Immune changes over time and survival in patients with cirrhosis treated with non-selective beta-blockers: A prospective longitudinal study.

Autor: Almenara S; CIBERehd, Health Institute Carlos III, Madrid, Spain; Clinical Pharmacology Unit. Alicante General University Hospital, Alicante, Spain; Institute of Research, Development, and Innovation in Healthcare Biotechnology of Elche (IDiBE), University Miguel Hernández de Elche, Spain; Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain., Lozano-Ruiz B; CIBERehd, Health Institute Carlos III, Madrid, Spain; Institute of Research, Development, and Innovation in Healthcare Biotechnology of Elche (IDiBE), University Miguel Hernández de Elche, Spain., Herrera I; Liver Unit. Alicante General University Hospital, Alicante, Spain., Gimenez P; CIBERehd, Health Institute Carlos III, Madrid, Spain., Miralles C; Liver Unit. Alicante General University Hospital, Alicante, Spain., Bellot P; Liver Unit. Alicante General University Hospital, Alicante, Spain., Rodriguez M; Liver Unit. Alicante General University Hospital, Alicante, Spain., Palazon JM; Liver Unit. Alicante General University Hospital, Alicante, Spain., Tarín F; Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain; Hematology Department. Alicante General University Hospital, Alicante, Spain., Sarmiento H; Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain; Hematology Department. Alicante General University Hospital, Alicante, Spain., Francés R; CIBERehd, Health Institute Carlos III, Madrid, Spain; Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain; Clinical Medicine Department, University Miguel Hernández de Elche, Alicante, Spain., Gonzalez-Navajas JM; CIBERehd, Health Institute Carlos III, Madrid, Spain; Institute of Research, Development, and Innovation in Healthcare Biotechnology of Elche (IDiBE), University Miguel Hernández de Elche, Spain; Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain., Pascual S; CIBERehd, Health Institute Carlos III, Madrid, Spain; Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain; Liver Unit. Alicante General University Hospital, Alicante, Spain., Zapater P; CIBERehd, Health Institute Carlos III, Madrid, Spain; Clinical Pharmacology Unit. Alicante General University Hospital, Alicante, Spain; Institute of Research, Development, and Innovation in Healthcare Biotechnology of Elche (IDiBE), University Miguel Hernández de Elche, Spain; Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain. Electronic address: pzapater@umh.es.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Jul; Vol. 163, pp. 114885. Date of Electronic Publication: 2023 May 16.

The Impact of Tregs on the Anticancer Immunity and the Efficacy of Immune Checkpoint Inhibitor Therapies

Autor: Gonzalez-Navajas J, Fan D, Yang S, Yang F, Lozano-Ruiz B, Shen L, Lee J

Publikováno v: Frontiers in Immunology
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname

Although cancers arise from genetic mutations enabling cells to proliferate uncontrollably, they cannot thrive without failure of the anticancer immunity due in a large part to the tumor environment's influence on effector and regulatory T cells. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::e8e30c17116b98c1914862e740e7e78f
https://fundanet.isabial.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7438

AIM2 deficiency reduces the development of hepatocellular carcinoma in mice

Autor: Martínez-Cardona C, Lozano-Ruiz B, Bachiller V, Peiró G, Algaba-Chueca F, Gómez-Hurtado I, Such J, Zapater P, Francés R, González-Navajas JM

Publikováno v: INTERNATIONAL JOURNAL OF CANCER
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante

Chronic liver inflammation is crucial in the pathogenesis of hepatocellular carcinoma (HCC). Activation of the inflammasome complex is a key inflammatory process that has been associated with different liver diseases, but its role in HCC development

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::071fdb6b0288dcde8ccb39d677bbe7da
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=2474

Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis.

Autor: Zhang, Yu¹ (AUTHOR), Wu, Rong¹ (AUTHOR), Zhan, Xi¹ (AUTHOR), Wang, Xuan-Yi² (AUTHOR), Xiang, Lin-Wei³ (AUTHOR), Duan, Ya-Qian¹ (AUTHOR), You, Yan² (AUTHOR), Zhang, Jian-Bo⁴ (AUTHOR), Wu, Rui⁵ (AUTHOR) wurui@cqmu.edu.cn, Zhang, Yun-Yuan⁶ (AUTHOR) hellozyycool@qdu.edu.cn, Duan, Liang¹ (AUTHOR) duanliang@cqmu.edu.cn

Publikováno v: Cell Communication & Signaling. 11/20/2024, Vol. 22 Issue 1, p1-17. 17p.

Eosinophil–Basophil/Lymphocyte (EB/LR) and Eosinophil–Basophil–Platelet/Lymphocyte (EBP/LR) Ratios Could Serve as Useful Additional Markers for Assessing the Severity of Wasp Allergic Reactions.

Autor: Urbańska, Weronika¹ (AUTHOR), Szymański, Łukasz² (AUTHOR) l.szymanski@igbzpan.pl, Lewicka, Aneta³ (AUTHOR), Ciepielak, Martyna⁴ (AUTHOR), Kostrzeńska-Sęk, Karolina⁵ (AUTHOR), Chciałowski, Andrzej¹ (AUTHOR), Lewicki, Sławomir⁵ (AUTHOR) l.szymanski@igbzpan.pl

Publikováno v: Cells (2073-4409). Nov2024, Vol. 13 Issue 21, p1786. 14p.