Targeting heterogeneous tumor microenvironments in pancreatic cancer mouse models of metastasis by TGF-β depletion.

Autor: Chen SY; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and.; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Kung HC; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and., Espinoza B; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and., Washington I; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and., Chen K; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and., Wang J; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and., Zlomke H; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and., Loycano M; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and., Wang R; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center., Pickup M; Bristol Myers Squibb, Princeton, New Jersey, USA., Burns WR 3rd; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and.; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Fu J; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and., Hwang WL; Center for Systems Biology, Department of Radiation Oncology, Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Zheng L; Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center.; Pancreatic Cancer Precision Medicine Center of Excellence Program, and.; Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Publikováno v: JCI insight [JCI Insight] 2024 Nov 08; Vol. 9 (21). Date of Electronic Publication: 2024 Nov 08.