Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Lown, Kenneth S."'
Autor:
Hollenberg, Paul F., Edwards, David J., He, Kan, Fitzsimmons, Michael E., Fisher, Jeannine M., Rahman, Atiqur, Thummel, Kenneth E., Lown, Kenneth S., Woster, Patrick M., Schmiedlin-Ren, Phyllissa, Watkins, Paul B.
Grapefruit juice increases the oral availability of a variety of CYP3A4 substrates. It has been shown that recurrent grapefruit juice ingestion results in a loss of CYP3A4 from the small bowel epithelium. We now show that the reduction in intestinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66a142be1b7e9a07fc41ee694cde7025
Autor:
Hsiao, Hsiu-ling, Benet, Leslie Z., Schmiedlin-Ren, Phyllissa, Brown, Morton B., Turgeon, D. Kim, Mayo, Robert R., Lown, Kenneth S., Watkins, Paul B., Guo, Wensheng, Rossi, Stephen J., Leichtman, Alan B.
Interpatient differences in the oral clearance of cyclosporine (INN, ciclosporin) have been partially attributed to variation in the activity of a single liver enzyme termed CYP3A4. Recently it has been shown that small bowel also contains CYP3A4, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a679f1e01586302b2c73fe73757276c7
Autor:
Watkins, Paul B., Wrighton, Steven A., Barnett, Jeffrey L., Lown, Kenneth S., Kunze, Kent L., Thummel, Kenneth E., Kolars, Joseph C.
The CYP3A subfamily of cytochromes P450 metabolize many medications and environmental contaminants. CYP3A4 and, in 25% of patients, CYP3A5 seem to be the major CYP3A genes expressed in adult liver. Hepatic levels of CYP3A4 can be estimated by the ery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cb639a083fb3fb361635dbf9fb7ff44
Autor:
Mouly, Stéphane, Lown, Kenneth S., Kornhauser, David, Joseph, Jeffrey L., Fiske, William D., Benedek, Irma H., Watkins, Paul B.
Publikováno v:
Clinical Pharmacology & Therapeutics; Jul2002, Vol. 72 Issue 1, p1-9, 9p
Autor:
Janardan, Srinivas K., Lown, Kenneth S., Schmiedlin-Ren, Phyllissa, Thummel, Kenneth E., Watkins, Paul B.
Publikováno v:
Pharmacogenetics; Oct1996, Vol. 6 Issue 5, p379-385, 7p
Autor:
Kolars, Joseph C., Lown, Kenneth S., Schmiedlin-Ren, Phyllissa, Ghosh, Mita, Fang, Che, Wrighton, Steven A., Merion, Robert M., Watkins, Paul B.
Publikováno v:
Pharmacogenetics; Oct1994, Vol. 4 Issue 5, p247-259, 13p
Autor:
Lown, Kenneth S., Mayo, Robert R., Leichtman, Alan B., Hsiao, Hsiu-ling, Turgeon, D. Kim, Schmiedlin-Ren, Phyllissa, Brown, Morton B., Guo, Wensheng, Rossi, Stephen J., Benet, Leslie Z., Watkins, Paul B.
Publikováno v:
Clinical Pharmacology & Therapeutics; Sep1997, Vol. 62 Issue 3, p248-260, 13p
Autor:
Lown, Kenneth S., Thummel, Kenneth E., Benedict, Patrick E., Shen, Danny D., Turgeon, Danielle K., Berent, Stanley, Watkins, Paul B.
Publikováno v:
Clinical Pharmacology & Therapeutics; Jan1995, Vol. 57 Issue 1, p16-24, 9p
Autor:
Turgeon, D Kim, Leichtman, Alan B, Lown, Kenneth S, Normolle, Daniel P, Deeb, G Michael, Merion, Robert M, Watkins, Paul B
Publikováno v:
Clinical Pharmacology & Therapeutics; Sep1994, Vol. 56 Issue 3, p253-260, 8p
Autor:
Watkins, Paul B, Turgeon, D Kim, Saenger, Paul, Lown, Kenneth S, Kolars, Joseph C, Hamilton, Ted, Fishman, Kenneth, Guzelian, Philip S, Voorhees, John J
Publikováno v:
Clinical Pharmacology & Therapeutics; Sep1992, Vol. 52 Issue 3, p265-273, 9p