Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Luísa V. Lopes"'
Autor:
Ana Chegão, Mariana Guarda, Bruno M. Alexandre, Liana Shvachiy, Mariana Temido-Ferreira, Inês Marques-Morgado, Bárbara Fernandes Gomes, Rune Matthiesen, Luísa V. Lopes, Pedro R. Florindo, Ricardo A. Gomes, Patrícia Gomes-Alves, Joana E. Coelho, Tiago Fleming Outeiro, Hugo Vicente Miranda
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-22 (2022)
Abstract Alpha-synuclein (aSyn) is a central player in the pathogenesis of synucleinopathies due to its accumulation in typical protein aggregates in the brain. However, it is still unclear how it contributes to neurodegeneration. Type-2 diabetes mel
Externí odkaz:
https://doaj.org/article/505e44be1dd441bfb7ad630258f5cddb
Autor:
Catarina B. Ferreira, Mikael Marttinen, Joana E. Coelho, Kaisa M.A. Paldanius, Mari Takalo, Petra Mäkinen, Luukas Leppänen, Catarina Miranda-Lourenço, João Fonseca-Gomes, Sara R. Tanqueiro, Sandra H. Vaz, Rita F. Belo, Ana Maria Sebastião, Ville Leinonen, Hilkka Soininen, Ian Pike, Annakaisa Haapasalo, Luísa V. Lopes, Alexandre de Mendonça, Maria José Diógenes, Mikko Hiltunen
Publikováno v:
Neurobiology of Disease, Vol 163, Iss , Pp 105603- (2022)
Alzheimer's disease (AD) is the most common form of dementia, which is neuropathologically characterized by extracellular senile plaques containing amyloid-β and intracellular neurofibrillary tangles composed of hyperphosphorylated tau protein. Prev
Externí odkaz:
https://doaj.org/article/64ca49ebf34d4f8fba3b77430bcc78cd
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
IntroductionDifferences in the manner circadian clocks entrain to the 24-h day are expressions of different chronotypes that can range from extreme early to extreme late, from proverbial larks to owls. The Morningness Eveningness Questionnaire (MEQ)
Externí odkaz:
https://doaj.org/article/4ff15a93f187463ab8b68bed7543e372
Autor:
Aleix Martí Navia, Diego Dal Ben, Catia Lambertucci, Andrea Spinaci, Rosaria Volpini, Inês Marques-Morgado, Joana E. Coelho, Luísa V. Lopes, Gabriella Marucci, Michela Buccioni
Publikováno v:
Cells, Vol 9, Iss 7, p 1739 (2020)
The pathological condition of neuroinflammation is caused by the activation of the neuroimmune cells astrocytes and microglia. The autacoid adenosine seems to be an important neuromodulator in this condition. Its main receptors involved in the neuroi
Externí odkaz:
https://doaj.org/article/a24a4f37361f4bbc94dc26f2ec1fc4b4
Autor:
Sara R. Tanqueiro, Rita M. Ramalho, Tiago M. Rodrigues, Luísa V. Lopes, Ana M. Sebastião, Maria J. Diógenes
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Brain-derived neurotrophic factor (BDNF) plays important functions in cell survival and differentiation, neuronal outgrowth and plasticity. In Alzheimer’s disease (AD), BDNF signaling is known to be impaired, partially because amyloid β (Aβ) indu
Externí odkaz:
https://doaj.org/article/9825c12b389b45e5bdf16705ffc339de
© 2023 The Authors. Journal of Pineal Research published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e7abec86561710226114e3ae573f04
https://hdl.handle.net/10400.14/40740
https://hdl.handle.net/10400.14/40740
Autor:
Joana Rajão‐Saraiva, Jade Dunot, Aurore Ribera, Mariana Temido‐Ferreira, Joana E. Coelho, Svenja König, Sébastien Moreno, Francisco J. Enguita, Michael Willem, Stefan Kins, Hélène Marie, Luísa V. Lopes, Paula A. Pousinha
Publikováno v:
Aging Cell. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::166af80542ef186ea88b1497f4ce61b1
https://doi.org/10.1111/acel.13778
https://doi.org/10.1111/acel.13778
Autor:
Luísa V. Lopes
Publikováno v:
Journal of Caffeine and Adenosine Research. 11:69-74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c66cfc1c3ad528cffc0748067174194
https://doi.org/10.1089/caff.2021.29025.lvl
https://doi.org/10.1089/caff.2021.29025.lvl
Autor:
Kubra Gulmez Karaca, Benjamin Zeuch, Janina Kupke, Luísa V. Lopes, Ana M.M. Oliveira, Franziska Mudlaff, Rui Gomes, David V.C. Brito
Publikováno v:
Neurobiology of Aging. 94:281-286
Aging is associated with the progressive decay of cognitive function. Hippocampus-dependent processes, such as the formation of spatial memory, are particularly vulnerable to aging. Currently, the molecular mechanisms responsible for age-dependent co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1bf57905141c40f1c6b6f345c2eeb4a
https://doi.org/10.1016/j.neurobiolaging.2020.06.021
https://doi.org/10.1016/j.neurobiolaging.2020.06.021
Autor:
Luísa V. Lopes, Diana Chapela, Sara Sousa, Tiago F. Outeiro, Nuno Afonso, Joaquim J. Ferreira, Joana E. Coelho, Rita L. Vaz
Publikováno v:
Neuroscience. 424:58-71
The motor features in Parkinson's disease (PD) are associated with the degeneration of dopaminergic cells in the substantia nigra in the brain. Thus, the gold-standard in PD therapeutics still consists of dopamine replacement with levodopa. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93c2c351efd2e1c955497829378b42f
https://doi.org/10.1016/j.neuroscience.2019.08.046
https://doi.org/10.1016/j.neuroscience.2019.08.046