Lu-Jun Shen, Wei-Jun Fan, Huo-Ying Chen, Hai-Rong Xu, Peng-Hui Zhou, Yi-Zhuo Zhang, Xiao-Hui Niu, Xing Zhang
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background The advent of immune checkpoint therapy has been a tremendous advance in cancer treatment. However, the responses are still insufficient in patients with soft tissue sarcoma (STS). We aimed to identify rational combinations to increase the
Externí odkaz: https://doaj.org/article/e988ecebac5347968984760e03511f4d
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3
Akademický článek
Investigating Mechanisms of Response or Resistance to Immune Checkpoint Inhibitors by Analyzing Cell-Cell Communications in Tumors Before and After Programmed Cell Death-1 (PD-1) Targeted Therapy: An Integrative Analysis Using Single-cell RNA and Bulk-RNA Sequencing Data
Autor: Yi-Quan Jiang, Zi-Xian Wang, Ming Zhong, Lu-Jun Shen, Xue Han, Xuxiazi Zou, Xin-Yi Liu, Yi-Nan Deng, Yang Yang, Gui-Hua Chen, Wuguo Deng, Jin-Hua Huang
Publikováno v: OncoImmunology, Vol 10, Iss 1 (2021)
Currently, a significant proportion of cancer patients do not benefit from programmed cell death-1 (PD-1)-targeted therapy. Overcoming drug resistance remains a challenge. In this study, single-cell RNA sequencing and bulk RNA sequencing data from sa
Externí odkaz: https://doaj.org/article/69931149762342a5b49c13e2823b4304
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4
Akademický článek
Safety and effectiveness of multi-antenna microwave ablation-oriented combined therapy for large hepatocellular carcinoma
Autor: Tian-qi Zhang, Zhi-mei Huang, Jing-xian Shen, Gui-qun Chen, Lu-jun Shen, Fei Ai, Yang-kui Gu, Wang Yao, Yan-yang Zhang, Rong-ping Guo, Min-shan Chen, Jin-hua Huang
Publikováno v: Therapeutic Advances in Gastroenterology, Vol 12 (2019)
Background: In patients with a large, unresectable hepatocellular carcinoma (HCC), the primary recommendation is for transarterial chemoembolization (TACE) but used alone TACE is not typically curative. Combinations of TACE followed in a delayed fash
Externí odkaz: https://doaj.org/article/2ec40633033e4fad953623c6f28dd950
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5
Genomic profiling of radiation-induced sarcomas reveals the immunological characteristics and its response to immune checkpoint blockade
Autor: Dong-Chun Hong, Jing Yang, Cong Sun, Yuan-Tao Liu, Lu-Jun Shen, Bu-Shu Xu, Yi Que, Xiaojun Xia, Xing Zhang
Publikováno v: Clinical Cancer Research.
Purpose: Radiation-induced sarcomas (RISs) have poor prognosis and lack effective treatments. Its genome and tumor microenvironment are not well characterized and need further exploration. Experimental Design: Here, we perform whole exome (WES) and m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c956efaa08a643951dadaeeeba02052
https://doi.org/10.1158/1078-0432.ccr-22-3567
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6
Akademický článek
Overweight/obese status associates with favorable outcome in patients with metastatic nasopharyngeal carcinoma: a 10-year retrospective study
Autor: Wang Li, Lu-Jun Shen, Tao Chen, Xu-Qi Sun, Ying Zhang, Ming Wu, Wan-Hong Shu, Chen Chen, Chang-Chuan Pan, Yun-Fei Xia, Pei-Hong Wu
Publikováno v: Chinese Journal of Cancer, Vol 35, Iss 1, Pp 1-9 (2016)
Abstract Background Although the prognostic impact of body mass index (BMI) in patients with non-metastatic nasopharyngeal carcinoma (NPC) had been extensively studied, its effect among metastatic NPC patients remains unknown. The purpose of this stu
Externí odkaz: https://doaj.org/article/135fb894e12a4ac991d01557397e1c0d
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7
Eight key long non-coding RNAs predict hepatitis virus positive hepatocellular carcinoma as prognostic targets
Autor: Zi Lin Huang, Pei Hong Wu, Wang Li, Qifeng Chen, Lu Jun Shen
Publikováno v: World Journal of Gastrointestinal Oncology
BACKGROUND Hepatitis B virus, together with hepatitis C virus, has been recognized as the leading causes of hepatocellular carcinoma (HCC). Long non-coding RNAs (lncRNAs) have been suggested in increasing studies to be the potential prognostic factor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557d52a34cf5dfb62f8897c9ddacd98f
https://doi.org/10.4251/wjgo.v11.i11.983
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8
TFAP4 Promotes Hepatocellular Carcinoma Invasion and Metastasis via Activating the PI3K/AKT Signaling Pathway
Autor: Pei Hong Wu, Wang Li, Lu Jun Shen, Bo Yang Chang, Weijun Fan, Qifeng Chen, Tao Huang
Publikováno v: Disease Markers, Vol 2019 (2019)
Disease Markers
Transcription factor activating enhancer binding protein 4 (TFAP4) is established as a regulator of human cancer genesis and progression. Overexpression of TFAP4 indicates poor prognosis in various malignancies. The current study was performed to qua
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84936e858bbfc02b47ab0b2c03f3c4b
https://doi.org/10.1155/2019/7129214
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10
Akademický článek
High weight loss during radiation treatment changes the prognosis in under-/normal weight nasopharyngeal carcinoma patients for the worse: a retrospective analysis of 2433 cases.
Autor: Lu-Jun Shen, Chen Chen, Bo-Fei Li, Jin Gao, Yun-Fei Xia
Publikováno v: PLoS ONE, Vol 8, Iss 7, p e68660 (2013)
BACKGROUND:Although weight loss is common in nasopharyngeal carcinoma (NPC) patients receiving radiotherapy, the prognostic influence of weight loss and its impact modified by body mass index (BMI) are still unclear. METHODS:2433 NPC patients receivi
Externí odkaz: https://doaj.org/article/a72383fcf6bf4845b8c4dd9ea16566b9
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