Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lowri M. Davies"'
Publikováno v:
The Journal of Physiology. 588:3255-3266
ATP-sensitive potassium channels (KATP channels) of arterial smooth muscle are important regulators of arterial tone, and hence blood flow, in response to vasoactive transmitters. Recent biochemical and electron microscopic evidence suggests that the
Publikováno v:
The Journal of Physiology. 587:3639-3650
Exchange proteins directly activated by cyclic AMP (Epacs or cAMP-GEF) represent a family of novel cAMP-binding effector proteins. The identification of Epacs and the recent development of pharmacological tools that discriminate between cAMP-mediated
Publikováno v:
Cardiovascular Research. 76:61-70
The vasoconstrictor angiotensin II (Ang II) acts at G(q/11)-coupled receptors to suppress ATP-sensitive potassium (K(ATP)) channel activity via activation of protein kinase C (PKC). The aim of this study was to determine the PKC isoforms involved in
Publikováno v:
Biophysical Journal. 98(3)
Caveolae are small vesicular invaginations of the plasma membrane enriched in cholesterol, sphingolipids and the cholesterol-binding protein, caveolin [1]. Aside from roles in caveolae formation and stability, caveolins interact with many caveolae-lo
Publikováno v:
Biophysical Journal. (3):138a
Exchange proteins directly activated by cyclic AMP (Epac or cAMP-GEFs) are a family of novel cAMP-binding effector proteins [1]. Using the Epac-specific cAMP analogue 8-pCPT-2¯-O-Me-cAMP we show cAMP-mediated but PKA-independent mobilization of Ca2+