Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Luís Arnes"'
Autor:
Evangelina López de Maturana, Juan Antonio Rodríguez, Lola Alonso, Oscar Lao, Esther Molina-Montes, Isabel Adoración Martín-Antoniano, Paulina Gómez-Rubio, Rita Lawlor, Alfredo Carrato, Manuel Hidalgo, Mar Iglesias, Xavier Molero, Matthias Löhr, Christopher Michalski, José Perea, Michael O’Rorke, Victor Manuel Barberà, Adonina Tardón, Antoni Farré, Luís Muñoz-Bellvís, Tanja Crnogorac-Jurcevic, Enrique Domínguez-Muñoz, Thomas Gress, William Greenhalf, Linda Sharp, Luís Arnes, Lluís Cecchini, Joaquim Balsells, Eithne Costello, Lucas Ilzarbe, Jörg Kleeff, Bo Kong, Mirari Márquez, Josefina Mora, Damian O’Driscoll, Aldo Scarpa, Weimin Ye, Jingru Yu, PanGenEU Investigators, Montserrat García-Closas, Manolis Kogevinas, Nathaniel Rothman, Debra T Silverman, SBC/EPICURO Investigators, Demetrius Albanes, Alan A Arslan, Laura Beane-Freeman, Paige M Bracci, Paul Brennan, Bas Bueno-de-Mesquita, Julie Buring, Federico Canzian, Margaret Du, Steve Gallinger, J Michael Gaziano, Phyllis J Goodman, Marc Gunter, Loic LeMarchand, Donghui Li, Rachael E Neale, Ulrika Peters, Gloria M Petersen, Harvey A Risch, Maria José Sánchez, Xiao-Ou Shu, Mark D Thornquist, Kala Visvanathan, Wei Zheng, Stephen J Chanock, Douglas Easton, Brian M Wolpin, Rachael Z Stolzenberg-Solomon, Alison P Klein, Laufey T Amundadottir, Marc A Marti-Renom, Francisco X Real, Núria Malats
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Abstract Background Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% of the phenotypic var
Externí odkaz:
https://doaj.org/article/fd82873a71df49c79bdc3dadb14c043b
Autor:
Lewinska, Monika, Zhuravleva, Ekaterina, Satriano, Letizia, Martinez, Marta B., Bhatt, Deepak K., Oliveira, Douglas V.N.P., Antoku, Yasuko, Keggenhoff, Friederike L., Castven, Darko, Marquardt, Jens U., Matter, Matthias S., Erler, Janine T., Oliveira, Rui C., Aldana, Blanca I., Al-Abdulla, Ruba, Perugorria, Maria J., Calvisi, Diego F., Perez, Luis Arnes, Rodrigues, Pedro M., Labiano, Ibone, Banales, Jesus M., Andersen, Jesper B.
Publikováno v:
In Gastroenterology May 2024 166(5):886-901
Autor:
Kristina Høj, Jonathan Baldan, Philip Allan Seymour, Charlotte Vestrup Rift, Jane Preuss Hasselby, Albin Sandelin, Luis Arnes
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 7, Pp 973-985 (2024)
Background and Aims: The regenerative capacity of the pancreas diminishes with age. Understanding acinar cell responses to injury and the resolution of regenerative processes is crucial for tissue homeostasis. However, knowledge about the impact of a
Externí odkaz:
https://doaj.org/article/54576beb68bd4c64be54a302bcc3d6f7
Autor:
Maria Rafaeva, Adina R. D. Jensen, Edward R. Horton, Kamilla W. Zornhagen, Jan E. Strøbech, Lutz Fleischhauer, Alejandro E. Mayorca-Guiliani, Sebastian R. Nielsen, Dina S. Grønseth, Filip Kuś, Erwin M. Schoof, Luis Arnes, Manuel Koch, Hauke Clausen-Schaumann, Valerio Izzi, Raphael Reuten, Janine T. Erler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The desmoplastic reaction observed in many cancers is a hallmark of disease progression and prognosis, particularly in breast and pancreatic cancer. Stromal-derived extracellular matrix (ECM) is significantly altered in desmoplasia, and as such plays
Externí odkaz:
https://doaj.org/article/1b359b8013e44394a924f6031f8d7cb2
Autor:
Kazuya Tsujita, Reiko Satow, Shinobu Asada, Yoshikazu Nakamura, Luis Arnes, Keisuke Sako, Yasuyuki Fujita, Kiyoko Fukami, Toshiki Itoh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Changes in cell mechanics contribute to cancer cell dissemination. Here the authors show that high plasma membrane (PM) tension inhibits cancer dissemination by counteracting mechanosensitive BAR family protein assembly, while restoration of PM tensi
Externí odkaz:
https://doaj.org/article/cbe9da96697e4617972f9c2d3614eb29
Autor:
Sebastian R. Nielsen, Jan E. Strøbech, Edward R. Horton, Rene Jackstadt, Anu Laitala, Marina C. Bravo, Giorgia Maltese, Adina R. D. Jensen, Raphael Reuten, Maria Rafaeva, Saadia A. Karim, Chang-Il Hwang, Luis Arnes, David A. Tuveson, Owen J. Sansom, Jennifer P. Morton, Janine T. Erler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Tumor associated neutrophils have been correlated with poor prognosis in patients with pancreatic ductal adenocarcinoma (PDAC). Here the authors show that the tyrosine kinase inhibitor lorlatinib modulates neutrophil development and recruitment in th
Externí odkaz:
https://doaj.org/article/80c3347050694832b4503df3a10d5b8d
Autor:
Raúl Rabadán, Yamina Mohamedi, Udi Rubin, Tim Chu, Adam N. Alghalith, Oliver Elliott, Luis Arnés, Santiago Cal, Álvaro J. Obaya, Arnold J. Levine, Pablo G. Cámara
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Rare cancer mutations are often missed using recurrence-based statistical approaches, but are usually accompanied by changes in expression. Here the authors leverage this information to uncover several elusive candidate cancer-associated genes using
Externí odkaz:
https://doaj.org/article/704bc0872a5c4264834902454745c986
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
The transcriptional programs of differentiated cells are tightly regulated by interactions between cell type-specific transcription factors and cis-regulatory elements. Long non-coding RNAs (lncRNAs) have emerged as additional regulators of gene tran
Externí odkaz:
https://doaj.org/article/968038a22f9f439b81294cdabbc2f58a
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52026 (2012)
Pancreatic islet cells provide the major source of counteractive endocrine hormones required for maintaining glucose homeostasis; severe health problems result when these cell types are insufficiently active or reduced in number. Therefore, the proce
Externí odkaz:
https://doaj.org/article/e19ccee6be6c44609df375f6f6de82a7