Výsledky vyhledávání - "Luís Madero"

Akademický článek

Nuclear factor-κ B inducing kinase is required for graft-versus-host disease

Autor: Carmen Sánchez-Valdepeñas, Lucía Casanova, Isabel Colmenero, Mar Arriero, África González, Nieves Lozano, Marta González-Vicent, Miguel A. Díaz, Luís Madero, Manuel Fresno, Manuel Ramírez

Publikováno v: Haematologica, Vol 95, Iss 12 (2010)

Background Donor T lymphocytes are directly responsible for graft-versus-host disease. Molecules important in T-cell function may, therefore, be appropriate targets for graft-versus-host disease therapy and/or prophylaxis. Here we analyzed whether nu

Externí odkaz: https://doaj.org/article/e2244563cc774ecb938de4fab2de5c43

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Akademický článek

Safety and outcome of children, adolescents and young adults participating in phase I/II clinical oncology trials: a 9-year center experience

Publikováno v: Frontiers in Pediatrics, Vol 12 (2024)

IntroductionEnrolling children with cancer in early phase trials is crucial to access innovative treatments, contributing to advancing pediatric oncology research and providing tailored therapeutic options. Our objective is to analyze the impact of t

Externí odkaz: https://doaj.org/article/350a5d42153f4c9d8da4b8712bc245e8

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Akademický článek

Role of the mesenchymal stromal cells in bone marrow failure of Fanconi Anemia patients

Autor: Josune Zubicaray, Maria Ivanova, June Iriondo, Jorge García Martínez, Rafael Muñoz-Viana, Lorea Abad, Lorena García-García, Jesús González de Pablo, Eva Gálvez, Elena Sebastián, Manuel Ramírez, Luis Madero, Miguel Ángel Díaz, África González-Murillo, Julián Sevilla

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

IntroductionFanconi anemia (FA) is an inherited disorder characterized by bone marrow failure, congenital malformations, and predisposition to malignancies. Alterations in hematopoietic stem cells (HSC) have been reported, but little is known regardi

Externí odkaz: https://doaj.org/article/a1912601287e4b89a684e68a105b628e

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Akademický článek

Use of glucarpidase (carboxypeptidase‐G2) in pediatric cancer patients: 11‐year experience of a tertiary center

Autor: Rocío Vila, Alba Rubio‐San‐Simón, Pablo Zubiaur, Marcos Navares‐Gómez, Patricia Gómez‐Hernández, Begoña Arce, Luis Madero

Publikováno v: eJHaem, Vol 4, Iss 4, Pp 1052-1058 (2023)

Abstract Methotrexate is an essential drug in the treatment of childhood cancer that is not exempt from toxicities. Glucarpidase is a drug used to reduce the toxic concentration of plasma methotrexate in patients with delayed elimination or at risk o

Externí odkaz: https://doaj.org/article/f6a87a0f10fe47de98de1f94c9a34490

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Akademický článek

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Akademický článek

Adverse events related to central venous catheters (CVC) and the influence of CVC characteristics on peripheral blood hematopoietic progenitor cell collection in children

Autor: Josune Zubicaray, Sofía Martin-Consuegra, Monserrat Nieto, Gustavo Albi, June Iriondo, Elena Sebastian, Eva Gálvez, Blanca Molina, Marta González-Vicent, Jesus Gonzalez de Pablo, Ana Castillo, Manuel Ramírez, Luis Madero, Miguel Angel Díaz, Julián Sevilla

Publikováno v: Frontiers in Pediatrics, Vol 11 (2023)

IntroductionThe use of peripheral blood progenitor cells (PBPCs) as a source for hematopoietic stem cell transplantation (HSCT) in pediatric healthy donors is still under debate. The risk of a central venous catheter (CVC) placement and catheter-rela

Externí odkaz: https://doaj.org/article/d50be8dcf4db4eaa802ca15d15d11cea

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